메뉴 건너뛰기




Volumn 17, Issue 1, 2006, Pages 75-80

Plasma kinetics of procarbazine and azo-procarbazine in humans

Author keywords

Azo procarbazine; Human; Pharmacokinetics; Procarbazine

Indexed keywords

AZOPROCARBAZINE; DRUG METABOLITE; ONDANSETRON; PROCARBAZINE; UNCLASSIFIED DRUG;

EID: 33646089870     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.cad.0000181591.85476.aa     Document Type: Article
Times cited : (15)

References (27)
  • 1
    • 0010925690 scopus 로고    scopus 로고
    • Nonclassic alkylating agents
    • Chabner BA, Longo DL (editors): Philadelphia: Lippincott Williams & Wilkins
    • Friedman HS, Averbuch SD, Kurtzberg J. Nonclassic alkylating agents. In: Chabner BA, Longo DL (editors): Cancer chemotherapy and biotherapy. 3rd ed. Philadelphia: Lippincott Williams & Wilkins; 2001. p. 415.
    • (2001) Cancer Chemotherapy and Biotherapy. 3rd Ed. , pp. 415
    • Friedman, H.S.1    Averbuch, S.D.2    Kurtzberg, J.3
  • 2
    • 0037567428 scopus 로고    scopus 로고
    • Standard and increased-dose BEACOPP chemotherapy compared with COPPABVD for advanced Hodgkin's disease
    • Diehl V, Franklin J, Pfreundschuh M, Lathan B, Paulus U, Hasenclever D, et al. Standard and increased-dose BEACOPP chemotherapy compared with COPPABVD for advanced Hodgkin's disease. N Engl J Med 2003; 348:2386-2395.
    • (2003) N Engl J Med , vol.348 , pp. 2386-2395
    • Diehl, V.1    Franklin, J.2    Pfreundschuh, M.3    Lathan, B.4    Paulus, U.5    Hasenclever, D.6
  • 3
    • 4143092591 scopus 로고    scopus 로고
    • Procarbazine in haematology: An old drug with a new life?
    • Massoud M, Armand JP, Ribrag V. Procarbazine in haematology: an old drug with a new life? Eur J Cancer 2004; 40:1924-1927.
    • (2004) Eur J Cancer , vol.40 , pp. 1924-1927
    • Massoud, M.1    Armand, J.P.2    Ribrag, V.3
  • 4
    • 0024597191 scopus 로고
    • Cytotoxicity and DNA damage caused by the azoxy metabolites of procarbazine in L1210 tumor cells
    • Erikson JM, Tweedie DJ, Ducore JM, Prough RA. Cytotoxicity and DNA damage caused by the azoxy metabolites of procarbazine in L1210 tumor cells. Cancer Res 1989; 49:127-133.
    • (1989) Cancer Res , vol.49 , pp. 127-133
    • Erikson, J.M.1    Tweedie, D.J.2    Ducore, J.M.3    Prough, R.A.4
  • 5
    • 0014721603 scopus 로고
    • Metabolism of an antineoplastic methylhydrazine derivative in a P815 mouse neoplasm
    • Kreis W. Metabolism of an antineoplastic methylhydrazine derivative in a P815 mouse neoplasm. Cancer Res 1970; 30:82-89.
    • (1970) Cancer Res , vol.30 , pp. 82-89
    • Kreis, W.1
  • 8
    • 0032784651 scopus 로고    scopus 로고
    • Metabolic activation of dacarbazine by human cytochromes p450: The role of CYP1A1, CYP1A2, and CYP2E1
    • Reid JM, Kuffel MJ, Miller JK, Rios R, Ames MM. Metabolic activation of dacarbazine by human cytochromes p450: the role of CYP1A1, CYP1A2, and CYP2E1. Clin Cancer Res 1999; 5:2192-2197.
    • (1999) Clin Cancer Res , vol.5 , pp. 2192-2197
    • Reid, J.M.1    Kuffel, M.J.2    Miller, J.K.3    Rios, R.4    Ames, M.M.5
  • 9
    • 0038520096 scopus 로고    scopus 로고
    • Metabolic activation of temozolomide measured in vivo using positron emission tomography
    • Saleem A, Brown GD, Brady F. Metabolic activation of temozolomide measured in vivo using positron emission tomography. Cancer Res 2003; 63:2409-2415.
    • (2003) Cancer Res , vol.63 , pp. 2409-2415
    • Saleem, A.1    Brown, G.D.2    Brady, F.3
  • 11
    • 0021080920 scopus 로고
    • The mitochondrial metabolism of 1,2-disubstituted hydrazines, procarbazine and 1,2-dimethylhydrazine
