Hypersexuality in two patients with epilepsy treated with lamotrigine

Epilepsy and Behavior

Volumn 8, Issue 3, 2006, Pages 663-665

  Grabowska Grzyb, Ałbena ^a   Nagańska, Ewa ^a,b   Wolańczyk, Tomasz ^c  

^a Centre for Postgraduate Education   (Poland)

^b MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

^c MEDICAL UNIVERSITY OF WARSAW   (Poland)

Author keywords

Epilepsy; Hypersexuality; Lamotrigine

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; GABAPENTIN; LAMOTRIGINE; OXCARBAZEPINE;

ADD ON THERAPY; ADULT; ARTICLE; BRAIN DAMAGE; CASE REPORT; DISEASE PREDISPOSITION; DRUG BLOOD LEVEL; DRUG DOSE REDUCTION; DRUG WITHDRAWAL; FRONTAL LOBE EPILEPSY; HUMAN; HYPERSEXUALITY; HYPOMANIA; MALE; MENTAL DISEASE; SEXUAL BEHAVIOR; SEXUAL SATISFACTION; TEMPORAL LOBE EPILEPSY;

ANTICONVULSANTS; EPILEPSY, FRONTAL LOBE; EPILEPSY, TEMPORAL LOBE; HUMANS; LIBIDO; MALE; MIDDLE AGED; SEXUAL DYSFUNCTION, PHYSIOLOGICAL; TRIAZINES;

EID: 33646102215     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2006.01.005     Document Type: Article

References (15)

1. Leach M.J., Marden C.M., and Miller A.A. Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action. Epilepsia 27 (1986) 490-497
2. Rambeck B., and Wolf P. Lamotrigine clinical pharmacokinetics. Clin Pharmacokinet 25 (1993) 433-443
3. Wolańczyk T, Kaszuba D, Jóźwik A, Moskwa M. Lamotrigine effect on depression and anxiety in patients with epilepsy: a preliminary study. Paper presented at: American Psychiatric Association, 156th Annual Meeting, San Francisco, May 17-22, 2003; New Research Abstracts No. 234. p. 87.
4. Herzog A.G., Drislane F.W., Schomer D.L., et al. Differential effects of antiepileptic drugs on sexual function and reproductive hormones in men with epilepsy: interim analysis of a comparison between lamotrigine and enzyme-inducing antiepileptic drugs. Epilepsia 45 (2004) 764-768
5. Uitti R.J., Tanner C.M., Rajput A.H., Goetz C.G., Klawans H.L., and Thiessen B. Hypersexuality with antiparkinsonian therapy. Clin Neuropharmacol 12 (1989) 375-383
6. Kanovsky P., Bares M., Pohanka M., and Rektor I. Penile erections and hypersexuality induced by pergolide treatment in advanced, fluctuating Parkinson's disease. J Neurol 249 (2002) 112-114
7. Chollet C.A., and Andreatini R. Effect of bupropion on sexual dysfunction induced by fluoxetine: a case report of hypersexuality. J Clin Psychiatry 64 (2003) 1268-1269
8. Korpelainen J.T., Hiltunen P., and Myllyla V.V. Moclobemide-induced hypersexuality in patients with stroke and Parkinson's disease. Clin Neuropharmacol 21 (1998) 251-254
9. Myers W.C., and Carrera III F. Carbamazepine-induced mania with hypersexuality in a 9-year-old boy. Am J Psychiatry 146 (1989) 400
10. Barth R.J., and Kinder B.N. The mislabeling of sexual impulsivity. J Sex Marital Ther 13 (1987) 15-23
11. Temin P.A. Mukhin KIu{raising sign} [Sex disorders in men with epilepsy]. Zh Nevropatol Psikhiatr 91 6 (1991) 47-50
12. Morrell M.J. Sexual dysfunction in epilepsy. Epilepsia 32 Suppl. 6 (1991) S38-S45
13. Bauer J., Stoffel-Wagner B., Flugel D., et al. Serum androgens return to normal after temporal lobe epilepsy surgery in men. Neurology 26 55 (2000) 820-824
14. Edwards H.E., Burnham W.M., and MacLusky N.J. Partial and generalized seizures affect reproductive physiology differentially in the male rat. Epilepsia 40 (1999) 1490-1498
15. Husain A.M., Carwile S.T., Miller P.P., and Radtke R.A. Improved sexual function in three men taking lamotrigine for epilepsy. South Med J 93 (2000) 335-336