Treatment of implant-associated infections with moxifloxacin: an animal study

International Journal of Antimicrobial Agents

Volumn 27, Issue 5, 2006, Pages 444-448

  Kalteis, Thomas ^a   Beckmann, Johannes ^a   Schröder, Hans Jürgen ^a   Schaumburger, Jens ^a   Linde, Hans Jörg ^a   Lerch, Klaus ^a   Lehn, Norbert ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Implant associated infection; Moxifloxacin; Prosthetic infection; Staphylococcus aureus

Indexed keywords

MOXIFLOXACIN; VANCOMYCIN; ANTIINFECTIVE AGENT; HETEROCYCLIC COMPOUND; QUINOLINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL COUNT; BACTERIUM CONTAMINATION; BIOFILM; BONE; BONE PROSTHESIS; COLONY FORMING UNIT; CONTROLLED STUDY; DEVICE INFECTION; DISEASE ASSOCIATION; DRUG EFFICACY; FEMUR; IMPLANTATION; MALE; NONHUMAN; OSTEOMYELITIS; PRIORITY JOURNAL; PROSTHESIS INFECTION; RAT; SOFT TISSUE; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; ANIMAL; DRUG EFFECT; IMPLANT; WISTAR RAT;

ANIMALS; ANTI-BACTERIAL AGENTS; AZA COMPOUNDS; BIOFILMS; IMPLANTS, EXPERIMENTAL; MALE; OSTEOMYELITIS; QUINOLINES; RATS; RATS, WISTAR; STAPHYLOCOCCAL INFECTIONS; VANCOMYCIN;

EID: 33646162894     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2005.12.003     Document Type: Article

References (35)

