Rap2, but not Rap1 GTPase is expressed in human red blood cells and is involved in vesiculation

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1763, Issue 3, 2006, Pages 330-335

  Greco, Fabio ^a   Ciana, Annarita ^a   Pietra, Daniela ^a   Balduini, Cesare ^a   Minetti, Giampaolo ^a   Torti, Mauro ^a  

^a UNIVERSITY OF PAVIA   (Italy)

Author keywords

Rap1; Rap2; Red blood cells; Small GTPases; Vesiculation

Indexed keywords

CALCIUM ION; GUANOSINE TRIPHOSPHATASE; IONOPHORE; PROTEIN SUBUNIT; RAP PROTEIN; RAP1 PROTEIN;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LEUKOCYTE; MEMBRANE VESICLE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RETICULOCYTE; RNA EXTRACTION; THROMBOCYTE;

ERYTHROCYTES; HUMANS; RAP GTP-BINDING PROTEINS; RAP1 GTP-BINDING PROTEINS; RNA, MESSENGER; TRANSPORT VESICLES;

EID: 33646023384     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2006.02.001     Document Type: Article

References (25)

1. Torti M., and Lapetina E.G. Structure and function of Rap proteins in human platelets. Thromb. Haemost. 71 (1994) 533-543
2. Paganini S., Guidetti G.F., Catricalà S., Trionfini P., Panelli S., Balduini C., and Torti M. Biochimie (2005 (Sep. 21)) (electronic publication ahead of print)
3. Bos J.L., de Rooij J., and Reedquist K.A. Rap1 signalling: adhering to new models. Nat. Rev., Cell Biol. 2 (2001) 369-377
4. Caron E. Cellular functions of the Rap1 GTP-binding protein: a pattern emerges. J. Cell Sci. 116 (2003) 435-440
5. Bos J.L., de Bruyn K., Enserink J., Kuiperij B., Rangarajan S., Rehmann H., Riedl J., de Rooij J., van Mansfeld F., and Zwartkruis F. The role of Rap1 in integrin-mediated cell adhesion. Biochem. Soc. Trans. 31 (2003) 83-86
6. Pizon V., Desjardins M., Bucci C., Parton R.G., and Zerial M. Association of Rap1a and Rap1b proteins with late endocytic/phagocytic compartments and Rap2a with the Golgi complex. J. Cell Sci. 107 (1994) 1661-1670
7. Maridonneau-Parini I., and de Gunzburg J. Association of rap1 and rap2 proteins with the specific granules of human neuthophils. Translocation to the plasma membrane during cell activation. J. Biol. Chem. 267 (1992) 6396-6402
8. De Flora A., Damonte G., Sdraffa A., Franco L., and Benatti U. Heterogeneity of guanine nucleotide binding proteins in human red blood cell membranes. Adv. Exp. Med. Biol. 307 (1991) 161-171
9. Boukharov A.A., and Cohen C.M. Guanine nucleotide-dependent translocation of RhoA from cytosol to high affinity membrane binding sites in human erythrocytes. Biochem. J. 330 (1998) 1391-1398
10. Vidal M.J., and Stahl P.D. The small GTP-binding proteins Rab4 and ARF are associated with released exosomes during reticulocyte maturation. Eur. J. Cell Biol. 60 (1993) 261-267
11. Wang K.L., Khan M.T., and Roufogalis B.D. Identification and characterization of a calmodulin-binding domain in Ral-A, a Ras-related GTP-binding protein purified from human erythrocyte membrane. J. Biol. Chem. 272 (1997) 16002-16009
12. Low T.Y., Seow T.K., and Chung M.C. Separation of human erythrocyte membrane associated proteins with one-dimensional and two-dimensional gel electrophoresis followed by identification with matrix-assisted laser desorption/ionization-time of flight mass spectrometry. Proteomics 2 (2002) 1229-1239
13. Kakhniashvili D.G., Bulla Jr. L.A., and Goodman S.R. The human erythrocyte proteome: analysis by ion trap mass spectrometry. Mol. Cell. Proteomics 3 (2004) 501-509
14. Murphy M.M., Zayed M.A., Evans A., Parker C.E., Ataga K.I., Telen M.J., and Parise L.V. Role of Rap1 in promoting sickle red blood cell adhesion to laminin via BCAM/LU. Blood 105 (2005) 3322-3329
15. Stengelin M.K., and Hoffman J.F. Na,K-ATPase subunit isoforms in human reticulocytes: evidence from reverse transcription-PCR for the presence of α1, α3, β2, β3, and γ. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 5943-5948
16. Hoffman J.F., Wickrema A., Potapova O., Milanick M., and Yingst D.R. Na pump isoforms in human erythroid progenitor cells and mature erythrocytes. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 14572-14577
17. Beutler E., West C., and Blume K.G. The removal of leukocytes and platelets from whole blood. J. Lab. Clin. Med. 88 (1976) 328-333
18. Minetti G., Ciana A., and Balduini C. Differential sorting of tyrosine kinases and phosphotyrosine phosphatases acting on band 3 during vesiculation of human erythrocytes. Biochem. J. 377 (2004) 489-497
19. Lova P., Campus F., Lombardi R., Cattaneo M., Sinigaglia F., Balduini C., and Torti M. Contribution of protease-activated receptors 1 and 4 and glycoprotein Ib-IX-V in the Gi-independent activation of platelet Rap1B by thrombin. J. Biol. Chem. 279 (2004) 25299-25306
20. Dodge J.T., Mitchell C., and Hanahan D.J. The preparation and chemical characteristics of hemoglobin-free ghosts of human erythrocytes. Arch. Biochem. Biophys. 100 (1963) 119-130
21. Greco F., Sinigaglia F., Balduini C., and Torti M. Activation of the small GTPase Rap2B in agonist-stimulated human platelets. J. Thromb. Haemost. 2 (2004) 2223-2230
22. Nagel R.L., and Platt O.S. General pathophysiology of sickle cell anemia. In: Steinberg M.H., Forget B.G., Higgs D.R., et al. (Eds). Disorders of Haemoglobin (2001), Cambridge Univ. Press, Cambridge UK 494-527
23. Wagner G.M., Chiu D.T., Yee M.C., and Lubin B.H. Red cell vesiculation - A common membrane physiologic event. J. Lab. Clin. Med. 108 (1986) 315-324
24. Westerman M.P., Cole E.R., and Wu K. The effect of spicules obtained from sickle red cells on clotting activity. Br. J. Haematol. 56 (1984) 557-562
25. 2+). Nature 261 (1976) 58-60