Slow-binding human serine racemase inhibitors from high-throughput screening of combinatorial libraries

Journal of Medicinal Chemistry

Volumn 49, Issue 8, 2006, Pages 2388-2397

  Dixon, Seth M ^a   Li, Pu ^a   Liu, Ruiwu ^a   Wolosker, Herman ^b   Lam, Kit S ^a   Kurth, Mark J ^a   Toney, Michael D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; HISTIDINE; HUMAN SERINE RACEMASE INHIBITOR; HYDROCINNAMIC ACID; PEPTIDE LIBRARY; RACEMASE; RESIN; UNCLASSIFIED DRUG;

ARTICLE; COMBINATORIAL CHEMISTRY; COMBINATORIAL LIBRARY; ENZYME INHIBITION; FLUORESCENCE; HIGH THROUGHPUT SCREENING; PHARMACOPHORE;

COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG EVALUATION, PRECLINICAL; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; KINETICS; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PEPTIDE LIBRARY; PEPTIDES; PROTEIN BINDING; RACEMASES AND EPIMERASES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33646111450     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm050701c     Document Type: Article

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