    • Coomes MW, Prough RA. The mitochondrial metabolism of 1,2-disubstituted hydrazines, procarbazine and 1,2-dimethylhydrazine. Drug Metab Disp 1983; 11:550-555.
    • (1983) Drug Metab Disp , vol.11 , pp. 550-555
    • Coomes, M.W.1    Prough, R.A.2
  • 12
    • 0018638857 scopus 로고
    • Oxidative metabolism of N-isopropyl-α-(2-methylhydrazino)-p-toluamide hydrochloride (procarbazine) by rat liver microsomes
    • Dunn DL, Lubet RA, Prough RA. Oxidative metabolism of N-isopropyl-α-(2-methylhydrazino)-p-toluamide hydrochloride (procarbazine) by rat liver microsomes. Cancer Res 1979; 39:4555-4563.
    • (1979) Cancer Res , vol.39 , pp. 4555-4563
    • Dunn, D.L.1    Lubet, R.A.2    Prough, R.A.3
  • 13
    • 0022672080 scopus 로고
    • Oxidative metabolism of some hydrazine derivatives by rat liver and lung tissue fractions
    • Erikson JM, Prough RA. Oxidative metabolism of some hydrazine derivatives by rat liver and lung tissue fractions. J Biochem Toxicol 1986; 1:41-52.
    • (1986) J Biochem Toxicol , vol.1 , pp. 41-52
    • Erikson, J.M.1    Prough, R.A.2
  • 14
    • 0017834692 scopus 로고
    • Metabolic activation of procarbazine
    • Weinkam RJ, Shiba DA. Metabolic activation of procarbazine. Life Sci 1978; 22:937-946.
    • (1978) Life Sci , vol.22 , pp. 937-946
    • Weinkam, R.J.1    Shiba, D.A.2
  • 15
    • 0021368325 scopus 로고
    • Major isozymes of rat liver microsomal cytochrome P-450 involved in the N-oxidation of N-isopropyl-α-(2-methylazo)-p-toluamide, the azo derivative of procarbazine
    • Prough RA, Brown MI, Dannan GA, Guengerich FP. Major isozymes of rat liver microsomal cytochrome P-450 involved in the N-oxidation of N-isopropyl-α-(2-methylazo)-p-toluamide, the azo derivative of procarbazine. Cancer Res 1984; 44:543-548.
    • (1984) Cancer Res , vol.44 , pp. 543-548
    • Prough, R.A.1    Brown, M.I.2    Dannan, G.A.3    Guengerich, F.P.4
  • 16
    • 0018935010 scopus 로고
    • Oxidative metabolism of N-isopropyl-α-(2-methylazo)-p-toluamide (azoprocarbazine) by rodent liver microsomes
    • Wiebkin P, Prough RA. Oxidative metabolism of N-isopropyl-α-(2-methylazo)-p-toluamide (azoprocarbazine) by rodent liver microsomes. Cancer Res 1980; 40:3524-3529.
    • (1980) Cancer Res , vol.40 , pp. 3524-3529
    • Wiebkin, P.1    Prough, R.A.2
  • 17
    • 0021992540 scopus 로고
    • Metabolic activation of the terminal N-methyl group of N-isopropyl-α-(2-methylhydrazino)-p-toluamide hydrochloride (procarbazine)
    • Moloney SJ, Wiebkin P, Cummings SW, Prough RA. Metabolic activation of the terminal N-methyl group of N-isopropyl-α-(2-methylhydrazino)-p-toluamide hydrochloride (procarbazine). Carcinogenesis 1985; 6:397-401.
    • (1985) Carcinogenesis , vol.6 , pp. 397-401
    • Moloney, S.J.1    Wiebkin, P.2    Cummings, S.W.3    Prough, R.A.4
  • 18
    • 0014150038 scopus 로고
    • Distribution and excretion studies of procarbazine in animals and man
    • Schwartz DE, Bollag W, Obrecht P. Distribution and excretion studies of procarbazine in animals and man. Arzneimittelforschung 1967; 17:1389-1393.
    • (1967) Arzneimittelforschung , vol.17 , pp. 1389-1393
    • Schwartz, D.E.1    Bollag, W.2    Obrecht, P.3
  • 19
    • 0026646764 scopus 로고
    • Isolation, purification, and characterization of two new chemical decomposition products of methylazoxyprocarbazine
    • Swaffar DS, Harker WG, Pomerantz SC, Lim HK, Yost GS. Isolation, purification, and characterization of two new chemical decomposition products of methylazoxyprocarbazine. Drug Met Dispos 1992; 20:632-642.
    • (1992) Drug Met Dispos , vol.20 , pp. 632-642
    • Swaffar, D.S.1    Harker, W.G.2    Pomerantz, S.C.3    Lim, H.K.4    Yost, G.S.5
