Immune responses to commercial equine vaccines against equine herpesvirus-1, equine influenza virus, eastern equine encephalomyelitis, and tetanus

Veterinary Immunology and Immunopathology

Volumn 111, Issue 1-2, 2006, Pages 67-80

  Holmes, Mark A ^a   Townsend, Hugh G G ^b   Kohler, Andrea K ^c   Hussey, Steve ^c   Breathnach, Cormac ^d   Barnett, Craig ^e   Holland, Robert ^e   Lunn, D P ^c  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

^c Department of Environmental and Radiological Health Sciences   (United States)

^d UNIVERSITY OF KENTUCKY   (United States)

^e MERCK ANIMAL HEALTH   (United States)

Author keywords

Horses; Infectious disease; Vaccination

Indexed keywords

CALVENZA; GAMMA INTERFERON; MESSENGER RNA; VACCINE;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGENICITY; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; EASTERN EQUINE ENCEPHALOMYELITIS VIRUS; EQUINE HERPES VIRUS; FEMALE; HORSE; IMMUNE RESPONSE; IMMUNITY; INFLUENZA VIRUS; NONHUMAN; RESPIRATORY TRACT DISEASE; SEROLOGY; TETANUS; UNITED STATES; VIRUS INFECTION;

ANIMALS; ANTIBODIES, VIRAL; CLOSTRIDIUM TETANI; DNA, VIRAL; ENCEPHALITIS VIRUS, EASTERN EQUINE; ENCEPHALOMYELITIS, EQUINE; FEMALE; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 1, EQUID; HORSE DISEASES; HORSES; IMMUNOASSAY; INFLUENZA A VIRUS, H3N8 SUBTYPE; INTERFERON TYPE II; NEUTRALIZATION TESTS; ORTHOMYXOVIRIDAE INFECTIONS; POLYMERASE CHAIN REACTION; TETANUS; VIRAL VACCINES;

ANIMALIA; EASTERN EQUINE ENCEPHALITIS VIRUS; EQUID HERPESVIRUS 1; EQUIDAE; EQUINE INFLUENZA VIRUS; EQUUS CABALLUS; ORTHOMYXOVIRIDAE;

EID: 33645995755     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetimm.2006.01.010     Document Type: Article

References (50)

