Importance of jararhagin disintegrin-like and cysteine-rich domains in the early events of local inflammatory response

Toxicon

Volumn 47, Issue 5, 2006, Pages 591-596

  Clissa, P B ^a   Lopes Ferreira, M ^a   Della Casa, M S ^a   Farsky, S H P ^b   Moura da Silva, A M ^a  

^a INSTITUTO BUTANTAN   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Bothrops jararaca venom; Disintegrin like cystein rich domain; Inflammation; Jararhagin

Indexed keywords

1,10 PHENANTHROLINE; COLLAGEN; CYSTEINE; DISINTEGRIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; JARARHAGIN C; METALLOPROTEINASE; SNAKE VENOM; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD FLOW VELOCITY; BLOOD VESSEL DIAMETER; CATALYSIS; CONTROLLED STUDY; CREMASTER MUSCLE; CYTOKINE RELEASE; ERYTHROCYTE; ILLUMINATION; IN VIVO STUDY; INFLAMMATION; LEUKOCYTE ROLLING; MICROVASCULATURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; SNAKE; THROMBOCYTE AGGREGATION INHIBITION; VENULE;

ANIMALS; BOTHROPS; CATALYTIC DOMAIN; CROTALID VENOMS; CYSTEINE; CYTOKINES; DISINTEGRINS; ENDOTHELIUM, VASCULAR; INFLAMMATION; INTERLEUKIN-6; LEUKOCYTE ROLLING; METALLOENDOPEPTIDASES; MICE; MUSCLE, SKELETAL; PLATELET AGGREGATION INHIBITORS; TIME FACTORS; VENULES;

ANIMALIA; BOTHROPS JARARACA;

EID: 33645998091     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2006.02.001     Document Type: Article

References (24)

