Detection and characterization of hemopoietic stem cells in the adult human small intestine

Journal of Immunology

Volumn 176, Issue 9, 2006, Pages 5199-5204

  Lynch, Lydia ^a,b   O'Donoghue, Diarmuid ^a   Dean, Jonathan ^a   O'Sullivan, Jacintha ^a   O'Farrelly, Cliona ^a,b   Golden Mason, Lucy ^a  

^a ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; CD45 ANTIGEN; CD45RA ANTIGEN; STEM CELL FACTOR;

ADULT; AGED; ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL ISOLATION; CELL VIABILITY; CLINICAL ARTICLE; EPITHELIUM CELL; FEMALE; FLOW CYTOMETRY; GASTROINTESTINAL TRACT; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; LAMINA PROPRIA; LYMPHOID CELL; MALE; NATURAL KILLER CELL; PRIORITY JOURNAL; SAMPLING; SMALL INTESTINE MUCOSA; T LYMPHOCYTE ACTIVATION;

EID: 33646009680     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.176.9.5199     Document Type: Article

References (37)

1. Hayday, A., and R. Tigelaar. 2003. Immunoregulation in the tissues by γδ T cells. Nat. Rev. Immunol. 3: 233-242.
2. Treiner, E., L. Duban, S. Bahram, M. Radosavljevic, V. Wanner, F. Tilloy, P. Affaticati, S. Gilfillan, and O. Lantz. 2003. Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1. Nature 422: 164-169.
3. Jabri, B., N. P. de Serre, C. Cellier, K. Evans, C. Gache, C. Carvalho, J. F. Mougenot, M. Allez, R. Jian, P. Desreumaux, et al. 2000. Selective expansion of intraepithelial lymphocytes expressing the HLA-E-specific natural killer receptor CD94 in celiac disease. Gastroenterology 118: 867-879.
4. Leon, F., E. Roldan, L. Sanchez, C. Camarero, A. Bootello, and G. Roy. 2003. Human small-intestinal epithelium contains functional natural killer lymphocytes. Gastroenterology 5: 345-356.
5. - T lymphocytes in human small intestinal lamina propria. Eur. J. Gastroenterol. Hepatol. 10: 325-329.
6. 4-integrins in lymphocyte homing to mucosal tissue in vivo. J. Immunol. 152: 3282-3293.
7. Guy-Grand, D., and P. Vassalli. 2002. Gut intraepithelial lymphocyte development. Curr. Opin. Immunol. 14: 255-259.
8. 7, LEEP-CAM and chemokines. Curr. Opin. Immunol. 12: 563-568.
9. Olson, T. S., and K. Ley. 2002. Chemokines and chemokine receptors in leukocyte trafficking. Am. J. Physiol. Regulatory Integrative Comp Physiol. 283: R7-R28.
10. Abo, T., H. Watanabe, T. Iiai, M. Kimura, K. S. K. Ohtsuka, M. Ogawa, H. Hirahara, S. Hashimoto, H. Sekikawa and S. Seki. 1994. Extrathymic pathways of T cell differentiation in the liver and other organs. Int. Rev. Immunol. 11: 61-102.
11. Rocha, B., H. von Boehmer, and D. Guy-Grand. 1992. Selection of intraepithelial lymphocytes with CD8 co-receptors by self-antigen in the murine gut. Proc. Natl. Acad. Sci. USA 89: 5336-5340.
12. Saito, H., T. Kanayama, H. Takemori, E. Nariuchi, H. Kubota, T. Takahashi-Iwanaga, and H. Ishikawa. 1998. Generation of intestinal T cells from progenitors residing in gut cryptopatches. Science 280: 275-278.
13. Rocha, B., P. Vassalli, and D. Guy-Grand. 1992. The extrathymic T-cell development pathway. Immunol. Today 13: 449-454.
14. Laky, K., L. Lefrancois, E. G. Lingenheld, H. Ishikawa, J. M. Lewis, S. Olson, K. Suzuki, R. E. Tigelaar and L. Puddington. 2000. Enterocyte expression of interleukin 7 induces development of γδ T cells and Peyer's patches. J. Exp. Med. 191: 1569-1580.
15. Eberl, G., and D. R. Littman. 2004. Thymic origin of intestinal ab T cells revealed by fate mapping of RORγt+ cells. Science 305: 248-251.
16. Nonaka, S., T. Naito, H. Chen, M. Yamamoto, K. Moro, H. Kiyono, H. Hamada and H. Ishikawa. 2005. Intestinal γ δ T cells develop in mice lacking thymus, all lymph nodes, Peyer's patches, and isolated lymphoid follicles. J. Immunol. 174:1906-1912.
17. Arcangeli, M. L., C. Lacrin, F. Lambolez, C. Cordier, E. Schneider, B. Rocha, and S. Ezine. 2005. Extrathymic hemopoietic progenitors committed to T cell differentiation in the adult mouse. J. Immunol. 174: 1980-1988.
