Excitatory amino acid receptors in the periaqueductal gray mediate the cardiovascular response evoked by activation of dorsomedial hypothalamic neurons

Neuroscience

Volumn 139, Issue 3, 2006, Pages 1129-1139

  da Silva Jr , L G ^a   Menezes, R C A ^a   Villela, D C ^a   Fontes, M A P ^a  

^a ICB   (Brazil)

Author keywords

cardiovascular system; dorsomedial hypothalamus; excitatory amino acid; periaqueductal gray; stress

Indexed keywords

AMINO ACID RECEPTOR BLOCKING AGENT; BICUCULLINE METHIODIDE; DIZOCILPINE; EXCITATORY AMINO ACID RECEPTOR; KYNURENIC ACID; N METHYL DEXTRO ASPARTIC ACID;

ANIMAL EXPERIMENT; ARTICLE; CARDIOVASCULAR RESPONSE; CELL ACTIVATION; CONTROLLED STUDY; DRUG EFFECT; HEART RATE; LOCOMOTION; MALE; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRESSOR RESPONSE; PRIORITY JOURNAL; RAT; SYNAPTIC TRANSMISSION; TACHYCARDIA; THALAMUS DORSOMEDIAL NUCLEUS;

ANIMALS; BICUCULLINE; BLOOD PRESSURE; CARDIOVASCULAR SYSTEM; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID ANTAGONISTS; HYPOTHALAMUS; INJECTIONS, INTRAVENTRICULAR; MALE; MICROINJECTIONS; MOTOR ACTIVITY; NEURAL PATHWAYS; NEURONS; PERIAQUEDUCTAL GRAY; RATS; RATS, WISTAR; RECEPTORS, GLUTAMATE; TACHYCARDIA;

EID: 33646160608     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2005.12.041     Document Type: Article

References (32)

