A role for interleukin-10 in the assessment of venous thromboembolism risk in injured patients

Journal of Trauma - Injury, Infection and Critical Care

Volumn 60, Issue 1, 2006, Pages 147-151

  Proctor, Mary C ^a   Sullivan, Vita ^b,c   Zajkowski, Paul ^a   Wolk, Seth W ^b   Pomerantz, Richard A ^b   Wakefield, Thomas W ^a   Greenfield, Lazar J ^a   Luchette, Fred A ^c   Blair, Willie C ^c  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b ST JOSEPH MERCY HOSPITAL   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

D DIMER; FIBRIN DEGRADATION PRODUCT; FIBRIN FRAGMENT D; INTERLEUKIN 10; PADGEM PROTEIN;

ARTICLE; BLOOD; CLINICAL PROTOCOL; COMPLICATION; COST EFFECTIVENESS ANALYSIS; EARLY DIAGNOSIS; ECHOGRAPHY; ETIOLOGY; EVALUATION; FEMALE; HIGH RISK POPULATION; HUMAN; HUMAN TISSUE; INCIDENCE; INJURY; INJURY SCALE; MAJOR CLINICAL STUDY; MALE; METABOLISM; METHODOLOGY; MIDDLE AGED; MULTIPLE TRAUMA; PRIORITY JOURNAL; PROPHYLAXIS; REPRODUCIBILITY; RISK ASSESSMENT; RISK BENEFIT ANALYSIS; RISK FACTOR; SCORING SYSTEM; SCREENING; THROMBOEMBOLISM; VEIN THROMBOSIS; VENOUS THROMBOEMBOLISM;

BLOOD; COMPLICATIONS; ETIOLOGY; FEMALE; FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; HUMANS; INTERLEUKIN-10; MALE; METABOLISM; METHODS; MIDDLE AGED; MULTIPLE TRAUMA; P-SELECTIN; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; RISK FACTORS; THROMBOEMBOLISM; ULTRASONOGRAPHY; VENOUS THROMBOSIS;

EID: 33646081068     PISSN: 00225282     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ta.0000197180.79965.bc     Document Type: Article

References (11)

1. Gearhart MM, Luchette FA, Proctor MC, et al. The risk assessment profile score identifies trauma patients at risk for deep vein thrombosis. Surgery. 2000;128:631-640.
2. Wakefield TW, Strieter RM, Downing LJ, et al. P-Selectin and TNF inhibition reduce venous thrombosis inflammation. J Surg Res. 1996;64:26-31.
3. Downing LJ, Wakefield TW, Strieter RM, et al. Anti-P-selectin antibody decreases inflammation and thrombus formation in venous thrombosis. J Vasc Surg. 1997;25:816-827, discussion, 828.
4. De Mitrio V, Marino R, Scaraggi FA, et al. Influence of factor VIII/von Willebrand complex on the activated protein C-resistance phenotype and on the risk for venous thromboembolism in heterozygous carriers of the factor V leiden mutation. Blood Coagul Fibrinolysis. 1999;10:409-416.
5. Henke PK, DeBrunye LA, Strieter RM, et al. Viral IL-10 gene transfer decreases inflammation and cell adhesion molecule expression in a rat model of venous thrombosis. J Immunol. 2000;164:2131-2141.
6. Owings JT, Gosselin RC, Anderson JT, Battistella FD, Bagley M, Larkin EC. Practical utility of the D-dimer assay for excluding thrombembolism in severely injured trauma patients. J Trauma. 2001;51:425-430.
7. Schmidt U, Enderson BL, Chen JP, Maull KI. D-dimer levels correlate with pathologic thrombosis in trauma patients. J Trauma. 1992;33:312-320.
8. Proctor M, Zajkowski P, Wahl W, Wakefield TW, Greenfield LJ. The role of P-selectin in venous thromboembolism associated with trauma. Presented at the 12th Annual Meeting of the American Venous Forum, February, 2000.
9. Perl M, Gebhard F, Knoferl MW, et al. The pattern of preformed cytokines in tissues frequently affected by blunt trauma. Shock. 2003;19:299-304.
10. Andre P, Hartwell D, Hrachovinova I, Saffaripour S, Wagner DD. Pro-coagulant state resulting from high levels of soluble p-selectin in blood. Proc Natl Acad Sci U S A. 2000;97:13835-13840.
11. Rectenwald J, Myers D, Hawley A, et al. D-dimer, P-selectin, and microparticles: novel markers to predict deep venous thrombosis. Presented at: 46th American Society of Hematology Meeting; December 5, 2004; San Diego, CA (poster).