18. Kanamori, Y., K. Ishimaru, M. Nanno, K. Maki, K. Ikuta, H. Nariuchi, and H. Ishikawa. 1996. Identification of novel lymphoid tissues in murine intestinal mucosa where clusters of c-kit- IL-7R-Thy 1-lympho-hemopietic progenitors develop. J. Exp. Med. 184: 1449-1459.
19. Woodward, J., and E. Ienkinson. 2001. Identification and characterisation of lymphoid precursors in the murine intestinal epithelium. Eur. J. Immunol. 31: 3329-3338.
20. Lundqvist, C., V. Baranov, S. Hammarstrom, L. Athlin, and M. L. Hammarstrom. 1995. Intra epithelial lymphocytes. Evidence for regional specialization and extrathymic T cell maturation in the human gut epithelium. Int. Immunol. 7: 1473-1487.
21. Lynch, S., D. Kelleher, R. McManus, and C. O'Farrelly. 1995. RAG1 and RAG2 expression in human intestinal epithelium: evidence of extrathymic T cell differentiation. Eur. J. Immunol. 25: 1143-1147.
22. Watanabe, M., Y. Ueno, T. Yajima, Y. Iwao, M. Tsuchiya, H. Ishikawa, S. Aiso, T. Hibi, and H. Ishii. 1995. Interleukin 7 is produced by human intestinal epithelial cells and regulates the proliferation of intestinal mucosal lymphocytes. J. Clin. Invest. 95: 2945-2953.
23. Madrigal-Estebas, L., R. McManus, B. Byrne, S. Lynch, D. G. Doherty, D. Kelleher, D. P. O'Donoghue, C. Feighery, and C. O'Farrelly. 1997. Human small intestinal epithelial cells secrete interleukin-7 and differentially express two different interleukin-7 mRNA transcripts: implications for extrathymic T-cell differentiation. Hum. Immunol. 58: 83-90.
24. Plum, J., M. De Smed, G. Leclerc, B. Verhasselt, and B. Vanderckhove. 1996. Interleukin-7 is a critical growth factor in early human T-cell development. Blood 88: 4239-4245.
25. + T cell receptor-αβ cell development. J. Immunol. 159: 5931-5935.
26. Reinecker, H. C., R. P. MacDermott, S. Mirau, A. Dignass, and D. K. Podolsky. 1996. Intestinal epithelial cells both express and respond to interleukin 15. Gastroenterology. 111: 1706-1713.
27. Williams, A., P. W. Bland, A. C. Phillips, S. Turner, T. Brooklyn, G. Shaya, R. D. Spicer, and C. S. J. Probert. 2004. Intestinal αβ T cells differentiate and rearrange antigen receptor genes in situ in the human infant. J. Immunol. 173: 7190-7199.
28. Booth, C., and C. S. Potten. 2000. Gut instincts: thoughts on intestinal epithelial stem cells. J. Clin. Invest. 105: 1493-1499.
29. Till, J. E., and C. E. McCullagh. 1961. A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Radiat. Res. 14: 213-222.
30. Krause, D. S., M. J. Fackler, C. I. Civin, and W. S. May. 1996. CD34: structure, biology, and clinical utility. Blood 87: 1-13.
31. Lin, G., E. Finger, and J. C. Gutierrez-Ramos. 1995. Expression of CD34 in endothelial cells, hematopoietic progenitors and nervous cells in fetal and adult mouse tissues. Eur. J. Immunol. 25: 1508-1516.
32. Civin, C. I., and S. D. Gore. 1993. Antigenic analysis of hematopoiesis: a review. J. Hematotherapy. 2: 137-144.
33. Madrigal, L., S. Lynch, C. Feighery, D. G. Weir, D. Kelleher and C. O'Farrelly. 1993. Flow cytometric analysis of surface major histocompatibility complex class II expression on human epithelial cells prepared from small intestinal biopsies. J. Immunol. Methods 158: 207-214.
34. Crosbie, O. M., M. Reynolds, G. McEntee, O. Traynor, J. E. Hegarty and C. O'Farrelly. 1999. In vitro evidence for the presence of hematopoietic stem cells in the adult human liver. Hepatology. 29: 1193-1198.
35. Golden-Mason, L., M. P. Curry, N. Nolan, O. Traynor, G. McEntee, J. Kelly, J. E. Hegarty, and C. O'Farrelly. 2000. Differential expression of lymphoid and myeloid markers on differentiating hematopoietic stem cells in normal and tumor-bearing adult human liver. Hepatology. 31: 1251-1256.
36. + natural T cells with distinct cytotoxic activities and Th1, Th2, and Th0 cytokine secretion patterns. J. Immunol. 163: 2314-2321.
37. -/- mice: roles for both IL-2 and IL-15 in CD8αα IEL development. J. Immunol. 163: 5906-5912.