1. Albin R.L., Makowiec R.L., Hollingsworth Z., Dure L.S., Penney J.B., and Young A.B. Excitatory amino acid binding sites in the periaqueductal gray of the rat. Neurosci Lett 118 (1990) 112-115
2. Bailey T.W., and DiMicco J.A. Chemical stimulation of the dorsomedial hypothalamus elevates plasma ACTH in conscious rats. Am J Physiol Regul Integr Comp Physiol 280 (2001) R8-R15
3. Bandler R., Keay K., Floyd N., and Price J. Central circuits mediating patterned autonomic activity during passive vs. active emotional coping. Brain Res Bull 53 1 (2000) 95-104
4. Bandler R., and Shipley M.T. Columnar organization in the midbrain periaqueductal gray. modules for emotional expression?. Trends Neurosci 17 9 (1994) 379-389
5. Beart P.M., Summers R.J., Stephenson J.A., Cook C.J., and Christie M.J. Excitatory amino acid projections to the periaqueductal gray in the rat. a retrograde transport study utilizing D[3H]aspartate and [3H]GABA. Neuroscience 34 (1990) 163-176
6. Brown D.A., Higgins A.J., March S., and Smart T.G. Actions of GABA on mammalian neurones, axons and nerve terminals. In: DeFeudis F.V., and Mandel P. (Eds). Amino acid neurotransmitters (1981), Raven, New York 321-326
7. Cao W.H., Fan W., and Morrison S.F. Medullary pathways mediating specific sympathetic responses to activation of dorsomedial hypothalamus. Neuroscience 126 (2004) 229-240
8. Carrive P., Bandler R., and Dampney R.A.L. Somatic and autonomic integration in the midbrain of the unanesthetized decerebrate cat. a distinctive pattern evoked by excitation of neurons in the subtentorial portion of the midbrain periaqueductal gray. Brain Res 483 (1989) 251-258
9. Carrive P. The periaqueductal gray and defensive behavior. functional representation and neuronal organization. Behav Brain Res 58 (1993) 27-47
10. da Silva L.G., de Menezes R.C.A., Santos R.A.S., Campagnole-Santos M.J., and Fontes M.A.P. Role of periaqueductal gray on the cardiovascular response evoked by disinhibition of the dorsomedial hypothalamus. Brain Res 984 (2003) 206-214
11. Dampney R.A.L., Coleman M.J., Fontes M.A.P., Hirooka Y., Horiuchi J., Li Y.-W., Polson J.W., Potts P.D., and Tagawa T. Central mechanisms underlying short and long-term regulation of the cardiovascular system. Clin Exp Pharmacol Physiol 29 (2002) 261-268
12. De Novellis V., Stotz Potter E.H., Morin S.M., Rossi F., and DiMicco J.A. Hypothalamic sites mediating cardiovascular effects of microinjected bicuculline and EAAs in rats. Am J Physiol Regul Integr Comp Physiol 269 (1995) R131-R140
13. Depaulis A., Bandler R., and Vergnes M. Characterization of pretentorial periaqueductal gray matter neurons mediating intraspecific defensive behaviors in the rat by microinjections of kainic acid. Brain Res 486 (1989) 121-132
14. Depaulis A., Keay K.A., and Bandler R. Quiescence and hyporeactivity evoked by activation of cell bodies in the ventrolateral midbrain periaqueductal gray of the rat. Exp Brain Res 99 (1994) 75-83
15. DiMicco J.A., Samuels B.C., Zaretskaia M.V., and Zaretsky D.V. The dorsomedial hypothalamus and the response to stress. Part renaissance, part revolution. Pharmacol Biochem Behav 71 (2002) 469-480
16. Fontes M.A.P., Tagawa T., Polson J.W., Cavanagh S.J., and Dampney R.A.L. Descending pathways mediating cardiovascular response from dorsomedial hypothalamic nucleus. Am J Physiol Heart Circ Physiol 280 (2001) H2891-H2901
17. Horiuchi J., McAllen R.M., Allen A.M., Killinger S., Fontes M.A.P., and Dampney R.A.L. Descending vasomotor pathways from the dorsomedial hypothalamic nucleus; role of medullary raphe and RVLM. Am J Physiol Regul Integr Comp Physiol 287 (2004) R824-R832
18. Li J., and Mitchell J.H. Glutamate release in midbrain periaqueductal gray by activation of skeletal muscle receptors and arterial baroreceptors. Am J Physiol Heart Circ Physiol 285 (2003) H137-H144
19. Lu C.L., Shaikh M.B., and Siegel A. Role of NMDA receptors in hypothalamic facilitation of feline defensive rage elicited from the midbrain periaqueductal gray. Brain Res 581 (1992) 123-132
20. Paxinos G., and Watson C. The rat brain in stereotaxic coordinates. 2nd ed. (1986), Academic Press, New York
21. Samuels B.C., Zaretsky D.V., and DiMicco J.A. Dorsomedial hypothalamic sites where disinhibition evokes tachycardia correlate with location of raphe-projecting neurons. Am J Physiol Regul Integr Comp Physiol 287 (2004) R472-R478
22. Samuels B.C., Zaretsky D.V., and DiMicco J.A. Tachycardia evoked by disinhibition of the dorsomedial hypothalamus in rats is mediated through medullary raphe. J Physiol 538 (2002) 941-946
23. Shekhar A., and DiMicco J.A. Defense reaction elicited by injection of GABA antagonists and synthesis inhibitors into the posterior hypothalamus in rats. Neuropharmacology 26 (1987) 407-417
24. Shekhar A., Keim S.R., Simon J.R., and McBride W.J. Dorsomedial hypothalamic GABA dysfunction produces physiological arousal following sodium lactate infusions. Pharmacol Biochem Behav 55 2 (1996) 249-256
25. Soltis R.P., and DiMicco J.A. Hypothalamic excitatory amino acid receptors mediate stress-induced tachycardia in rats. Am J Physiol Regul Integr Comp Physiol 262 (1992) R689-R697
26. Stotz-Potter E.H., Morin S.M., and DiMicco J.A. Effect of microinjection of muscimol into dorsomedial or paraventricular hypothalamic nucleus on stress-induced neuroendocrine and cardiovascular changes in rats. Brain Res 742 (1996) 219-224
27. Stotz-Potter E.H., Willis L.R., and DiMicco J.A. Muscimol acts in dorsomedial and not paraventricular hypothalamic nucleus to suppress cardiovascular effects of stress. J Neurosci 16 (1996) 1173-1179
28. Ter Horst G.J., and Luiten P.G.M. The projections of the dorsomedial hypothalamic nucleus in the rat. Brain Res Bull 16 (1986) 231-248
29. Thompson R.H., Canteras N.S., and Swanson L.W. Organization of projections from the dorsomedial nucleus of the hypothalamus. a PHA-L study in the rat. J Comp Neurol 376 (1996) 143-173
30. Tölle T.R., Berthele A., Zieglgansberger W., Seeburg P.H., and Wisden W. The differential expression of 16 NMDA and non-NMDA receptor subunits in the rat spinal cord and in periaqueductal gray. J Neurosci 13 12 (1993) 5009-5028
31. Wiklund L., Behzadi G., Kalen P., Headley P.M., Nicopoulos L.S., Parsons C.G., and West D.C. Autoradiographic and electrophysiological evidence for excitatory amino acid transmission in the periaqueductal gray projection to nucleus raphe magnus in the rat. Neurosci Lett 93 (1988) 158-163
32. Zhang S.P., Bandler R., and Carrive P. Flight and immobility evoked by excitatory amino acid microinjection within distinct parts of the subtentorial midbrain periaqueductal gray of the cat. Brain Res 520 (1990) 73-82