A randomized, double-blind, placebo-controlled trial of photopheresis in systemic sclerosis

Journal of the American Academy of Dermatology

Volumn 54, Issue 5, 2006, Pages 793-799

  Knobler, Robert M ^a   French, Lars E ^b   Kim, Youn ^c   Bisaccia, Emil ^d   Graninger, Winfried ^e   Nahavandi, Hesam ^a   Strobl, Frank J ^f   Keystone, Edward ^g   Mehlmauer, Marilyn ^h   Rook, Alain H ⁱ   Braverman, Irwin ^j  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MORRISTOWN MEMORIAL HOSPITAL   (United States)

^e MEDICAL UNIVERSITY OF GRAZ   (Austria)

^f Therakos Inc   (United States)

^g UNIVERSITY OF TORONTO   (Canada)

^h HUNTINGTON MEMORIAL HOSPITAL   (United States)

ⁱ HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^j YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

METHOXSALEN; UVADEX;

ADULT; ANALYTIC METHOD; ARTICLE; BODY REGIONS; CANADA; CLINICAL ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; EUROPE; FEMALE; HUMAN; JOINT CONTRACTURE; MALE; PRIORITY JOURNAL; PUVA; RANDOMIZED CONTROLLED TRIAL; SAMPLE SIZE; SCLERODERMA; SCORING SYSTEM; STATISTICAL SIGNIFICANCE; SYSTEMIC SCLEROSIS; UNITED STATES;

ADULT; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MIDDLE AGED; PHOTOPHERESIS; PLACEBOS; SCLERODERMA, SYSTEMIC; TREATMENT OUTCOME;

EID: 33646093984     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaad.2005.11.1091     Document Type: Article

References (22)

1. Perez M.I., and Kohn S.R. Systemic sclerosis. J Am Acad Dermatol 28 (1993) 525-547
2. Barnet A.J., Miller M., and Littlejohn G.O. The diagnosis and classification of scleroderma (systemic sclerosis). Postgrad Med J 64 (1998) 121-125
3. Pope J.E. Treatment of systemic sclerosis. Rheum Dis Clin North Am 22 (1996) 893-907
4. Rook A.H., Freundlich B., Jegasothy B.V., Perez M.I., Barr W.G., Jimenez S.A., et al. Treatment of systemic sclerosis with extracorporeal photochemotherapy. Results of a multicenter trial. Arch Dermatol 128 (1992) 337-346
5. Rook A.H., Suchin K.R., Kao D.M., Yoo E.K., Macey W.H., De Nardo B.J., et al. Photopheresis: clinical applications and mechanism of action. J. Invest Dermatol Symp Proc 4 (1999) 85-90
6. White B., Bauer E.A., Goldsmith L.A., Hochberg M.C., Ratz L.M., Korn J.H., et al. Guidelines for clinical trials in systemic sclerosis (scleroderma). I. Disease-modifying interventions. The American College of Rheumatology Committee on design and outcomes in clinical trails in systemic sclerosis. Arthritis Rheum 38 (1995) 351-360
7. Edelson R., Berger C., Gasparro F., Jegasothy B., Heald P., Wintroub B., et al. Treatment of cutaneous T-cell lymphoma by extracorporeal photochemotherapy. Preliminary results. N Engl J Med 316 (1987) 297-303
8. Kahaleh M.B., Sultany G.L., Smith E.A., Huffsutter J.E., Loadholt C.B., and Le Roy E.C. A modified scleroderma skin scoring method. Clin Exp Rheumatol 4 (1986) 367-369
9. Drake L.A., Dinehart S.M., Farmer E.R., Goltz R.W., Graham G.F., Hordinsky M.K., et al. Guidelines of care for scleroderma and sclerodermoid disorders. American Academy of Dermatology. J Am Acad Dermatol 35 (1996) 609-614
10. Enomoto D.N.H., Mekkes J.R., Bossuyt P.M.M., Yong S.L., Out T.A., Hoekzema R., et al. Treatment of patients with systemic sclerosis with extracorporeal photochemotherapy (photopheresis). J Am Acad Dermatol 41 (1999) 915-922
11. Heald P., Rook A., Perez M., Wintroub B., Knobler R., Jegasothy B., et al. Treatment of erythrodermic cutaneous T-cell lymphoma with extracorporeal photochemotherapy. J Am Acad Dermatol 27 (1992) 427-433
12. Gottlieb S.L., Wolfe J.T., Fox F.E., De Nardo B.J., Macey W.H., Bromley P.G., et al. Treatment of cutaneous T-cell lymphoma with extracorporeal photopheresis monotherapy and in combination with recombinant interferon alfa: a 10-year experience at a single institution. J Am Acad Dermatol 35 (1996) 946-957
13. Zic J.A., Stricklin G.P., Greer J.P., Kinney M.C., Shyr Y., Wilson D.C., et al. Long-term follow-up of patients with cutaneous T-cell lymphoma treated with extracorporeal photochemotherapy. J Am Acad Dermatol 35 (1996) 935-945
14. Duvic M., Lemak N.A., Redman J.R., Eitel P.J., Tucker S.L., Cabanillas F.F., et al. Combined modality therapy for cutaneous T-cell lymphoma. J Am Acad Dermatol 34 (1996) 1022-1029
15. Armus S., Keyes B., Cahill C., Berger C., Crater D., Scarborough D., et al. Photopheresis for the treatment of cutaneous T-cell lymphoma. J Am Acad Dermatol 23 (1990) 898-902
16. Girardi M., Heald P., and Tigelaar R.E. Specific suppression of lupus-like graft-versus-host-disease using extracorporeal photochemical attenuation of effector lymphocytes. J Invest Dermatol 104 (1995) 177-182
17. Perez M.I., Edelson R.L., John L., Laroche L., and Berger C.L. Inhibition of antiskin allograft immunity induced by infusions with photoinactivated effector T lymphocytes (PET cells). Yale J Biol Med 62 (1989) 595-609
18. White B. Pathogenesis of systemic sclerosis. Rheum Dis Clin North Am 22 (1996) 695-708
19. Kulozik M., Hogg A., Lankat-Buttgereit B., and Krieg T. Co-localization of transforming growth factor beta 2 with alpha 1 (I) procollagen mRNA in tissue sections of patients with systemic sclerosis. J Clin Invest 86 (1990) 917-922
20. Smith E.A., and Le Roy E.C. A possible role for transforming growth factor-beta in systemic sclerosis. J Invest Dermatol 95 (1990) 1258-1273
21. French L.E., Lessin S.R., Addya K., Denardo B., Margolis D.J., Leonard D.G., et al. Identification of clonal T cells in the blood of patients with systemic sclerosis: positive correlation with response to photopheresis. Arch Dermatol 137 (2001) 1309-1313
22. French L.E., Alcindor T., Shapiro M., McGinnis K.S., Margolis D.J., Porter D., et al. Identification of amplified clonal T cell populations in the blood of patients with chronic graft-versus-host disease: positive correlation with response to photopheresis. Bone Marrow Transplant 30 (2002) 509-515