Penicillin-resistant pneumococci in Sweden 1997-2003: Increased multiresistance despite stable prevalence and decreased antibiotic use

Microbial Drug Resistance

Volumn 12, Issue 1, 2006, Pages 16-22

  Högberg, Liselotte ^a,b   Ekdahl, Karl ^a,b   Sjöström, Karin ^a,b   Olsson Liljequist, Barbro ^a   Walder, Mats ^c   Melander, Eva ^c   Ringberg, Håkan ^d   Normark, Birgitta Henriques ^a,b  

^a SWEDISH INSTITUTE FOR INFECTIOUS DISEASE CONTROL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c LUND UNIVERSITY HOSPITAL   (Sweden)

^d Regional Centre of Communicable Disease Control   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BETA LACTAM ANTIBIOTIC; COTRIMOXAZOLE; ERYTHROMYCIN; PENICILLIN G; SULFAMETHOXAZOLE; TETRACYCLINE; TRIMETHOPRIM;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIUM ISOLATE; BLOOD GROUP TYPING; DRUG USE; HUMAN; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; PENICILLIN RESISTANCE; PREVALENCE; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIAE; SWEDEN;

ADOLESCENT; ADULT; AGED; ANTI-BACTERIAL AGENTS; CHILD; CHILD, PRESCHOOL; DRUG RESISTANCE, MULTIPLE, BACTERIAL; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; MALE; MIDDLE AGED; PENICILLIN RESISTANCE; STREPTOCOCCUS PNEUMONIAE; SWEDEN; TIME FACTORS;

BACTERIA (MICROORGANISMS); STREPTOCOCCUS PNEUMONIAE;

EID: 33646028165     PISSN: 10766294     EISSN: None     Source Type: Journal    
DOI: 10.1089/mdr.2006.12.16     Document Type: Article

References (33)

