Evaluation of the antihypertensive effect of Salvia scutellarioides in a model of hypertensive rats;Estudio del efecto antihipertensivo de la Salvia scutellarioides en un modelo de ratas hipertensas

Colombia Medica

Volumn 37, Issue 1, 2006, Pages 53-60

  Ramírez, Jorge ^a   Palacios, Mauricio ^a   Gutiérrez, Oscar ^a  

^a UNIVERSIDAD DEL VALLE   (Colombia)

Author keywords

Ethnopharmacology; Hypertension; L NAME; Mastranto; S. palaefolia; Salvia scutellarioides

Indexed keywords

ANTIHYPERTENSIVE AGENT; ENALAPRIL; N(G) NITROARGININE METHYL ESTER; PLANT EXTRACT; SALVIA SCUTELLARIOIDES EXTRACT; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; ETHNOPHARMACOLOGY; HISTOPATHOLOGY; HYPERTENSION; MALE; NON INVASIVE MEASUREMENT; NONHUMAN; RANDOMIZATION; RAT; SALVIA; SALVIA SCUTELLARIOIDES; SENSOR; STATISTICAL SIGNIFICANCE; TREATMENT OUTCOME;

EID: 33646058923     PISSN: 16579534     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Staessen JA, Wang J, Bianchi G, Birkenhager WH. Essential hypertension. Lancet 2003; 36: 1629-1641.
2. Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J. Global burden of hypertension: analysis of worldwide data. Lancet 2005; 365: 217-223.
3. López PJ, Jaramillo JP. Papel de la dimetilarginina asimétrica (ADMA), un inhibidor endógeno del óxido nítrico, en la génesis de las enfermedades cardiovasculares. Cardiología al Día 2000; 3: 14-18.
4. a. Bogotá, D.C.: Horizonte Impresores; 2001. p. 21-34.
5. Colmenares AJ, Ramírez AB. Salvia scutellarioides. En: Treinta plantas medicinales del Valle del Cauca. Fundamentos fitoquímicos y farmacológicos que sustentan sus usos.Cali:; 2001. p. 49-50.
6. Bernal HY, Correa JE. Salvia palaefolia. En: Especies vegetales promisorias en los paises del convenio Andrés Bello. Bogotá: SECAB; 1994. p. 1-156.
7. Ahmed AA, Castro B. Sesquiterpene lactones from Salvia palaefolia. Phytochemistry 1990; 29: 3581-3585.
8. Ohashi K, Bohgaki T, Shibuya H. Antihypertensive substance in the leaves of kumis kucing (Orthosiphon aristatus) in Java Island. Yakugaku Zasshi 2000; 120: 474-482.
9. Pechanova O, Dobesova Z, Cejka J, Kunes J, Zicha J. Vasoactive systems in L-NAME hypertension: the role of inducible nitric oxide synthase. J Hypertens 2004; 22: 167-173.
10. Sharapin N. Materias primas vegetales para la industria de productos fitoterapéuticos. In: Pinzón RS, (ed). Fundamentos de tecnología de productos fitoterapéuticos. Bogotá: CYTED; 2000. p. 17-26.
11. Widdop RE, Li XC. A simple versatile method for measuring tail cuff systolic blood pressure in conscious rats. Clin Sci (Lond) 1997; 93: 191-194.
12. Sventek P, Li JS, Grove K, Deschepper CF, Schiffrin EL. Vascular structure and expression of endothelin-1 gene in L-NAME-treated spontaneously hypertensive rats. Hypertension 1996; 27: 49-55.
13. Pechanova O, Bernatova I, Pelouch V, Babal P. L-NAME-induced protein remodeling and fibrosis in the rat heart. Physiol Res 1999; 48: 353-362.
14. Kung CF, Moreau P, Takase H, Luscher TF. L-NAME hypertension alters endothelial and smooth muscle function in rat aorta. Prevention by trandolapril and verapamil. Hypertension 1995; 26: 744-751.
15. Ono H, Ono Y, Frohlich ED. ACE inhibition prevents and reverses L-NAME-exacerbated nephrosclerosis in spontaneously hypertensive rats. Hypertension 1996; 27: 176-183.
16. Bernatova I, Pechanova O, Simko F. Effect of captopril in L-NAME-induced hypertension on the rat myocardium, aorta, brain and kidney. Exp Physiol 1999; 84: 1095-105.
17. Tribulova N, Okruhlicova L, Bernatova I, Pechanova O. Chronic disturbances in NO production results in histochemical and subcellular alterations of the rat heart. Physiol Res 2000; 49: 77-88.
18. Pinto YM, Paul M, Ganten D. Lessons from rat models of hypertension: from Goldblatt to genetic engineering. Cardiovasc Res 1998; 39: 77-88.
19. Pravenec M, Kren V. Genetic analysis of complex cardiovascular traits in the spontaneously hypertensive rat. Exp Physiol 2005; 90: 273-276.
20. Jover B, Mimran A. Nitric oxide inhibition and renal alterations. J Cardiovasc Pharmacol 2001; 38 (Suppl 2): 65-70.
21. Tharaux PL, Chatziantoniou C, Casellas D, Fouassier L, Ardaillou R, Dussaule JC. Vascular endothelin-1 gene expression and synthesis and effect on renal type I collagen synthesis and nephroangiosclerosis during nitric oxide synthase inhibition in rats. Circulation 1999 27; 99: 2185-2191.
22. Kadokami T, Egashira K, Kuwata K, Fukumoto Y, Kozai T, Yasutake H, et al. Altered serotonin receptor subtypes mediate coronary microvascular hyperreactivity in pigs with chronic inhibition of nitric oxide synthesis. Circulation 1996 15; 94: 182-189.
23. Henrion D, Dowell FJ, Levy BI, Michel JB. In vitro alteration of aortic vascular reactivity in hypertension induced by chronic NG-nitro-L-arginine methyl ester. Hypertension 1996; 28: 361-366.
24. Takemoto M, Egashira K, Usui M, Numaguchi K, Tomita 0H, Tsutsui H, et al. Important role of tissue angiotensin-converting enzyme activity in the pathogenesis of coronary vascular and myocardial structural changes induced by long-term blockade of nitric oxide synthesis in rats. J Clin Invest 1997; 99: 278-287.
25. Bernatova I, Pechanova O, Pelouch V, Simko F. Regression of chronic L-NAME-treatment-induced left ventricular hypertrophy: effect of captopril. J Mol Cell Cardiol 2000; 32: 177-185.
26. Takamitsu Y, Nakanishi T, Nishihara F, Hasuike Y, Izumi M, Inoue T, et al. A nitric oxide-generating beta-blocking agent prevents renal injury in the rat remnant kidney model. Comparative study of two beta-blocking drugs, nipradilol and propranolol. Nephron Physiol 2003; 93: 42-50.
27. De Oliveira CF, Nathan LP, Metze K, Moreno HJr., de L, I, Sucupira M, et al. Effect of Ca2+ channel blockers on arterial hypertension and heart ischaemic lesions induced by chronic blockade of nitric oxide in the rat. Eur J Pharmacol 1999 4; 373: 195-200.
28. Ono Y, Ono H, Frohlich ED. Hydrochlorothiazide exacerbates nitric oxide-blockade nephrosclerosis with glomerular hypertension in spontaneously hypertensive rats. J Hypertens 1996; 14: 823-828.