Epidemiology of Vertebral Fractures: Implications for Vertebral Augmentation

Academic Radiology

Volumn 13, Issue 5, 2006, Pages 538-545

  Melton III, L Joseph ^a   Kallmes, David F ^a  

^a Mayo Clinic   (United States)

Author keywords

epidemiology; outcomes; Vertebral fracture; vertebroplasty

Indexed keywords

ARTICLE; BACKACHE; BONE TURNOVER; DAILY LIFE ACTIVITY; DISEASE SEVERITY; HUMAN; LONG TERM CARE; MORBIDITY; MORTALITY; OSTEOPOROSIS; OUTCOME ASSESSMENT; PATIENT REFERRAL; PERCUTANEOUS VERTEBROPLASTY; POSTMENOPAUSE; PRIORITY JOURNAL; QUALITY OF LIFE; RISK ASSESSMENT; RISK FACTOR; STATISTICAL SIGNIFICANCE; SYMPTOMATOLOGY; THORACOLUMBAR SPINE; VERTEBRA BODY; VERTEBRA FRACTURE; VERTEBRA MALFORMATION;

COMORBIDITY; INCIDENCE; LAMINECTOMY; LOW BACK PAIN; PROGNOSIS; RISK ASSESSMENT; RISK FACTORS; SPINAL FRACTURES; UNITED STATES;

EID: 33646069414     PISSN: 10766332     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.acra.2006.01.005     Document Type: Article

References (58)