1. Allen G.P., Kydd J.H., Slater J.D., and Smith K.C. Equid herpesvirus-1 and equid herpesvirus-4 infections. In: Coetzer J.A., and W.T. R.C. (Eds). Infectious Diseases of Livestock (2004), Oxford University Press, Newmarket 829-859
2. Atwill E.R., and Mohammed H.O. Benefit-cost analysis of vaccination of horses as a strategy to control equine monocytic ehrlichiosis. J. Am. Vet. Med. Assoc. 208 (1996) 1295-1299
3. Atwill E.R., and Mohammed H.O. Evaluation of vaccination of horses as a strategy to control equine monocytic ehrlichiosis. J. Am. Vet. Med. Assoc. 208 (1996) 1290-1294
4. Bogdan J.R., Morley P.S., Townsend H.G.G., and Haines D.M. Effect of influenza A/equine/H3N8 virus isolate variation on the measurement of equine antibody responses. Can. J. Vet. Res. Rev. Rev. Can. Rech. Vet. 57 (1993) 126-130
5. Borchers K., and Slater J. A nested PCR for the detection and differentiation of EHV-1 and EHV-4. J. Virol. Methods 45 (1993) 331-336
6. Breathnach C.C., Rudersdorf R., and Lunn D.P. Use of recombinant modified vaccinia Ankara viral vectors for equine influenza vaccination. Vet. Immunol. Immunopathol. 98 (2004) 127-136
7. Breathnach C.C., Soboll G., Suresh M., and Lunn D.P. Equine herpesvirus-1 infection induces IFN-gamma production by equine T lymphocyte subsets. Vet. Immunol. Immunopathol. 103 (2005) 207-215
8. Chong Y.C., and Duffus W.P. Immune responses of specific pathogen free foals to EHV-1 infection. Vet. Microbiol. 32 (1992) 215-228
9. Cullinane A., Weld J., Osborne M., Nelly M., McBride C., and Walsh C. Field studies on equine influenza vaccination regimes in thoroughbred foals and yearlings. Vet. J. 161 (2001) 174-185
10. Dolby C.A., Hannant D., and Mumford J.A. Response of ponies to adjuvanted EHV-1 whole virus vaccine and challenge with virus of the homologous strain. Br. Vet. J. 151 (1995) 27-37
11. Edington N., Welch H.M., and Griffiths L. The prevalence of latent equid herpesviruses in the tissues of 40 abattoir horses. Equine Vet. J. 26 (1994) 140-142
12. Foote C.E., Love D.N., Gilkerson J.R., and Whalley J.M. Serological responses of mares and weanlings following vaccination with an inactivated whole virus equine herpesvirus-1 and equine herpesvirus-4 vaccine. Vet. Microbiol. 88 (2002) 13-25
13. Foote C.E., Love D.N., Gilkerson J.R., and Whalley J.M. Detection of EHV-1 and EHV-4 DNA in unweaned Thoroughbred foals from vaccinated mares on a large stud farm. Equine Vet. J. 36 (2004) 341-345
14. Franklin R.P., Kinde H., Jay M.T., Kramer L.D., Green E.G., Chiles R.E., Ostlund E., Husted S., Smith J., and Parker M.D. Eastern equine encephalomyelitis virus infection in a horse from California. Emerg. Infect. Dis. 8 (2002) 283-288
15. Gilkerson J.R., Whalley J.M., Drummer H.E., Studdert M.J., and Love D.N. Epidemiological studies of equine herpesvirus-1 (EHV-1) in thoroughbred foals: a review of studies conducted in the Hunter Valley of New South Wales between 1995 and 1997. Vet. Microbiol. 68 (1999) 15-25
16. Green S.L., Little C.B., Baird J.D., Tremblay R.R., and Smith-Maxie L.L. Tetanus in the horse: a review of 20 cases (1970 to 1990). J. Vet. Intern. Med. 8 (1994) 128-132
17. Hannant D., Jessett D.M., O'Neill T., Dolby C.A., Cook R.F., and Mumford J.A. Responses of ponies to equid herpesvirus-1 ISCOM vaccination and challenge with virus of the homologous strain. Res. Vet. Sci. 54 (1993) 299-305
18. Hannant D., Mumford J.A., and Jessett D.M. Duration of circulating antibody and immunity following infection with equine influenza virus. Vet. Rec. 122 (1988) 125-128
19. Hays M.B. Definitive efficacy and safety testing for equine encephalomyelitis vaccine. J. Am. Vet. Med. Assoc. 155 (1969) 374-376
20. Heldens J.G., Hannant D., Cullinane A.A., Prendergast M.J., Mumford J.A., Nelly M., Kydd J.H., Weststrate M.W., and van den Hoven R. Clinical and virological evaluation of the efficacy of an inactivated EHV1 and EHV4 whole virus vaccine (Duvaxyn EHV1, 4). Vaccination/challenge experiments in foals and pregnant mares. Vaccine 19 (2001) 4307-4317
21. Heldens J.G., Kersten A.J., Weststrate M.W., and van den Hoven R. Duration of immunity induced by an adjuvanted and inactivated equine influenza, tetanus and equine herpesvirus-1 and -4 combination vaccine. Vet. Q. 23 (2001) 210-217
22. Heldens J.G., Van de Wouw J.C.A., and Van Loon A.A.W.M. An updated equine influenza vaccine and an equine influenza-herpesvirus combination vaccine containing an Immunostim adjuvant provoke equal antibody levels in young foals throughout the primary vaccination course. Vet. J. 164 (2002) 288-291
23. Jansen B.C., and Knoetze P.C. The immune response of horses to tetanus toxoid. Onderstepoort J. Vet. Res. 46 (1979) 211-216
24. Kydd J.H., and Antczak D.F. First International Workshop on equine leucocyte antigens 12th-13th July, 1991: preliminary report. Equine Vet. J. Suppl. 12 (1991) 4-6
25. Kydd J.H., Townsend H.G.G., and Hannant D. The equine immune response to equine herpesvirus-1: the virus and its vaccines. Vet. Immunol. Immunopathol. 111 (2006) 15-30
26. Kydd J.H., Wattrang E., and Hannant D. Pre-infection frequencies of equine herpesvirus-1 specific, cytotoxic T-lymphocytes correlate with protection against abortion following experimental infection of pregnant mares. Vet. Immunol. Immunopathol. 96 (2003) 207-217
