The use of darbepoetin in infants with chronic renal impairment

Pediatric Nephrology

Volumn 21, Issue 5, 2006, Pages 694-697

  Durkan, Anne M ^a   Keating, Laura E ^a   Vigneux, Annette ^a   Geary, Denis F ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Anaemia; Darbepoetin; Dosing; Erythropoietin; Infant; Kidney failure

Indexed keywords

CREATININE; FERRITIN; FOLIC ACID; HEMOGLOBIN; IRON; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; TRANSFERRIN; VITAMIN;

ANEMIA; ARTICLE; BODY WEIGHT; CHRONIC KIDNEY DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG DOSE REDUCTION; DRUG DOSE REGIMEN; FOLLOW UP; HEMODIALYSIS; HUMAN; INFANT; INJECTION SITE INFLAMMATION; INJECTION SITE PAIN; IRON THERAPY; PRESCRIPTION; PRIORITY JOURNAL; SURGICAL TECHNIQUE; TREATMENT OUTCOME;

ANEMIA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; ERYTHROPOIETIN; FEMALE; FERRITINS; HEMATINICS; HEMOGLOBINS; HUMANS; INFANT; IRON; MALE; RENAL INSUFFICIENCY, CHRONIC; RETROSPECTIVE STUDIES; TRANSFERRIN; TREATMENT OUTCOME;

EID: 33646161234     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-006-0067-9     Document Type: Article

References (17)

1. Egrie JC, Dwyer E, Lykos M, Hitz A, Browne JK (1997) Novel erythropoiesis stimulating protein (NESP) has a longer half-life and greater in vivo biological activity than recombinant human erythropoietin (rHuEPO) (abstract). Blood 90:56
2. MacDougall IC, Gray SJ, Elston O, Breen C, Jenkins B, Browne J, Egrie J (1999) Pharmacokinetics of novel erythropoiesis stimulating protein compared with epoetin alfa in dialysis patients. J Am Soc Nephrol 10:2392-2395
3. Lerner G, Kale AS, Warady BA, Jabs S, Bunchman TE, Heatherington A, Olsen K, Messer-Mann L, Maroni BJ (2002) Pharmacokinetics of darbepoetin alfa in pediatric patients with chronic kidney disease. Pediatr Nephrol 17:933-937
4. Geary DF, Keating LE, Vigneux A, Stephens D, Hebert D, Harvey EA (2005) Darbepoetin alfa (Aranesp) in children with chronic renal failure. Kidney Int 68:1759-1765
5. De Palo T, Giordano M, Palumbo F, Bellantuono R, Messina G, Colella V, Caringella AD (2004) Clinical experience with darbepoetin alfa (NESP) in children undergoing hemodialysis. Pediatr Nephrol 19:337-340
6. Renal Association (2002) Treatment of adults and children with renal failure: Standards and audit measures, 3rd edn. Royal College of Physicians of London and the Renal Association, London
7. National Kidney Foundation (2001) K/DOQI clinical practice guidelines for anemia of chronic kidney disease: Update 2000. Am J Kidney Dis 37 [Supp 1]:S182-S238
8. Schroder C, The European Pediatric Peritoneal Dialysis Working Group (2003) The management of anemia in pediatric peritoneal dialysis patients. Pediatr Nephrol 18:805-809
9. Locatelli F, Olivares J, Walker R, Wilkie M, Jenkins B, Dewey C, Gray SJ (2001) Novel erythropoiesis stimulating protein for treatment of anemia in chronic renal insufficiency. Kidney Int 60:741-747
10. Scigalla P (1991) Effect of recombinant human erythropoietin treatment on renal anemia and body growth of children with end-stage renal disease. Contrib Nephrol 88:201-211
11. Bargman JM, Jones JE, Petro JM (1992) The pharmacokinetics of intraperitoneal erythropoietin administered undiluted or diluted in dialysate. Perit Dial Int 12:369-372
12. Emond A, Hawkins N, Pennock C, Golding G (1996) Haemoglobin and ferritin concentrations in infants at 8 months of age. Arch Dis Child 74:36-39
13. Jadoul M, Vanrenterghem Y, Foret M, Walker R, Gray SJ (2004) Darbepoetin alfa administered once monthly maintains haemoglobin levels in stable dialysis patients. Nephrol Dial Transplant 19:898-903
14. Brandt JR, Avner ED, Hickman RO, Watkins SL (1999) Safety and efficacy of erythropoietin in children with chronic renal failure. Pediatr Nephrol 13:143-147
15. Brem AS, Lambert C, Hill C, Kitsen J, Shemin DG (2000) Outcome data on pediatric dialysis patients from the End-stage Renal Disease Clinical Indicators Project. Am J Kidney Dis 36(2):310-317
16. Coyne D, Ling BN, Toto R, McDermott-Vitak AD, Trotman ML, Jackson L (2000) Novel erythropoiesis stimulating protein (NESP) corrects anemia in dialysis patients when administered at reduced dose frequency compared with recombinant-human erythropoietin (r-HuEPO) (abstract). J Am Soc Nephrol 11:3029A
17. Joy MS (2002) Darbepoetin alfa: A novel erythropoiesis-stimulating protein. Ann Pharmacother 36:1183-1192