Neuropathy, axonal Na+/K+ pump function and activity-dependent excitability changes in end-stage kidney disease

Clinical Neurophysiology

Volumn 117, Issue 5, 2006, Pages 992-999

  Krishnan, Arun V ^a,b   Phoon, Richard K S ^a   Pussell, Bruce A ^a   Charlesworth, John A ^a   Bostock, Hugh ^c   Kiernan, Matthew C ^a,b  

^a PRINCE OF WALES HOSPITAL   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Membrane potential; Na+ K+ pump; Nerve excitability; Potassium; Uraemic neuropathy

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); BETA 2 MICROGLOBULIN; NEUROTOXIN; PARATHYROID HORMONE; POTASSIUM; UREA;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONCENTRATION (PARAMETERS); DEPOLARIZATION; DIALYSIS; FEMALE; HAND MUSCLE; HEMODIALYSIS; HUMAN; HYPERKALEMIA; HYPERPOLARIZATION; KIDNEY FAILURE; MALE; MUSCLE CONTRACTION; NERVE EXCITABILITY; NEUROPATHY; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STRENGTH;

EID: 33646029744     PISSN: 13882457     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinph.2006.02.002     Document Type: Article

References (41)

1. Angus-Leppan H., and Burke D. The function of large and small nerve fibers in renal failure. Muscle Nerve 15 (1992) 288-294
2. Babb A.L., Popovich R.P., Christopher T.G., and Scribner B.H. The genesis of the square meter-hour hypothesis. Trans Am Soc Artif Intern Organs 17 (1971) 81-91
3. Battaglia F., Quartarone A., Bagnato S., Rizzo V., Morgante F., Floccari F., Romeo A., Sant'Angelo A., Grasso G., Girlanda P., and Buemi M. Brain dysfunction in uremia: a question of cortical hyperexcitability?. Clin Neurophysiol 116 (2005) 1507-1514
4. Bergmans J. The physiology of single human nerve fibres (1970), University of Louvain, Vander, Belgium
5. Bergstrom J., and Hultman E. Water, electrolyte and glycogen content of muscle tissue in patients undergoing regular dialysis therapy. Clin Nephrol 2 (1974) 24-34
6. Bostock H., and Bergmans J. Post-tetanic excitability changes and ectopic discharges in a human motor axon. Brain 117 (1994) 913-928
7. Bostock H., and Grafe P. Activity-dependent excitability changes in normal and demyelinated rat spinal root axons. J Physiol (Lond) 365 (1985) 239-257
8. Bostock H., Burke D., and Hales J.P. Differences in behaviour of sensory and motor axons following release of ischaemia. Brain 117 (1994) 225-234
9. Bostock H., Cikurel K., and Burke D. Threshold tracking techniques in the study of human peripheral nerve. Muscle Nerve 21 (1998) 137-158
10. Bostock H., Walters R.J., Andersen K.V., Murray N.M., Taube D., and Kiernan M.C. Has potassium been prematurely discarded as a contributing factor to the development of uraemic neuropathy?. Nephrol Dial Transplant 19 (2004) 1054-1057
11. Bostock H., Lin C.S.-Y., Howells J., Trevillion L., Jankelowitz S., and Burke D. After-effects of near-threshold stimulation in single human motor axons. J Physiol (Lond) 564 (2005) 931-940
12. Cotton J.R., Woodard T., Carter N.W., and Knochel J.P. Resting skeletal muscle membrane potential as an index of uremic toxicity. A proposed new method to assess adequacy of hemodialysis. J Clin Invest 63 (1979) 501-506
13. David G., Modney B., Scappaticci K.A., Barrett J.N., and Barrett E.F. Electrical and morphological factors influencing the depolarizing after-potential in rat and lizard myelinated axons. J Physiol (Lond) 489 (1995) 141-157
14. Greene D.A. A sodium-pump defect in diabetic peripheral nerve corrected by sorbinil administration: relationship to myo-inositol metabolism and nerve conduction slowing. Metabolism 35 (1986) 60-65
15. Halperin M.L., and Kamel K.S. Potassium. Lancet 352 (1998) 135-140
16. Hodgkin A.L., and Keynes R.D. Movement of cations during recovery in nerve. Symp Soc Exp Biol 8 (1954) 423-437
17. Hodgkin A.L., and Keynes R.D. Active transport of cations in giant axons from Sepia and Loligo. J Physiol (Lond) 128 (1955) 28-60
18. Kaji R. Physiology of conduction block in multifocal motor neuropathy and other demyelinating neuropathies. Muscle Nerve 27 (2003) 285-296