27. Liefman C.E. Active immunisation of horses against tetanus including the booster dose and its application. Aust. Vet. J. 57 (1981) 57-60
28. Lunn D.P., Hussey S., Sebring R., Rushlow K.E., Radecki S.V., Whitaker-Dowling P., Youngner J.S., Chambers T.M., Holland R.E., and Horohov D.W. Safety, efficacy, and immunogenicity of a modified-live equine influenza virus vaccine in horses after induction of exercise-induced immunosuppression. J. Am. Vet. Med. Assoc. 218 (2001) 900-906
29. Lunn D.P., and Townsend H.G.G. Equine vaccination. Vet. Clin. North Am. Equine Pract. 16 (2000) 199-226
30. Morley P.S., Hanson L.K., Bogdan J.R., Townsend H.G., Appleton J.A., and Haines D.M. The relationship between single radial hemolysis, hemagglutination inhibition, and virus neutralization assays used to detect antibodies specific for equine influenza viruses. Vet. Microbiol. 45 (1995) 81-92
31. Morley P.S., Townsend H.G.G., Bodgan J.R., and Haines D.M. Efficacy of a commercial vaccine for preventing disease caused by influenza virus infection in horses. J. Am. Vet. Med. Assoc. 215 (1999) 61-66
32. Morley P.S., Townsend H.G.G., Bodgan J.R., and Haines D.M. Risk factors for disease associated with influenza virus infections during three epidemics in horses. J. Am. Vet. Med. Assoc. 216 (2000) 545-550
33. Mumford E.L., Traub-Dargatz J., Carman J., Callan R., Collins J.K., Goltz K.L., Romm S.R., Tarr S.F., and Salman M.D. Occurrence of infectious upper respiratory tract disease and response to vaccination in horses on six sentinel premises in northern Colarado. Equine Vet. J. 35 (2003) 72-77
34. Mumford E.L., Traub-Dargatz J.L., Salman M.D., Collins J.K., Getzy D.M., and Carman J. Monitoring and detection of acute viral respiratory tract disease in horses. J. Am. Vet. Med. Assoc. 213 (1998) 385-390
35. Mumford J.A., and Bates J. Trials of an inactivated equid herpesvirus-1 vaccine: challenge with a subtype 2 virus. Vet. Rec. 114 (1984) 375-381
36. Mumford J.A., Hannant D., Jesett D.M., and O'Neill T. Evaluation of protective efficacy of Equid herpes virus type I ISCOM vaccine for the abortigenic form of disease. J. Reprod. Fertil. Suppl. 44 (1991) 730-731
37. Mumford J.A., Hannant D., and Jessett D.M. Experimental infection of ponies with equine influenza (H3N8) viruses by intranasal inoculation or exposure to aerosols. Equine Vet. J. 22 (1990) 93-98
38. Mumford J.A., Wilson H., Hannant D., and Jessett D.M. Antigenicity and immunogenicity of equine influenza vaccines containing a Carbomer adjuvant. Epidemiol. Infect. 112 (1994) 421-437
39. Mumford J.A., and Wood J. Establishing an acceptability threshold for equine influenza vaccines. Dev. Biol. Stand. 79 (1992) 137-146
40. Nelson K.M., Schram B.R., McGregor M.W., Sheoran A.S., Olsen C.W., and Lunn D.P. Local and systemic isotype-specific antibody responses to equine influenza virus infection versus conventional vaccination. Vaccine 16 (1998) 1306-1313
41. O'Neill T., Kydd J.H., Allen G.P., Wattrang E., Mumford J.A., and Hannant D. Determination of equid herpesvirus-1-specific, CD8+, cytotoxic T-lymphocyte precursor frequencies in ponies. Vet. Immunol. Immunopathol. 70 (1999) 43-54
42. Ostlund E.N. The equine herpesviruses. Vet. Clin. North Am. Equine Pract. 9 (1993) 283-294
43. Paillot R., Daly J.M., Juillard V., Minke J.M., Hannant D., and Kydd J.H. Equine interferon gamma synthesis in lymphocytes after in vivo infection and in vitro stimulation with EHV-1. Vaccine 23 (2005) 4541-4551
44. Roberts M.C. Equine immunoglobulins and the equine immune system. In: Grunsell C.S.G., and Hill F.W.G. (Eds). The Veterinary Annual (1975), Wright-Scientifica, Bristol 192-203
45. Ross W.A., and Kaneene J.B. Evaluation of outbreaks of disease attributable to eastern equine encephalitis virus in horses. J. Am. Vet. Med. Assoc. 208 (1996) 1988-1997
46. Sheoran A.S., Timoney J.F., Holmes M.A., Karzenski S.S., and Crisman M.V. Immunoglobulin isotypes in sera and nasal mucosal secretions and their neonatal transfer and distribution in horses. Am. J. Vet. Res. 61 (2000) 1099-1105
47. Townsend H.G., Penner S.J., Watts T.C., Cook A., Bogdan J., Haines D.M., Griffin S., Chambers T., Holland R.E., Whitaker-Dowling P., Youngner J.S., and Sebring R.W. Efficacy of a cold-adapted, intranasal, equine influenza vaccine: challenge trials. Equine Vet. J. 33 (2001) 637-643
48. Townsend H.G.G., Morley P.S., and Newton J.R. Measuring serum antibody as a method of predicting infection and disease in horses during outbreaks of influenza. In: Wernery U., Wade J.F., Mumford J.A., and Kaaden O.-R. (Eds). Equine Infectious Diseases VIII. Proceedings of the Eighth International Conference, Dubai 23-26 March 1998 (1999), R&W Publications, Newmarket 33-37
49. Wilson W.D., Kanara E., Spensley M.S., Powell D.G., Files W.S., and Steckel R.R. Guidelines for vaccination of horses. J. Am. Vet. Med. Assoc. 207 (1995) 426-431
50. Wilson W.D., Mihalyi J.E., Hussey S., and Lunn D.P. Passive transfer of maternal immunoglobulin isotype antibodies against tetanus and influenza and their effect on the response of foals to vaccination. Equine Vet. J. 33 (2001) 644-650