A short report on highlights of worldwide development of RIX4414: A Singaporean experience

Vaccine

Volumn 24, Issue 18, 2006, Pages 3782-3783

  Phua, K B ^a   Quak, S H ^b   Emmanuel, S ^c   Goh, P S C ^d   Han, H H ^d   Hardt, K ^e   Bock, H L ^d   De Vos, B ^e  

^a KK WOMEN'S AND CHILDREN'S HOSPITAL   (Singapore)

^b NATIONAL UNIVERSITY HOSPITAL   (Singapore)

^c NATIONAL HEALTHCARE GROUP POLYCLINICS   (Singapore)

^d Tampines Polyclinic ^*  (Singapore)

^e GLAXOSMITHKLINE BIOLOGICALS   (Belgium)

Author keywords

Attenuated human rotavirus vaccine; Phase II clinical trial

Indexed keywords

DIPHTHERIA PERTUSSIS TETANUS VACCINE; HAEMOPHILUS INFLUENZAE TYPE B VACCINE; INACTIVATED VACCINE; LIVE VACCINE; PLACEBO; POLIOMYELITIS VACCINE; ROTAVIRUS VACCINE;

ACTIVE IMMUNIZATION; ANOREXIA; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COUGHING; DIARRHEA; DOUBLE BLIND PROCEDURE; DRUG TOLERABILITY; FEVER; HUMAN; HUMAN ROTAVIRUS; IMMUNOGENICITY; INFANT; IRRITABILITY; MAJOR CLINICAL STUDY; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEROCONVERSION; SIDE EFFECT; SINGAPORE; VIRUS INFECTION; VOMITING;

ANTIBODIES, VIRAL; DOUBLE-BLIND METHOD; HUMANS; INFANT; ROTAVIRUS; ROTAVIRUS VACCINES; SINGAPORE; VACCINES, ATTENUATED;

EID: 33646123517     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2006.03.040     Document Type: Article

References (3)

1. Parashar U.D., Hummelman E.G., Bresee J.S., Miller M.A., and Glass R.I. Global illness and deaths caused by rotavirus disease in children. Emerg Infect Dis 9 (2003) 565-572
2. Bresee J., Fang Z.-Y., Wang B., Nelson E.A.S., Tam J., Soenarto Y., et al. First report from the Asian Rotavirus Surveillance Network. Emerg Infect Dis 10 6 (2004) 988-995
3. Phua KB, Quak SH, Lee BW, Emmanuel SC, Goh P, Han HH, et al. Evaluation of RIX4414, a live attenuated rotavirus vaccine, in a randomized, double-blind, placebo-controlled phase 2 trial involving 2464 Singapoore infants. J Infect Dis 2005; 152(suppl 1):S6-16.