1. Dalhoff A. Pharmacodynamics of fluoroquinolones. J Antimicrob Chemother 43 Suppl. B (1999) 51-59
2. Jones M.E., Visser M.R., Klootwijk M., Heisig P., Verhoef J., and Schmitz F.J. Comparative activities of clinafloxacin, grepafloxacin, levofloxacin, moxifloxacin, ofloxacin, sparfloxacin, and trovafloxacin and nonquinolones linozelid, quinupristin-dalfopristin, gentamicin, and vancomycin against clinical isolates of ciprofloxacin-resistant and -susceptible Staphylococcus aureus strains. Antimicrob Agents Chemother 43 (1999) 421-423
3. Hoogkamp-Korstanje J.A., and Roelofs-Willemse J. Comparative in vitro activity of moxifloxacin against Gram-positive clinical isolates. J Antimicrob Chemother 45 (2000) 31-39
4. Kaatz G.W., Moudgal V.V., and Seo S.M. Identification and characterization of a novel efflux-related multidrug resistance phenotype in Staphylococcus aureus. J Antimicrob Chemother 50 (2002) 833-838
5. Ince D., Zhang X., and Hooper D.C. Activity of and resistance to moxifloxacin in Staphylococcus aureus. Antimicrob Agents Chemother 47 (2003) 1410-1415
6. Pong A., Thomson K.S., Moland E.S., Chartrand S.A., and Sanders C.C. Activity of moxifloxacin against pathogens with decreased susceptibility to ciprofloxacin. J Antimicrob Chemother 44 (1999) 621-627
7. Lister P.D. Pharmacodynamics of moxifloxacin and levofloxacin against Staphylococcus aureus and Staphylococcus epidermidis in an in vitro pharmacodynamic model. Clin Infect Dis 32 Suppl. 1 (2001) S33-S38
8. Firsov A.A., Vostrov S.N., Lubenko I.Y., Drlica K., Portnoy Y.A., and Zinner S.H. In vitro pharmacodynamic evaluation of the mutant selection window hypothesis using four fluoroquinolones against Staphylococcus aureus. Antimicrob Agents Chemother 47 (2003) 1604-1613
9. Muller M., Stass H., Brunner M., Moller J.G., Lackner E., and Eichler H.G. Penetration of moxifloxacin into peripheral compartments in humans. Antimicrob Agents Chemother 43 (1999) 2345-2349
10. Joukhadar C., Stass H., Muller-Zellenberg U., et al. Penetration of moxifloxacin into healthy and inflamed subcutaneous adipose tissues in humans. Antimicrob Agents Chemother 47 (2003) 3099-3103
11. Sharkey P.F., Hozack W.J., Rothman R.H., Shastri S., and Jacoby S.M. Insall Award paper. Why are total knee arthroplasties failing today?. Clin Orthop 404 (2002) 7-13
12. Aglietti P., and Baldini A. Risk factors and prevention of infections of hip and knee prostheses. J Chemother 12 Suppl. 2 (2000) 15-22 [in Italian]
13. Eveillard M., Mertl P., Canarelli B., et al. Risk of deep infection in first-intention total hip replacement. Evaluation concerning a continuous series of 790 cases. Presse Med 30 (2001) 1868-1875 [in French]
14. Peersman G., Laskin R., Davis J., and Peterson M. Infection in total knee replacement: a retrospective review of 6489 total knee replacements. Clin Orthop 392 (2001) 15-23
15. Nguyen L.L., Nelson C.L., Saccente M., Smeltzer M.S., Wassell D.L., and McLaren S.G. Detecting bacterial colonization of implanted orthopaedic devices by ultrasonication. Clin Orthop 403 (2002) 29-37
16. Garcia F., Lacleriga A., Monzon M., Leiva J., Oteiza C., and Amorena B. Application of a rat osteomyelitis model to compare in vivo and in vitro antibiotic efficacy against bacteria with high capacity to form biofilms. J Surg Res 79 (1998) 146-153
17. Monzon M., Garcia-Alvarez F., Lacleriga A., and Amorena B. Evaluation of four experimental osteomyelitis infection models by using precolonized implants and bacterial suspensions. Acta Orthop Scand 73 (2002) 11-19
18. Mayberry-Carson K.J., Tober-Meyer B., Smith J.K., Lambe D.W., and Costerton J.W. Bacterial adherence and glycocalyx formation in osteomyelitis experimentally induced with Staphylococcus aureus. Infect Immun 43 (1984) 825-833
19. Kaarsemaker S., Walenkamp G., and Vanderbogaard A.E.J. New model for chronic osteomyelitis with Staphylococcus aureus in sheep. Clin Orthop Relat Res 339 (1997) 246-252
20. Melcher G.A., Claudi B., Schlegel U., Perren S.M., Printzen G., and Munzinger J. Influence of type of medullary nail on the development of local infection. J Bone Joint Surg Br 76 (1994) 955-959
21. Blaser J., Vergères P., Widmer A.F., and Zimmerli W. In vivo verification of in vitro model of antibiotic treatment of device-related infection. Antimicrob Agents Chemother 39 (1995) 1134-1139
22. Arens S., Schlegel U., Printzen G., Ziegler W.J., Perren S.M., and Hansis M. Influence of materials for fixation implants on local infection. J Bone Joint Surg Br 78 (1996) 647-651
23. Chohofi M., Langlais F., Fourastier J., Minet J., Thomazeau H., and Cormier M. Pharmacokinetics, uses, and limitations of vancomycin-loaded bone cement. Int Orthop 22 (1998) 171-177
24. Saleh-Mghir A., Ameur N., Muller-Serieys C., et al. Combination of quinupristin-dalfopristin (Synercid) and rifampin is highly synergistic in experimental Staphylococcus aureus joint prosthesis infection. Antimicrob Agents Chemother 46 (2002) 1122-1124
25. Zimmerli W., Widmer A.F., Blatter M., Frei R., and Ochsner P.E. Role of rifampin for treatment of orthopaedic implant-related Staphylococcus aureus: a randomized controlled trial. JAMA 279 (1998) 1537-1541
26. Bourgoin A., Leone M., and Martin C. Role of glycopeptides in the treatment of septic complications after cardiac surgery. J Chemother 13 (2001) 112-118
27. Siaperas P., Pefanis A., Iliopoulos D., et al. Evidence of less severe aortic valve destruction after treatment of experimental staphylococcal endocarditis with vancomycin and dexamethasone. Antimicrob Agents Chemother 45 (2001) 3531-3537
28. Stevens D.L., Herr D., Lampiris H., Hunt J.L., Batts D.H., and Hafkin B. Linezolid versus vancomycin for the treatment of methicillin-resistant Staphylococcus aureus infections. Clin Infect Dis 34 (2002) 1481-1490
29. Shorr A.F., Kunkel M.J., and Kollef M. Linezolid versus vancomycin for Staphylococcus aureus bacteraemia: pooled analysis of randomized studies. J Antimicrob Chemother 56 (2005) 923-929
30. Al-Tawfiq J.A., and Aldaabil R.A. Community-acquired MRSA bacteremic necrotizing pneumonia in a patient with scrotal ulceration. J Infect 51 (2005) 241-243
31. Tice A.D., Hoaglund P.A., and Shoultz D.A. Outcomes of osteomyelitis among patients treated with outpatient parenteral antimicrobial therapy. Am J Med 114 (2003) 723-728
32. Rodvold K.A., and Neuhauser M. Pharmacokinetics and pharmacodynamics of fluoroquinolones. Pharmacotherapy 21 (2001) 233S-252S
33. Stass H., Kubitza D., and Schuhly U. Pharmacokinetics, safety and tolerability of moxifloxacin, a novel 8-methoxyfluoroquinolone, after repeated oral administration. Clin Pharmacokinet 40 Suppl. 1 (2001) 1-9
34. Cunha B.A. Intravenous to oral antibiotic switch therapy. Drugs Today (Barc) 37 (2001) 311-319
35. Giulieri S.G., Graber P., Ochsner P.E., and Zimmerli W. Management of infection associated with total hip arthroplasty according to a treatment algorithm. Infection 32 (2004) 222-228