Reconstruction of liver organoid using a bioreactor

World Journal of Gastroenterology

Volumn 12, Issue 12, 2006, Pages 1881-1888

  Saito, Masaya ^a   Matsuura, Tomakazu ^a   Masaki, Takahiro ^b   Maehashi, Haruka ^a   Shimizu, Keiko ^a   Hataba, Yoshiaki ^a   Iwahori, Tohru ^c   Suzuki, Tetsuro ^b   Braet, Filip ^d  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^c TOKYO MEDICAL UNIVERSITY   (Japan)

^d UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Bioartificial liver; Coculture; Fenestrae; Hepatocytes; Liver organoid; Liver sinusoidal endothelial cell; Organ reconstruction; Radial flow bioreactor; Vesiculo vacuolar organelles

Indexed keywords

ALBUMIN; ARGINASE; ARGININOSUCCINATE SYNTHASE; CELLULOSE; MESSENGER RNA; SWINHOLIDE A; UREA;

ANIMAL CELL; ARTICLE; BIOARTIFICIAL LIVER; BIOREACTOR; CANCER CELL CULTURE; CELL ADHESION; CELL COUNT; CELL FUNCTION; CELL IMMORTALIZATION; CELL ORGANELLE; CELL STRUCTURE; CELL SURFACE; CELL TYPE; COCULTURE; CONTROLLED STUDY; CULTURE MEDIUM; ENDOTHELIUM CELL; ENZYME SYNTHESIS; FOLLOW UP; GENETIC CODE; HUMAN; HUMAN CELL; INCUBATION TIME; INTRAHEPATIC BILE DUCT; LIVER CELL CARCINOMA; LIVER DISEASE; LIVER FUNCTION; LIVER PARENCHYMA; LIVER SINUSOID; MONOLAYER CULTURE; MOUSE; NONHUMAN; PERFUSION; PROTEIN EXPRESSION; SCANNING ELECTRON MICROSCOPY; STELLATE CELL; TRANSMISSION ELECTRON MICROSCOPY; UREA CYCLE; VESTIBULE;

EID: 33645989124     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v12.i12.1881     Document Type: Article

References (32)