1. Fink H.A., Milavetz D.L., Palermo L., et al., for the Fracture Intervention Trial Research Group. What proportion of incident radiographic vertebral deformities is clinically diagnosed and vice versa?. J Bone Miner Res 20 (2005) 1216-1222
2. Faciszewski T., and McKiernan F. Calling all vertebral fractures classification of vertebral compression fractures. a consensus for comparison of treatment and outcome. J Bone Miner Res 17 (2002) 185-191
3. Ross P.D. Clinical consequences of vertebral fractures. Am J Med 103 (1997) 30S-43S
4. Delmas P.D., van de Langerijt L., Watts N.T., et al. Underdiagnosis of vertebral fractures is a worldwide problem. the IMPACT Study. J Bone Miner Res 20 (2005) 557-563
5. National Osteoporosis Foundation Working Group on Vertebral Fractures. Assessing vertebral fractures. J Bone Miner Res 10 (1995) 518-523
6. Genant H.K., and Jergas M. Assessment of prevalent and incident vertebral fractures in osteoporosis research. Osteoporos Int 14 Suppl. 3 (2003) S43-S55
7. Genant H.K., Wu C.Y., van K.C., and Nevitt M.C. Vertebral fracture assessment using a semiquantitative technique. J Bone Miner Res 8 (1993) 1137-1148
8. Ferrar L., Jiang G., Adams J., and Eastell R. Identification of vertebral fractures. an update. Osteoporos Int 16 (2005) 717-728
9. Black D.M., Palermo L., Nevitt M.C., et al. Comparison of methods for defining prevalent vertebral deformities. the Study of Osteoporotic Fractures. J Bone Miner Res 10 (1995) 890-902
10. Jiang G., Eastell R., Barrington N.A., et al. Comparison of methods for the visual identification of prevalent vertebral fracture in osteoporosis. Osteoporos Int 15 (2004) 887-896
11. Leidig-Bruckner G., Limberg B., Felsenberg D., et al. Sex difference in the validity of vertebral deformities as an index of prevalent vertebral osteoporotic fractures. a population survey of older men and women. Osteoporos Int 11 (2000) 102-119
12. O'Neill T.W., Felsenberg D., Varlow J., et al. The prevalence of vertebral deformity in European men and women. the European Vertebral Osteoporosis Study. J Bone Miner Res 11 (1996) 1010-1018
13. Cooper C., Atkinson E.J., O'Fallon W.M., et al. Incidence of clinically diagnosed vertebral fractures. a population-based study in Rochester, Minnesota, 1985-1989. J Bone Miner Res 7 (1992) 221-227
14. Van der Klift M., De Laet C.E.D.H., McCloskey E.V., et al. The incidence of vertebral fractures in men and women. the Rotterdam Study. J Bone Miner Res 17 (2002) 1051-1056
15. Incidence of vertebral fracture in Europe. results from the European Prospective Osteoporosis Study (EPOS). J Bone Miner Res 17 (2002) 716-724
16. Winner S.J., Morgan C.A., and Evans J.G. Perimenopausal risk of falling and incidence of distal forearm fracture. BMJ 298 (1989) 1486-1488
17. The relationship between bone density and incident vertebral fracture in men and women. J Bone Miner Res 17 (2002) 2214-2221
18. Melton III L.J., and Cooper C. Magnitude and impact of osteoporosis and fractures. In: Marcus R., Feldman D., and Kelsey J. (Eds). Osteoporosis. ed 2. vol 1 (2001), Academic Press, San Diego 557-567
19. Ettinger B., Black D.M., Nevitt M.C., et al., The Study of Osteoporotic Fractures Research Group. Contribution of vertebral deformities to chronic back pain and disability. J Bone Miner Res 7 (1992) 449-456
20. Burger H., Van Daele P.L., Grashuis K., et al. Vertebral deformities and functional impairment in men and women. J Bone Miner Res 12 (1997) 152-157
21. Melton III L.J. Adverse outcomes of osteoporotic fractures in the general population. J Bone Miner Res 18 (2003) 1139-1141
22. Moro M., Hecker A.T., Bouxsein M.L., et al. Failure load of thoracic vertebrae correlates with lumbar bone mineral density measured by DXA. Calcif Tissue 56 (1995) 206-209
23. Marshall D., Johnell O., and Wedel H. Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. BMJ 312 (1996) 1254-1259
24. Crawford R.P., Cann C.E., and Keaveny T.M. Finite element models predict in vitro vertebral body compressive strength better than quantitative computed tomography. Bone 33 (2003) 744-750
25. Camp J.J., Karwoski R.A., Stacy M.C., et al. A system for the analysis of whole-bone strength from helical CT images. In: Amini A.A., and Manduca A. (Eds). Medical Imaging 2004. Physiology, Function, and Structure from Medical Images, Proceedings of SPIE (2004), Vol 5369 74-88
26. Homminga J., Van-Rietbergen B., Lochmüller E.M., et al. The osteoporotic vertebral structure is well adapted to the loads of daily life, but not to infrequent "error" loads. Bone 34 (2004) 510-516
27. Kirk D., and Fish S.A. Medical management of osteoporosis. Am J Managed Care 10 (2004) 445-455
28. Cummings S.R., Karpf D.B., Harris F., et al. Improvement in spine bone density and reduction in risk of vertebral fractures during treatment with antiresorptive drugs. Am J Med 112 (2002) 281-289
29. Riggs B.L., and Melton III L.J. Bone turnover matters. the raloxifene treatment paradox of dramatic decreases in vertebral fractures without commensurate increases in bone density. J Bone Miner Res 17 (2002) 11-14
