Developmental changes in submucosal nitrergic neurons in the porcine distal colon

Journal of Pediatric Surgery

Volumn 41, Issue 5, 2006, Pages 1029-1035

  Montedonico, Sandra ^a   Paran, Thambipillai Sri ^a   Pirker, Martina ^a   Rolle, Udo ^a   Puri, Prem ^a  

^a OUR LADY S CHILDREN S HOSPITAL   (Ireland)

Author keywords

Distal colon; Enteric nervous system; Ganglia density; Ganglion cell number; Ganglion cells size; Nitrergic innervation; Porcine colon; Whole mount preparation

Indexed keywords

REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE;

ADULTHOOD; ANIMAL TISSUE; ARTICLE; AUTONOMIC NERVOUS SYSTEM; CELL DENSITY; CONTROLLED STUDY; CYTOPLASM; DESCENDING COLON; FETUS; GESTATIONAL AGE; HISTOCHEMISTRY; MORPHOLOGY; MORPHOMETRICS; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NEWBORN; NITRERGIC NERVE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; STATISTICAL SIGNIFICANCE; SWINE;

AGE FACTORS; ANIMALS; CELL COUNT; COLON; INTESTINAL MUCOSA; NITRERGIC NEURONS; SWINE;

EID: 33646134614     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpedsurg.2005.12.063     Document Type: Article

References (23)

1. Meier-Ruge W. Uber ein Erkrankungsbild des Colon mit Hirschsprung-Symptomatik. Vehr Dtsch Ges Pathol 55 (1971) 506-510
2. Meier-Ruge W., Gambazzi F., Kaufeler R.E., et al. The neuropathological diagnosis of neuronal intestinal dysplasia (NID B). Eur J Pediatr Surg 4 (1994) 267-273
3. Meier-Ruge W.A., Bronnimann P.B., Gambazzi F., et al. Histopathological criteria for intestinal neuronal dysplasia of the submucosal plexus (type B). Virchows Arch 426 (1995) 549-556
4. Koletzko S., Jesch I., Faus-Kebetaler T., et al. Rectal biopsy for diagnosis of intestinal neuronal dysplasia in children: a prospective multicentre study on interobserver variation and clinical outcome. Gut 44 (1999) 853-861
5. Kapur R.P. Neuronal dysplasia: a controversial pathological correlate of intestinal pseudo-obstruction. Am J Med Genet A 122 (2003) 287-293
6. Rolle U., Nemeth L., and Puri P. Nitrergic innervation of the normal gut and in motility disorders of childhood. J Pediatr Surg 37 (2002) 551-567
7. Bult H., Boeckxstaens G.E., Pelckmans P.A., et al. Nitric oxide as an inhibitory non-adrenergic non-cholinergic neurotransmitter. Nature 345 (1990) 346-347
8. Wester T., O'Briain D.S., and Puri P. Notable postnatal alterations in the myenteric plexus of normal human bowel. Gut 44 (1999) 666-674
9. Brown D.R., and Timmermans J.P. Lessons from the porcine enteric nervous system. Neurogastroenterol Motil 16 Suppl 1 (2004) 50-54
10. Kararli T.T. Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals. Biopharm Drug Dispos 16 (1995) 351-380
11. Wester T., O'Briain S., and Puri P. Morphometric aspects of the submucous plexus in whole-mount preparations of normal human distal colon. J Pediatr Surg 33 (1998) 619-622
12. Zhou Y., Tan C.K., and Ling E.A. Distribution of NADPH-diaphorase and nitric oxide synthase-containing neurons in the intramural ganglia of guinea pig urinary bladder. J Anat 190 Pt 1 (1997) 135-145
13. Pirker M.E., Montedonico S., Rolle U., et al. Regional differences in nitrergic neuronal density in the developing porcine urinary bladder. Pediatr Surg Int 21 (2005) 161-168
14. Gabella G. Neuron size and number in the myenteric plexus of the newborn and adult rat. J Anat 109 (1971) 81-95
15. Coerdt W., Michel J.S., Rippin G., et al. Quantitative morphometric analysis of the submucous plexus in age-related control groups. Virchows Arch 444 (2004) 239-246
16. Smith V.V. Intestinal neuronal density in childhood: a baseline for the objective assessment of hypo- and hyperganglionosis. Pediatr Pathol 13 (1993) 225-237
17. Bagyanszki M., Roman V., and Fekete E. Quantitative distribution of NADPH-diaphorase-positive myenteric neurons in different segments of the developing chicken small intestine and colon. J Histochem 32 (2000) 679-684
18. Roman V., Krecsmarik M., Bagyanszki M., et al. Evaluation of the total number of myenteric neurons in the developing chicken gut using cuprolinic blue histochemical staining and neurofilament immunocytochemistry. Histochem Cell Biol 116 (2001) 241-246
19. Wolfensohn S.L.M. Handbook of laboratory animal management and welfare (2003), Blackwell, Oxford, UK
20. Smith B. Pre- and postnatal development of the ganglion cells of the rectum and its surgical implications. J Pediatr Surg 3 (1968) 386-391
21. Gabella G. Size of neurons and glial cells in the intramural ganglia of the hypertrophic intestine of the guinea-pig. J Neurocytol 13 (1984) 73-84
22. Montedonico S., Acevedo S., and Fadda B. Clinical aspects of intestinal neuronal dysplasia. J Pediatr Surg 37 (2002) 1772-1774
23. Gillick J., Tazawa H., and Puri P. Intestinal neuronal dysplasia: results of treatment in 33 patients. J Pediatr Surg 36 (2001) 777-779