Retroviral vector mediated vascular endothelial growth factor gene therapy for experimental rabbits with cerebral ischemia

Chinese Journal of Clinical Rehabilitation

Volumn 10, Issue 12, 2006, Pages 59-61

  Zeng, Xian Wei ^a   Shen, Jian Kang ^a   Sun, Qing Fang ^a   Bian, Liu Guan ^a   Zhao, Wei Guo ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; MESSENGER RNA; RETROVIRUS VECTOR; VASCULOTROPIN;

AGAR GEL ELECTROPHORESIS; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ISCHEMIA; CAPILLARY DENSITY; CELL CULTURE; CONTROLLED STUDY; DRUG EFFICACY; EXPRESSION VECTOR; FEASIBILITY STUDY; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RANDOMIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT OUTCOME; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING;

EID: 33646024946     PISSN: 16715926     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Hai J, Li ST, Lin Q, et al.Vascular endothelial growth factor expression and angiogenesis induced by chronic cerebral hypoperfusion in rat brain. Neurosurgery 2003;53(4):963-70;
2. Hayashi T, Noshita N, Sugawara T,et al. Temporal profile of angiogenesis and expression of related genes in the brain after ischemia. J Cereb Blood Flow Metab 2003;23(2):166-80
3. Chinese source. 1997,19(5):236-23
4. Tsurumi Y, Takeshita S, Chen D, et al. Direct intramuscular gene transfer of naked DNA encoding vascular endothelial growth factor augments collateral development and tissue perfusion. Circulation 1996;94(12):3281-90
5. Schumacher B, Pecher P, von Specht BU. et al. Induction of neoangiogenesis in ischemic myocardium by human growth factors: first clinical results of a new treatment of coronary heart disease.Circulation 1998;97(7):645-50
6. Mack CA, Patel SR,Schwarz EA,et al.Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart.J Thorac Cardiovasc Surg 1998;115(1): 168-76
7. Hakim AM.Ischemic penumbra-the therapeutic window. Neurology 1998;51(3): 44-46
8. Morishita R. Adventure of gene therapy into the brain: A new era for cardiovascular gene therapy.Circ Res 2000;87(9):719-21
9. Carmeliet P, Cullen D. Molecular basis of angiogenesis. Role of VEGF and VE-cadherin.Ann N Y Acad Sci 2000;902:249-62
10. Mack CA, Magovern CJ, Budenbender KT, et al. Salvage angiogenesis induced by adenovirus-mediated gene transfer of vascular endothelial growth factor protects against ischemic vascular occlusion.J Vasc Surg 1998;27(4):699-709