1. Baramova E.N., Shannon J.D., Bjarnason J.B., and Fox J.W. Degradation of extracellular matrix proteins by hemorrhagic metalloproteinases. Arch. Biochem. Biophys. 275 1 (1989) 63-71
2. Bjarnason J.B., and Fox J.W. Hemorrhagic metalloproteinases from snake venoms. Pharmacol. Ther. 62 (1994) 325-372
3. Clissa P.B., Laing G.D., Theakston R.D., Mota I., Taylor M.J., and Moura-da-Silva A.M. The effect of jararhagin, a metalloproteinase from Bothrops jararaca venom, on pro-inflammatory cytokines released by murine peritoneal adherent cells. Toxicon 39 (2001) 1567-1573
4. Costa E.P., Clissa P.B., Teixeira C.F., and Moura-da-Silva A.M. Importance of metalloproteinases and macrophages in viper snake envenomation-induced local inflammation. Inflammation 26 (2002) 13-17
5. Dahlen S.E., Bjork J., Hedqvist P., Arfors K.E., Hammarstrom S., Lindgren J.A., and Samuelsson B. Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response. Proc. Natl Acad. Sci. USA 78 6 (1981) 3887-3891
6. De Luca M., Ward C.M., Ohmori K., Andrews R.K., and Berndt M.C. Jararhagin and jaracetin: novel snake venom inhibitors of the integrin collagen receptor, alpha 2 beta 1. Biochem. Biophys. Res. Commun. 206 (1995) 570-576
7. Gallagher P., Bao Y., Serrano S.M., Laing G.D., Theakston R.D., Gutierrez J.M., Escalante T., Zigrino P., Moura-da-Silva A.M., Nischt R., Mauch C., Moskaluk C., and Fox J.W. Role of the snake venom toxin jararhagin in proinflammatory pathogenesis: in vitro and in vivo gene expression analysis of the effects of the toxin. Arch. Biochem. Biophys. 441 (2005) 1-15
8. Ivaska J., Kapyla J., Pentikainen O., Hoffren A.M., Hermonen J., Huttunen P., Johnson M.S., and Heino J. A peptide inhibiting the collagen binding function of integrin alpha2I domain. J. Biol. Chem. 274 (1999) 3513-3521
9. Kamiguti A.S., Hay C.R., and Zuzel M. Inhibition of collagen-induced platelet aggregation as the result of cleavage of alpha 2 beta 1-integrin by the snake venom metalloproteinase jararhagin. Biochem. J. 320 Pt 2 (1996) 635-641
10. Kamiguti A.S., Moura-da-Silva A.M., Laing G.D., Knapp T., Zuzel M., Crampton J.M., and Theakston R.D. Collagen-induced secretion-dependent phase of platelet aggregation is inhibited by the snake venom metalloproteinase jararhagin. Biochim. Biophys. Acta. 1335 (1997) 209-217
11. Kamiguti A.S., Gallagher P., Marcinkiewicz C., Theakston R.D., Zuzel M., and Fox J.W. Identification of sites in the cysteine-rich domain of the class P-III snake venom metalloproteinases responsible for inhibition of platelet function. FEBS Lett. 549 (2003) 129-134
12. Laing G.D., and Moura-da-Silva A.M. Jararhagin and its multiple effects on hemostasis. Toxicon 45 (2005) 987-996
13. Laing G.D., Clissa P.B., Theakston R.D., Moura-da-Silva A.M., and Taylor M.J. Inflammatory pathogenesis of snake venom metalloproteinase-induced skin necrosis. Eur. J. Immunol. 33 (2003) 3458-3463
14. Lomonte B., Lundgren J., Johansson B., and Bagge U. The dynamics of local tissue damage induced by Bothrops asper snake venom and myotoxin II on the mouse cremaster muscle: an intravital and electron microscopic study. Toxicon 32 (1994) 41-55
15. Mariano-Oliveira A., Coelho A.L., Terruggi C.H., Selistre-de-Araujo H.S., Barja-Fidalgo C., and De Freitas M.S. Alternagin-C, a non RGD-disintegrin, induces neutrophil migration via integrin signaling. Eur. J. Biochem. 270 (2003) 4799-4808
16. Moura-da-Silva A.M., Laing G.D., Paine M.J., Dennison J.M., Politi V., Crampton J.M., and Theakston R.D. Processing of pro-tumor necrosis factor-alpha by venom metalloproteinases: a hypothesis explaining local tissue damage following snake bite. Eur. J. Immunol. 26 (1996) 2000-2005
17. Moura-da-Silva A.M., Linica A., Della-Casa M.S., Kamiguti A.S., Ho P.L., Crampton J.M., and Theakston R.D. Jararhagin ECD-containing disintegrin domain: expression in Escherichia coli and inhibition of the platelet-collagen interaction. Arch. Biochem. Biophys. 369 (1999) 295-301
18. Moura-da-Silva A.M., Marcinkiewicz C., Marcinkiewicz M., and Niewiarowski S. Selective recognition of alpha2beta1 integrin by jararhagin, a metalloproteinase/disintegrin from Bothrops jararaca venom. Thromb. Res. 102 (2001) 153-159
19. Moura-da-Silva A.M., Della-Casa M.S., David A.S., Assakura M.T., Butera D., Lebrun I., Shannon J.D., Serrano S.M., and Fox J.W. Evidence for heterogeneous forms of the snake venom metalloproteinase jararhagin: a factor contributing to snake venom variability. Arch. Biochem. Biophys. 409 (2003) 395-401
20. Paine M.J., Desmond H.P., Theakston R.D., and Crampton J.M. Purification, cloning, and molecular characterization of a high molecular weight hemorrhagic metalloprotease, jararhagin, from Bothrops jararaca venom. Insights into the disintegrin gene family. J. Biol. Chem. 267 (1992) 22869-22876
21. Pentikainen O., Hoffren A.M., Ivaska J., Kapyla J., Nyronen T., Heino J., and Johnson M.S. 'RKKHlsquo; peptides from the snake venom metalloproteinase of Bothrops jararaca bind near the metal ion-dependent adhesion site of the human integrin alpha(2) I-domain. J. Biol. Chem. 274 (1999) 31493-31505
22. Rucavado A., Nunez J., and Gutierrez J.M. Blister formation and skin damage induced by BaP1, a hemorrhagic metalloproteinase from the venom of the snake Bothrops asper. Int. J. Exp. Pathol. 79 (1998) 245-254
23. Souza D.H.F., Iemma M.R.C., Ferreira L.L., Faria J.P., Oliva M.L.V., Zingali R.B., Niewiarowski S., and Selistre-de-Araújo H.S. The disintegrin-like domain of the snake venom metalloprotease alternagin inhibits α2β1integrin-mediated cell adhesion. Arch. Biochem. Biophys. 384 (2000) 341-350
24. Tanjoni I., Weinlich R., Della-Casa M.S., Clissa P.B., Saldanha-Gama R.F., Freitas M.S., Barja-Fidalgo C., Amarante-Mendes G.P., and Moura-da-Silva A.M. Jararhagin, a snake venom metalloproteinase, induces a specialized form of apoptosis (anoikis) selective to endothelial cells. Apoptosis 10 (2005) 851-861