Analysis of intrahepatic lymphocyte subsets in a transgenic mouse model of immune-mediated hepatocarcinogenesis

Journal of Experimental and Clinical Cancer Research

Volumn 25, Issue 1, 2006, Pages 55-57

  Nakamoto, Yasunari ^a   Kaneko, S ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

Chronic hepatitis; Hepatocellular carcinoma; Intrahepatic lymphocytes; Transgenic mice

Indexed keywords

HEPATITIS B SURFACE ANTIGEN;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CANCER MODEL; CHRONIC HEPATITIS; CONTROLLED STUDY; CYTOTOXIC LYMPHOCYTE; IMMUNE MEDIATED INJURY; INFLAMMATION; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER CELL DAMAGE; LIVER DISEASE; LYMPHOCYTE; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; TRANSGENIC MOUSE; VIRUS HEPATITIS;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CD8-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; HEPATITIS; HEPATITIS, VIRAL, HUMAN; HUMANS; INFLAMMATION; LIVER; LIVER NEOPLASMS; MACROPHAGES; MICE; MICE, TRANSGENIC; MONOCYTES; T-LYMPHOCYTES, CYTOTOXIC;

EID: 33646110250     PISSN: 03929078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Di Bisceglie A.M.: Hepatitis C and hepatocellular carcinoma. Hepatology 26: 34S-38S, 1997.
2. Ikeda K., Saitoh S., Suzuki Y., et al.: Disease progression and hepatocellular carcinogenesis in patients with chronic viral hepatitis: a prospective observation of 2215 patients. J. Hepatol. 28: 930-938, 1998.
3. Chisari F.V., Klopchin K., Moriyama T., et al.: Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice. Cell 59: 1145-1156, 1989.
4. Nakamoto Y., Guidotti L.G., Kuhlen C.V., Fowler, P., Chisari, F. V.: Immune pathogenesis of hepatocellular carcinoma. J. Exp. Med. 188: 341-350, 1998.
5. Chisari F.V., Filippi P., McLachlan A., et al.: Expression of hepatitis B virus large envelope polypeptide inhibits hepatitis B surface antigen secretion in transgenic mice. J. Virol. 60: 880-887, 1986.
6. Moriyama T., Guilhot S., Klopchin K., et al.: Immunobiology and pathogenesis of hepatocellular injury in hepatitis B virus transgenic mice. Science 248: 361-364, 1990.
7. Ando K., Moriyama T., Guidotti L.G., et al.: Mechanisms of class I restricted immunopathology. A transgenic mouse model of fulminant hepatitis. J. Exp. Med. 178: 1541-1554, 1993.
8. Nakamoto Y., Suda T., Momoi T., Kaneko S.: Different procarcinogenic potentials of lymphocyte subsets in a transgenic mouse model of chronic hepatitis B. Cancer Res. 64: 3326-3333, 2004.