30. Garnero P., Sornay-Rendu E., Claustrat B., et al. Biochemical markers of bone turnover, endogenous hormones and the risk of fractures in postmenopausal women. the OFELY Study. J Bone Miner Res 15 (2000) 1526-1536
31. Gerdhem P., Ivaska K.K., Alatalo S.L., et al. Biochemical markers of bone metabolism and prediction of fracture in elderly women. J Bone Miner Res 19 (2004) 386-393
32. Meier C., Nguyen T.V., Center J.R., et al. Bone resorption and osteoporotic fractures in elderly men. the Dubbo Osteoporosis Epidemiology Study. J Bone Miner Res 20 (2005) 579-587
33. Riggs B.L., Melton III L.J., and O'Fallon W.M. Drug therapy for vertebral fractures in osteoporosis. evidence that decreases in bone turnover and increases in bone mass both determine antifracture efficacy. Bone 18 Suppl. (1996) 197S-201S
34. Bouxsein M.L. Biomechanics of age-related fractures. In: Marcus R., Feldman D., and Kelsey J. (Eds). Osteoporosis. ed 2. vol 1 (2001), Academic Press, San Diego 509-531
35. Uppin A.A., Hirsch J.A., Centenera L.V., et al. Occurrence of new vertebral body fracture after percutaneous vertebroplasty in patients with osteoporosis. Radiology 226 (2003) 119-124
36. Kim S.H., Kang H.S., Choi J.-A., et al. Risk factors of new compression fractures in adjacent vertebrae after percutaneous vertebroplasty. Acta Radiol 45 (2004) 440-445
37. Myers E., and Wilson S.E. Biomechanics of osteoporosis and vertebral fracture. Spine 22 24S, Suppl (1997) 25S-31S
38. Klotzbuecher C.M., Ross P.D., Landsman P.B., et al. Patients with prior fractures have an increased risk of future fractures. a summary of the literature and statistical synthesis. J Bone Miner Res 15 (2000) 721-739
39. Black D.M., Cummings S.R., Karpf D.B., et al., for the Fracture Intervention Trial Research Group. Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Lancet 348 (1996) 1535-1541
40. Cummings S.R., Black D.M., Thompson D.E., et al. Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures. Results from the Fracture Intervention Trial. JAMA 280 (1998) 2077-2082
41. Ettinger B., Black D.M., Mitlak B.H., et al. Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene. results from a 3-year randomized clinical trial. JAMA 282 (1999) 637-645
42. Melton III L.J., Atkinson E.J., Cooper C., et al. Vertebral fractures predict subsequent fractures. Osteoporos Int 10 (1999) 214-221
43. Johnell O., Kanis J.A., Black D.M., et al. Associations between baseline risk factors and vertebral fracture risk in the Multiple Outcomes of Raloxifene Evaluation (MORE) Study. J Bone Miner Res 19 (2004) 764-772
44. Delmas P.D., Genant H.K., Crans G.G., et al. Severity of prevalent vertebral fractures and the risk of subsequent vertebral and nonvertebral fractures. results from the MORE trial. Bone 33 (2003) 522-532
45. Lunt M., O'Neill T.W., Felsenberg D., et al. Characteristics of a prevalent vertebral deformity predict subsequent vertebral fracture. results from the European Prospective Osteoporosis Study (EPOS). Bone 33 (2003) 505-513
46. Nevitt M.C., Ross P.D., Palermo L., et al., The Fracture Intervention Trial Research Group. Association of prevalent vertebral fractures, bone density, and alendronate treatment with incident vertebral fractures. effect of number and spinal location of fractures. Bone 25 (1999) 613-619
47. Berlemann U., Ferguson S.J., Nolte L.-P., et al. Adjacent vertebral failure after vertebroplasty. a biomechanical investigation. J Bone Joint Surg 84-B (2002) 748-752
48. Grados F., Depriester C., Cayrolle G., et al. Long-term observations of vertebral osteoporotic fractures treated by percutaneous vertebroplasty. Rheumatology 39 (2000) 1410-1414
49. Cummings S.R., and Melton III L.J. Epidemiology and outcomes of osteoporotic fractures. Lancet 359 (2002) 1761-1767
50. Chrischilles E.A., Butler C.D., Davis C.S., et al. A model of lifetime osteoporosis impact. Arch Intern Med 151 (1991) 2026-2032
51. Kanis J.A., Johnell O., Oden A., et al. The risk and burden of vertebral fractures in Sweden. Osteoporos Int 15 (2004) 20-26
52. Gold D.T., Lyles K.W., Shipp K.M., et al. Osteoporosis and its nonskeletal consequences. their impact on treatment decisions. In: Marcus R., Feldman D., and Kelsey J. (Eds). Osteoporosis. ed 2. vol 2 (2001), Academic Press, San Diego 479-484
53. Lips P., and van Schoor N.M. Quality of life in patients with osteoporosis. Osteoporos Int 16 (2005) 447-455
54. Melton III L.J. Excess mortality following vertebral fracture. J Am Geriatr Soc 48 (2000) 338-339
55. Kado D.M., Duong T., Stone K.L., et al. Incident vertebral fractures and mortality in older women. a prospective study. The Study of Osteoporotic Fractures Research Group. Osteoporos Int 14 (2003) 589-594
56. Johnell O. Economic implication of osteoporotic spine disease. cost to society. Eur Spine J 12 Suppl 2 (2003) S168-S169
57. Ray N.F., Chan J.K., Thamer M., et al. Medical expenditures for the treatment of osteoporotic fractures in the United States in 1995. report from the National Osteoporosis Foundation. J Bone Miner Res 12 (1997) 24-35
58. Greendale G.A., Barrett-Connor E., Ingles S., et al. Late physical and functional effects of osteoporotic fracture in women. the Rancho Bernardo Study. J Am Geriatr Soc 43 (1995) 955-961