Apheresis instrument settings influence infused absolute lymphocyte count affecting survival following autologous peripheral hematopoietic stem cell transplantation in non-Hodgkin's lymphoma: The need to optimize instrument setting and define a lymphocyte collection target

Bone Marrow Transplantation

Volumn 37, Issue 9, 2006, Pages 811-817

  Katipamula, R ^a   Porrata, Luis F ^b   Gastineau, D A ^a,b   Markovic, S N ^b   Moore, S B ^a   Greiner, C ^a   Burgstaler, E A ^a   Padley, D J ^a   Winters, J L ^a  

^a MAYO CLINIC   (United States)

^b Mayo Clinic   (United States)

Author keywords

Apheresis instruments; Autograft absolute lymphocyte count; Autologous peripheral blood hematopoietic stem cell transplantation; Non Hodgkin's lymphoma; Survival

Indexed keywords

CARMUSTINE; CYCLOPHOSPHAMIDE; CYTARABINE; ETOPOSIDE; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MELPHALAN;

ADULT; AGED; APHERESIS; ARTICLE; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; AUTOLOGOUS PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; BIOMEDICAL TECHNOLOGY ASSESSMENT; CANCER SURVIVAL; CLINICAL PROTOCOL; CONTROLLED STUDY; FEMALE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MEDICAL INSTRUMENTATION; MULTIVARIATE ANALYSIS; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL; PROGNOSIS; TREATMENT OUTCOME; WHOLE BODY RADIATION;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BLOOD COMPONENT REMOVAL; FEMALE; HUMANS; LYMPHOCYTE COUNT; LYMPHOMA, NON-HODGKIN; MALE; MIDDLE AGED; PROGNOSIS; RETROSPECTIVE STUDIES; STEM CELL TRANSPLANTATION; SURVIVAL ANALYSIS; SURVIVORS; TIME FACTORS; TRANSPLANTATION, AUTOLOGOUS;

EID: 33646020400     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/sj.bmt.1705338     Document Type: Article

References (17)

1. Porrata LF, Litzow MR, Tefferi A, Letendre L, Kumar S, Geyer SM et al. Early lymphocyte recovery is predictive factor for prolonged survival after autologous hematopoietic stem cell transplantation for acute myelogenous leukemia. Leukemia 2002; 16: 1311-1318.
2. Porrata LF, Ingle JN, Litzow MR, Geyer S, Markovic SN. Prolonged survival associated with early lymphocyte recovery after autologous hematopoietic stem cell transplantation for patients with metastatic breast cancer. Bone Marrow Transplant 2001; 28: 865-871.
3. Nieto Y, Shpall EJ, Mcniece IK, Nawz S, Beaudet J, Rosinski S et al. Prognostic analysis of the early lymphocyte recovery in patients with advanced breast cancer receiving high-dose chemotherapy with an autologous hematopoietic progenitor cell transplant. Clin Cancer Res 2004; 10: 5076-5086.
4. Porrata LF, Inwards DJ, Micallef IN, Ansell SM, Geyer SM, Markovic SN. Early lymphocyte recovery post autologous haematopoietic stem cell transplantation is associated with better survival in Hodgkin's lymphoma. Br J Haematol 2002; 117: 629-633.
5. Gordan LN, Sugrue MW, Lynch JW, Williams KD, Khan SA, Mored JS. Correlation of early lymphocyte recovery and progression-free survival after autologous stem-cell transplant in patients with Hodgkin's and non-Hodgkin's lymphoma. Bone Marrow Transplant 2003; 31: 1009-1013.
6. Kim H, Sohn HJ, Kim SE, Kang HJ, Park S, Kim S et al. Lymphocyte recovery as a positive predictor of prolonged survival after autologous peripheral blood stem cell transplantation in T-cell non-Hodgkin's lymphoma. Bone Marrow Transplant 2004; 34: 43-49.
7. Porrata LF, Gertz MA, Inwards DJ, Litzow MR, Lacy MQ, Tefferi A et al. Early lymphocyte recovery predicts superior survival after autologous hematopoietic stem cell transplantation in multiple myeloma or non-Hodgkin's lymphoma. Blood 2001; 98: 579-585.
8. Porrata LF, Gertz MA, Litzow MR, Lacy MQ, Dispenzieri A, Inwards DJ et al. Early lymphocyte recovery predicts superior survival after autologous hematopoietic stem cell transplantation for patients with primary systemic amyloidosis. Clin Cancer Res 2005; 11: 1210-1218.
9. Porrata LF, Gertz MA, Geyer SM, Litzow MR, Gastineau DA, Moore SB et al. The dose of infused lymphocytes in the autograft directly correlates with clinical outcomes after autologous peripheral blood hematopoietic stem cell transplantation in multiple myeloma. Leukemia 2004; 18: 1085-1092.
10. Porrata LF, Litzow MR, Inwards DJ, Gastineau DA, Moore SB, Pineda AA et al. Infused peripheral blood autograft absolute lymphocyte count correlates with day 15 absolute lymphocyte count and clinical outcome after autologous peripheral hematopoietic stem cell transplantation in non-Hodgkin's lymphoma. Bone Marrow Transplant 2004; 33: 291-298.
11. Burgstaler EA, Pineda AA, Winters JL. Hematopoietic progenitor cell large volume leukapheresis (LVL) on the Fenwal amicus blood separator. J Clin Apheresis 2004; 19: 103-111.
12. Cheson BD, Horning SJ, Coiffier B, Shipp MA, Fisher RI, Connors JM et al. Report of an international workshop to standardize response criteria for non-Hodgkin's lymphomas. J Clin Oncol 1999; 17: 1244-1253.
13. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958; 53: 457-481.
14. Cox DR. Regression models and life tables. J R Stat Soc B 1972; 34: 187-202.
15. Snyder EL, Baril L, Cooper DL, Min K, Mechanic S, Stoddart L et al. In vitro collection and post transfusion engraftment characteristics of MNCs obtained by using a new separator for autologous PBPC transplantation. J Clin Apheresis 2000; 40: 961-967.
16. Ikeda K, Ohto H, Nemoto K, Yamamoto G, Kato K, Ogata T et al. Collection of MNCs and progenitor cells by two separators for PBPC transplantation: A randomized crossover trial. J Clin Apheresis 2003; 43: 814-819.
17. Lin J, Burgstaler EA, Pineda AA, Gertz MA. Effects of whole blood flow rates on mononuclear cell yields during peripheral blood stem cell collection using Fenwal CS3000 plus. J Clin Apheresis 1995; 10: 7-11.