Results from an observational trial: Digital epiluminescence microscopy follow-up of atypical nevi increases the sensitivity and the chance of success of conventional dermoscopy in detecting melanoma

Journal of Investigative Dermatology

Volumn 126, Issue 5, 2006, Pages 980-985

  Haenssle, Holger A ^a   Krueger, Ullrich ^a   Vente, Claudia ^a   Thoms, Kai Martin ^a   Bertsch, Hans P ^a   Zutt, Markus ^a   Rosenberger, Albert ^a   Neumann, Christine ^a   Emmert, Steffen ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER RISK; CHILD; CLINICAL EXAMINATION; CLINICAL TRIAL; DIAGNOSTIC VALUE; DIGITAL EPILUMINESCENCE MICROSCOPY; DIGITAL IMAGING; EPILUMINESCENCE MICROSCOPY; FAMILIAL CANCER; FEMALE; FOLLOW UP; HIGH RISK PATIENT; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MELANOMA; NEVUS; OBSERVATIONAL STUDY; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHILD; CHILD, PRESCHOOL; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; MELANOMA; MICROSCOPY; MIDDLE AGED; NEVUS, PIGMENTED; PROGNOSIS; PROSPECTIVE STUDIES; RISK FACTORS; SENSITIVITY AND SPECIFICITY; SKIN NEOPLASMS;

EID: 33646125435     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5700119     Document Type: Article

References (19)

1. Argenziano G (2005) The impact of dermoscopy on the management of pigmented skin lesions: the role of follow-up. J Am Acad Dermatol 52:178-80
2. Ascierto PA, Palmieri G, Celentano E, Parasole R, Caraco C, Daponte A et al. (2000) Sensitivity and specificity of epiluminescence microscopy: evaluation on a sample of 2731 excised cutaneous pigmented lesions. The Melanoma Cooperative Study. Br J Dermatol 142:893-8
3. Binder M, Kittler H, Seeber A, Steiner A, Pehamberger H, Wolff K (1998) Epiluminescence microscopy-based classification of pigmented skin lesions using computerized image analysis and an artificial neural network. Melanoma Res 8:261-6
4. Braun RP, Lemonnier E, Guillod J, Skaria A, Salomon D, Saurat JH (1998) Two types of pattern modification detected on the follow-up of benign melanocytic skin lesions by digitized epiluminescence microscopy. Melanoma Res 8:431-7
5. Breslow A (1980) Prognosis in cutaneous melanoma: tumor thickness as a guide to treatment. Pathol Annu 15:1-22
6. Carli P, de Giorgi V, Chiarugi A, Nardini P, Weinstock MA, Crocetti E et al. (2004a) Addition of dermoscopy to conventional naked-eye examination in melanoma screening: a randomized study. J Am Acad Dermatol 50:683-9
7. Carli P, de Giorgi V, Crocetti E, Mannone F, Massi D, Chiarugi A et al. (2004b) Improvement of malignant/benign ratio in excised melanocytic lesions in the "dermoscopy era": a retrospective study 1997-2001. Br J Dermatol 150:687-92
8. Carli P, de Giorgi V, Giannotti B (2003) Why digital follow-up of dermoscopically equivocal pigmented lesions should be discouraged. Br J Dermatol 148:1272-3
9. Carli P, Massi D, de Giorgi V, Giannotti B (2002) Clinically and dermoscopically featureless melanoma: when prevention fails. J Am Acad Dermatol 46:957-9
10. Greene MH (1999) The genetics of hereditary melanoma and nevi. 1998 update. Cancer 86:2464-77
11. Haenssle HA, Vente C, Bertsch HP, Rupprecht R, Abuzahra F, Junghans V et al. (2004) Results of a surveillance programme for patients at high risk of malignant melanoma using digital and conventional dermoscopy. Eur J Cancer Prev 13:133-8
12. Kelly JW, Yeatman JM, Regalia C, Mason G, Henham AP (1997) A high incidence of melanoma found in patients with multiple dysplastic naevi by photographic surveillance. Med J Aust 167:191-4
13. Kittler H, Binder M (2001) Risks and benefits of sequential imaging of melanocytic skin lesions in patients with multiple atypical nevi. Arch Dermatol 137:1590-5
14. Kittler H, Pehamberger H, Wolff K, Binder M (2000) Follow-up of melanocytic skin lesions with digital epiluminescence microscopy: patterns of modifications observed in early melanoma, atypical nevi, and common nevi. J Am Acad Dermatol 43:467-76
15. Menzies SW, Gutenev A, Avramidis M, Batrac A, McCarthy WH (2001) Short-term digital surface microscopic monitoring of atypical or changing melanocytic lesions. Arch Dermatol 137:1583-9
16. Pehamberger H, Steiner A, Wolff K (1987) In vivo epiluminescence microscopy of pigmented skin lesions. I. Pattern analysis of pigmented skin lesions. J Am Acad Dermatol 17:571-83
17. Robinson JK, Nickoloff BJ (2004) Digital epiluminescence microscopy monitoring of high-risk patients. Arch Dermatol 140:49-56
18. Schiffner R, Schiffner-Rohe J, Landthaler M, Stolz W (2003) Long-term dermoscopic follow-up of melanocytic naevi: clinical outcome and patient compliance. Br J Dermatol 149:79-86
19. Tucker MA, Halpern A, Holly EA, Hartge P, Elder DE, Sagebiel RW et al. (1997) Clinically recognized dysplastic nevi. A central risk factor for cutaneous melanoma. JAMA 277:1439-44