19. Kaji R., and Sumner A.J. Ouabain reverses conduction disturbances in single demyelinated nerve fibers. Neurology 39 (1989) 1364-1368
20. Kiernan M.C., and Bostock H. Effects of membrane polarization and ischaemia on the excitability properties of human motor axons. Brain 123 (2000) 2542-2551
21. Kiernan M.C., Burke D., Andersen K.V., and Bostock H. Multiple measures of axonal excitability: a new approach in clinical testing. Muscle Nerve 23 (2000) 399-409
22. Kiernan M.C., Cikurel K., and Bostock H. Effects of temperature on the excitability properties of human motor axons. Brain 124 (2001) 816-825
23. Kiernan M.C., Guglielmi J.M., Kaji R., Murray N.M., and Bostock H. Evidence for axonal membrane hyperpolarisation in multifocal motor neuropathy with conduction block. Brain 125 (2002) 664-675
24. Kiernan M.C., Walters R.J., Andersen K.V., Taube D., Murray N.M., and Bostock H. Nerve excitability changes in chronic renal failure indicate membrane depolarization due to hyperkalaemia. Brain 125 (2002) 1366-1378
25. Kiernan M.C., Lin C.S., and Burke D. Differences in activity-dependent hyperpolarisation in human sensory and motor axons. J Physiol (Lond) 558 (2004) 341-349
26. Kitano Y., Kuwabara S., Misawa S., Ogawara K., Kanai K., Kikkawa Y., Yagui K., and Hattori T. The acute effects of glycemic control on axonal excitability in human diabetics. Ann Neurol 56 (2004) 462-467
27. Krishnan A.V., and Kiernan M.C. Altered nerve excitability properties in established diabetic neuropathy. Brain 128 (2005) 1178-1187
28. Krishnan A.V., Phoon R.K., Pussell B.A., Charlesworth J.A., Bostock H., and Kiernan M.C. Altered motor nerve excitability in end-stage kidney disease. Brain 128 (2005) 2164-2174
29. Kuwabara S., Ogawara K., Harrori T., Suzuki Y., and Hashimoto N. The acute effects of glycemic control on axonal excitability in human diabetic nerves. Intern Med 41 (2002) 360-365
30. Kuwabara S., Ogawara K., Sung J.Y., Mori M., Kanai K., Hattori T., Yuki N., Lin C.S., Burke D., and Bostock H. Differences in membrane properties of axonal and demyelinating Guillain-Barre syndromes. Ann Neurol 52 (2002) 180-187
31. Lowitzsch K., Gohring U., Hecking E., and Kohler H. Refractory period, sensory conduction velocity and visual evoked potentials before and after haemodialysis. J Neurol Neurosurg Psychiatry 44 (1981) 121-128
32. McIntyre C.C., Richardson A.G., and Grill W.M. Modeling the excitability of mammalian nerve fibers: influence of afterpotentials on the recovery cycle. J Neurophysiol 87 (2002) 995-1006
33. Morita K., David G., Barrett J.N., and Barrett E.F. Posttetanic hyperpolarisation produced by electrogenic Na(+)-K+ pump in lizard axons impaled near their motor terminals. J Neurophysiol 70 (1993) 1874-1884
34. Nakajima S., and Takahashi K. Post-tetanic hyperpolarisation and electrogenic Na pump in stretch receptor neurone of crayfish. J Physiol (Lond) 187 (1966) 105-127
35. Nielsen V.K. The peripheral nerve function in chronic renal failure. V. Sensory and motor conduction velocity. Acta Med Scand 194 (1973) 445-454
36. Rakowski R.F., Gadsby D.C., and De Weer P. Stoichiometry and voltage dependence of the sodium pump in voltage-clamped, internally dialyzed squid giant axon. J Gen Physiol 93 (1989) 903-941
37. Rang H.P., and Ritchie J.M. On the electrogenic sodium pump in mammalian non-myelinated nerve fibres and its activation by various external cations. J Physiol (Lond) 196 (1968) 183-221
38. Ritchie J., and Straub R. The hyperpolarisation which follows activity in mammalian non-medullated fibres. J Physiol (Lond) 136 (1957) 80-97
39. Vagg R., Mogyoros I., Kiernan M.C., and Burke D. Activity-dependent hyperpolarisation of human motor axons produced by natural activity. J Physiol (Lond) 507 (1998) 919-925
40. Van den Neucker K., Vanderstraeten G., and Vanholder R. Peripheral motor and sensory nerve conduction studies in haemodialysis patients. A study of 54 patients. Electromyogr Clin Neurophysiol 38 (1998) 467-474
41. Vanholder R., De Smet R., Hsu C., Vogeleere P., and Ringoir S. Uremic toxicity: the middle molecule hypothesis revisited. Semin Nephrol 14 (1994) 205-218