  • 20
    • 0026968941 scopus 로고
    • Non-enzymatic activation of procarbazine to active cytotoxic species
    • Swaffar DS, Pomerantz SC, Harker WG, Yost GS. Non-enzymatic activation of procarbazine to active cytotoxic species. Oncol Res 1992; 4:49-58.
    • (1992) Oncol Res , vol.4 , pp. 49-58
    • Swaffar, D.S.1    Pomerantz, S.C.2    Harker, W.G.3    Yost, G.S.4
  • 21
    • 33646095410 scopus 로고
    • Cytosolic enzymes mediate the metabolism of the azoxy isomers of the anticancer drug, procarbazine
    • Tweedie DJ, Erikson JM, Prough RA. Cytosolic enzymes mediate the metabolism of the azoxy isomers of the anticancer drug, procarbazine. Proc Am Ass Cancer Res 1987; 28:521.
    • (1987) Proc Am Ass Cancer Res , vol.28 , pp. 521
    • Tweedie, D.J.1    Erikson, J.M.2    Prough, R.A.3
  • 22
    • 0024549468 scopus 로고
    • Methylazoxyprocarbazine, the active metabolite responsible for anticancer activity of procarbazine against L1210 leukemia
    • Swaffar DS, Horstman MG, Jaw J-Y, Thrall BD, Meadows GG, Harker WG, et al. Methylazoxyprocarbazine, the active metabolite responsible for anticancer activity of procarbazine against L1210 leukemia. Cancer Res 1989; 49:2442-2447.
    • (1989) Cancer Res , vol.49 , pp. 2442-2447
    • Swaffar, D.S.1    Horstman, M.G.2    Jaw, J.-Y.3    Thrall, B.D.4    Meadows, G.G.5    Harker, W.G.6
  • 23
    • 0344665700 scopus 로고    scopus 로고
    • Determination of procarbazine in human plasma by liquid chromatography with electrospray ionization mass spectrometry
    • He X, Batchelor TT, Grossmann S, Supko JG. Determination of procarbazine in human plasma by liquid chromatography with electrospray ionization mass spectrometry. J Chromatogr B 2004; 799:281-291.
    • (2004) J Chromatogr B , vol.799 , pp. 281-291
    • He, X.1    Batchelor, T.T.2    Grossmann, S.3    Supko, J.G.4
  • 24
    • 33646119790 scopus 로고
    • On the metabolism of a cytostatic methylhydrazine derivative (Natulan)
    • 1965
    • Raaflaub J, Schwartz DE. (1965). On the metabolism of a cytostatic methylhydrazine derivative (Natulan). Experentia 1965; 21:44-45.
    • (1965) Experentia , vol.21 , pp. 44-45
    • Raaflaub, J.1    Schwartz, D.E.2
  • 25
    • 0009803192 scopus 로고
    • Some pharmacologic properties of a new antitumor agent N-isopropyl-β-(2-methylhydrazino)-p-toluamide, hydrochloride (NSC-77213)
    • Oliverío VT, Danham C, DeVita VT, Kelly MG. Some pharmacologic properties of a new antitumor agent N-isopropyl-β-(2-methylhydrazino)-p-toluamide, hydrochloride (NSC-77213). Cancer Chemother Rep 1964; 42:1-7.
    • (1964) Cancer Chemother Rep , vol.42 , pp. 1-7
    • Oliverío, V.T.1    Danham, C.2    DeVita, V.T.3    Kelly, M.G.4
  • 26
    • 0020264415 scopus 로고
    • Quantitative analysis of procarbazine, procarbazine metabolites and chemical degradation products with application to pharmacokinetic studies
    • Shiba DA, Weinkam RJ. Quantitative analysis of procarbazine, procarbazine metabolites and chemical degradation products with application to pharmacokinetic studies. J Chromatogr B 1982; 229:397-407.
    • (1982) J Chromatogr B , vol.229 , pp. 397-407
    • Shiba, D.A.1    Weinkam, R.J.2
  • 27
    • 0019141234 scopus 로고
    • Analysis of procarbazine and metabolites by gas chromatography-mass spectrometry
    • Gorsen RM, Weiss AJ, Manthei RW. Analysis of procarbazine and metabolites by gas chromatography-mass spectrometry. J Chromatogr 1980; 221:309-318.
    • (1980) J Chromatogr , vol.221 , pp. 309-318
    • Gorsen, R.M.1    Weiss, A.J.2    Manthei, R.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.