1. Appelbaum, P.C. 1992. Antimicrobial resistance in Streptococcus pneumoniae: an overview. Clin. Infect. Dis. 15:77-83.
2. Arason, V.A., A. Gunnlaugsson, J.A. Sigurdsson, H. Erlendsdottir, S. Gudmundsson, and K.G. Kristinsson. 2002. Clonal spread of resistant pneumococci despite diminished antimicrobial use, Microb. Drug Resist. 8:187-192.
3. Baquero, F. 1996. Epidemiology and management of penicillin resistant pneumococci. Curr. Opin. Infect. Dis. 9:372-377.
4. Boccia, D., S.S. Alegiani, A. Pantosti, M.L. Moro, and G. Traversa. 2004. The geographic relationship between the use of antimicrobial drugs and the pattern of resistance for Streptococcus pneumoniae in Italy. Eur. J. Clin. Pharmacol. 60:115-119.
5. Bronzwaer, S.L., O. Cars, U. Buchholz, S. Mölstad, W. Goettsch, I.K. Veldhuijzen, J.L. Kool, M.J. Sprenger, and J.E. Degener. 2002. A European study on relationship between antimicrobial use and antimicrobial resistance. Emerg. Infect. Dis. 8:278-282.
6. Cars, O., and K. Ekdahl (eds). 2004. SWEDRES 2003-A report on Swedish antibiotic utilisation and resistance in human medicine. STRAMA and Swedish Institute for Infectious Disease Control. (Available at http://www. smittskyddsinstitutet.se/upload/Publikationer/Swedres-2003.pdf)
7. Cars, O., and A. Melander. 2001. Variation in antibiotic use in the European Union. Lancet 357:1851-1853.
8. Ekdahl, K., and O. Cars. 1999. Role of communicable disease control measures in controlling the spread of resistant pneumococci: the Swedish model. Clin. Microbiol. Infect. 5(Suppl 4):S48-S54.
9. Ekdahl, K., and C. Kamme. 1994. Increasing resistance to penicillin in Streptococcus pneumoniae in southern Sweden. Scand. J. Infect. Dis. 26:301-305.
10. Forsgren, A., and M. Walder. 1994. Antimicrobial susceptibility of bacterial isolates in south Sweden including a 13-year follow up study on some respiratory tract pathogens. APMIS 102:227-235.
11. Garcia-Rey, C., L. Aguilar, F. Baquero, J. Casal, and R. Dal-Ré. 2002. Importance of local variations in antibiotic consumption and geographical differences of erytromycin and penicillin resistance in Streptococcus pneumoniae. J. Clin. Microbiol. 40:159-164.
12. Granizo, J.J., L. Aguilar, J. Casal, C. Garcia-Rey, R. Dal-Re, and F. Baquero. 2000. Streptococcus pneumoniae resistance to erythromycin and penicillin in relation to macrolide and β-lactam consumption in Spain 1979-1997. J. Antimicrob. Chemother. 46:767-773.
13. Halbert S.P., L. Swick, and C. Sonn. 1955. The use of precipitin analysis in agar for the study of human streptococcal infections. II. Ouchterlony and Oakley techniques. J. Exp. Med. 101:557-576.
14. Henrichsen, J. 1995. Six newly recognized types of Streptococcus pneumoniae. J. Clin. Microbiol. 33:2759-2762.
15. Högberg, L., B. Henriques Normark, H. Ringberg, K. Stenqvist, H. Fredlund, P. Geli P, K. Grabowska, E. Melander, M. Laurell, C. Åhrén, E. Törnqvist, R. Fält, G. Möllerberg, and K. Ekdahl. 2004. The impact of active intervention on the spread of penicillin-resistant Streptococcus pneumoniae in Swedish day-care centres. Scand. J. Infect. Dis. 36:629-635.
16. Jacobs, M.R., S. Bajaksouzian, P.C. Appelbaum, and A. Bolstrom. 1992. Evaluation of the E-Test for susceptibility testing of pneumococci. Diagn. Microbiol. Infect. Dis. 15:473-478.
17. Jacobs, M.R, D. Felmingham, P.C. Appelbaum, R.N. Gruneberg, and the Alexander Project Group. 2003. The Alexander Project 1998-2000: susceptibility of pathogens isolated from community-acquired respiratory tract infection to commonly used antimicrobial agents. J. Antimicrob. Chemother. 52:229-246.
18. Jansson A., M. Arneborn, and K. Ekdahl. 2005. Sensitivity of the Swedish statutory surveillance for communicable diseases 1998-2002, assessed by the capture-recapture method. Epidemiol. Infect. 133:401-407.
19. Joloba, M.L., A. Windau, S. Bajaksouzian, P.C. Appelbaum, W.P. Hausdorff, and M.R. Jacobs. 2001. Pneumococcal conjugate vaccine serogroups of Streptococcus pneumoniae isolates and the antimicrobial susceptibility of such isolates in children with otitis media. Clin. Infect. Dis. 33:1489-1494.
20. Lund, E., and J. Henrichsen. 1978. Laboratory diagnosis, serology and epidemiology of Streptococcus pneumoniae, In T. Bergan, and J.R. Norris (eds.), Methods in microbiology, vol 12. Academic Press, New York, pp. 241-262.
21. McGee, L., K. Kristinsson, and A. Tomasz. 2001. Serogroups and clones of antibiotic resistant pneumococci. In A. Tomasz, (ed). Streptococcus pneumoniae. Molecular biology and mechanisms of disease. Mary Ann Liebert Inc., New York, pp. 375-379.
22. Melander, E., K. Ekdahl, G. Jönsson, and S. Mölstad. 2000. Frequency of penicillin-resistant pneumococci in children is correlated to community utilization of antibiotics. Pediatr. Infect. Dis. J. 19:1172-1177.
23. Melander, E., H.B. Hansson, S. Mölstad, K. Persson, and H. Ringberg. 2004. Limited spread of penicillin-nonsusceptible pneumococci, Skåne County, Sweden. Emerg. Infect. Dis. 10:1082-1087.
24. Mölstad, S., and O. Cars. 1999. Major changes in the use of antibiotics following a national programme: Swedish Strategic Programme for the Rational Use of Agents and Surveillance of resistance (STRAMA). Scand. J. Infect. Dis. 31:191-195.
25. Mölstad, S., C.S. Lundborg, A.K. Karlsson, and O. Cars. 2002. Antibiotic prescription rates vary markedly between 13 European countries. Scand. J. Infect. Dis. 34:366-371.
26. Neeling, A.J., B.P. Overbeek, A.M. Horrevorts, E.E.J. Ligtvoet, and W.G. Goerrsch. 2001. Antibiotic use and resistance of Streptococcus pneumoniae in the Netherlands during the period 1994-1999. J. Antimicrob. Chemother. 48:441-444.
27. Olsson-Liljequist, B., P. Larsson, M. Walder, and H. Miörner. 1997. Antimicrobial susceptibility testing in Sweden. III. Methods for susceptibility testing. Scand. J. Infect. Dis. Suppl. 105:13-23.
28. Olsson-Liljequist, B., L. Burman, and I. Kallings. 1992. Antibiotic susceptibility of upper respiratory tract pathogens in Sweden: a seven year follow up including loracarbef. Swedish Respiratory Tract Study Group. Scand. J. Infect. Dis. 24:485-493.
29. Swedish Reference Group for Antibiotics and its subcommittee on methodology (SRGA-M). The principles behind SRGA breakpoints.[online] (Accessed at http://www.srga.org/ on 5 August 2005.)
30. Skulnick, M., G.W. Small, P. Lo, M.P. Patel, C.R. Porter, D.E. Low, S. Matsumura, and T. Mazzulli. 1995. Evaluation of accuracy and reproducibility of E test for susceptibility testing of Streptococcus pneumoniae to penicillin, cefotaxime and ceftriaxone. J. Clin. Microbiol. 33:2334-2337.
31. Statistics Sweden. Statistical database. (Accessed at http://www. scb.se on 8 August 2005.)
32. Tomasz, A. 1997. Antibiotic resistance in Streptococcus pneumoniae: an overview. Clin. Infect. Dis. 24(Suppl 1):S85-S88.
33. WHO Collaborating Centre for Drug Statistics. 2002. Guidelines for ATC classification and DDD assignment. WHO Collaborating Centre for Drug Statistics. Oslo, Norway.