1. Gordon GJ, Butz GM, Grisham JW, Coleman WB. Isolation, short-term culture, and transplantation of small hepatocyte like progenitor cells from retrorsine-exposed rats. Transplantation 2002; 73: 1236-1243
2. Kanda T, Watanabe S, Yoshiike K. Immortalization of primary rat cells by human papillomavirus type 16 subgenomic DNA fragments controlled by the SV40 promoter. Virology 1988; 165: 321-325
3. Nishida K, Yamato M, Hayashida Y, Watanabe K, Yamamoto K, Adachi E, Nagai S, Kikuchi A, Maeda N, Watanabe H, Okano T, Tano Y. Corneal reconstruction with tissue-engineered cell sheets composed of autologous oral mucosal epithelium. N Engl J Med 2004; 351: 1187-1196
4. Nishida K, Yamamoto M, Hayashida Y. Corneal reconstruction using tissue-engineered cell sheets comprising autologous oral mucosal epithelium. N Engl J Med 2004; 351: 1187-1196
5. Tabata Y. Tissue regeneration based on growth factor release. Tissue Eng 2003; 9 Suppl 1: S5-S15
6. Sussman NL, Chong MG, Koussayer T, He DE, Shang TA, Whisennand HH, Kelly JH. Reversal of fulminant hepatic failure using an extracorporeal liver assist device. Hepatology 1992; 16: 60-65
7. Sussman NL, Kelly JH. Improved liver function following treatment with an extracorporeal liver assist device. Artif Organs 1993; 17: 27-30
8. Matsuura T, Kawada M, Hasumura S, Nagamori S, Obata T, Yamaguchi M, Hataba Y, Tanaka H, Shimizu H, Unemura Y, Nonaka K, Iwaki T, Kojima S, Aizaki H, Mizutani S, Ikenaga H. High density culture of immortalized liver endothelial cells in the radial-flow bioreactor in the development of an artificial liver. Int J Artif Organs 1998; 21: 229-234
9. Matsuura T, Kawada M, Sujino H, Hasumura S, Nagamori S, Shimizu H. Vitamin A metabolism of immortalized hepatic stellate cell in the bioreactor. In: Wisse E, Knock D L, De Zanger R, Arthur M J P, eds. Cells of the Hepatic Sinusoid 7. Leiden: Kupffer Cell Foundation, 1999: 88-89
10. Jat PS, Noble MD, Atahotis P, Tanaka Y, Yannoutsos N, Larsen L, Kioussis D. Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse. Proc Natl Acad Sci USA 1991; 88: 5096-5100
11. Wisse E. An electron microscopic study of the fenestrated endothelial lining of rat liver sinusoids. J Ultrastruct Res 1970; 31: 125-150
12. Braet F. How molecular microscopy revealed new insights into the dynamics of hepatic endothelial fenestrae in the past decade. Liver Int 2004; 24: 532-539
13. Fraser R, Dobbs BR, Rogers GW. Lipoproteins and the liver sieve: the role of the fenestrated sinusoidal endothelium in lipo-protein metabolism, atherosclerosis, and cirrhosis. Hepatology 1995; 21: 863-874
14. Braet F, Spector I, De Zanger R, Wisse E. A novel structure involved in the formation of liver endothelial cell fenestrae revealed by using the actin inhibitor misakinolide. Proc Natl Acad Sci USA 1998; 95: 13635-13640
15. Braet F, Spector I, Shochet N, Crews P, Higa T, Menu E, de Zanger R, Wisse E. The new anti-actin agent dihydrohalichon-dramide reveals fenestrae-forming centers in hepatic endothelial cells. BMC Cell Biol 2002; 3: 7
16. Oda M, Tsukada N, Komatsu H, Kaneko K, Nakamura M, Tsuchiya M: Electron microscopic localizations of actin, cal-modulin and calcium in the hepatic sinusoidal endothelium in the rat. In: Kirn A, Knook DL, Wisse E des. Cells of the Hepatic Sinusoid 1. Rijswijk, Kupffer Cell Foundation 1986, 511-512
17. Gatmaitan Z, Varticovski L, Ling L, Mikkelsen R, Steffan AM, Arias IM. Studies on fenestral contraction in rat liver endothelial cells in culture. Am J Pathol 1996; 148: 2027-2041
18. Kawada M, Nagamori S, Aizaki H, Fukaya K, Niiya M, Matsuura T, Sujino H, Hasumura S, Yashida H, Mizutani S, Ikenaga H. Massive culture of human liver cancer cells in a newly developed radial flow bioreactor system: ultrafine structure of functionally enhanced hepatocarcinoma cell lines. In Vitro Cell Dev Biol Anim 1998; 34: 109-115
19. Aizaki H, Nagamori S, Matsuda M, Kawakami H, Hashimoto O, Ishiko H, Kawada M, Matsuura T, Hasumura S, Matsuura Y, Suzuki T, Miyamura T. Production and release of infectious hepatitis C virus from human liver cell cultures in the three-dimensional radial-flow bioreactor. Virology 2003; 314: 16-25
20. Braet F, de Zanger R, Seynaeve C, Baekeland M, Wisse E. A comparative atomic force microscopy study on living skin fibroblasts and liver endothelial cells. J Electron Microsc (Tokyo) 2001; 50: 283-290
21. Feng D, Nagy JA, Hipp J, Dvorak HF, Dvorak AM. Vesiculo-vacuolar organelles and the regulation of venule permeability to macromolecules by vascular permeability factor, histamine, and serotonin. J Exp Med 1996; 183: 1981-1986
22. Feng D, Nagy JA, Pyne K, Hammel I, Dvorak HF, Dvorak AM. Pathways of macromolecular extravasation across mirovascular endothelium in response to VPF/VEGF and other vasoactive mediators. Microcirculation 1999; 6: 23-44
23. Yokomori H, Oda M, Yoshimura K, Nagai T, Ogi M, Nomura M, Ishii H. Vascular endothelial growth factor increases fenestral permeability in hepatic sinusoidal endothelial cells. Liver Int 2003; 23: 467-475
24. Oda M, Yokomori H, Han J Y, Kamegaya Y, Ogi M, Nakamura M. Hepatic sinusoidal endothelial fenestrae are a stationary type of fused and interconnected caveolae. In: Wisse E, Knook D L, De Zanger R, Arthur M J P, eds. Cells of the Hepatic Sinusoid 8. Leiden: Kupffer Cell Foundation, 2001: 94-98
25. Nagamori S, Hasumura S, Matsuura T, Aizaki H, Kawada M. Developments in bioartificial liver research: concepts, performance, and applications. J Gastroenterol 2000; 35: 493-503
26. Iwahori T, Matsuura T, Maehashi H, Sugo K, Saito M, Hosokawa M, Chiba K, Masaki T, Aizaki H, Ohkawa K, Suzuki T. CYP3A4 inducible model for in vitro analysis of human drug metabolism using a bioartificial liver. Hepatology 2003; 37: 665-673
27. Li MX, Nakajima T, Fukushige T, Kobayashi K, Seiler N, Saheki T. Aberrations of ammonia metabolism in ornithine carbamoyltransferase-deficient spf-ash mice and their prevention by treatment with urea cycle intermediate amino acids and an ornithine aminotransferase inactivator. Biochim Biophys Acta 1999; 1455: 1-11
28. Glicklis R, Merchuk JC, Cohen S. Modeling mass transfer in hepatocyte spheroids via cell viability, spheroid size, and hepatocellular functions. Biotechnol Bioeng 2004; 86: 672-680
29. Ma M, Xu J, Purcell WM. Biochemical and functional changes of rat liver spheroids during spheroid formation and maintenance in culture: I. morphological maturation and kinetic changes of energy metabolism, albumin synthesis, and activities of some enzymes. J Cell Biochem 2003; 90: 1166-1175
30. MacSween R.N.M. Pathology of the Liver, 4th ed. In: Developmental anatomy and normal structure, Churchill Livingstone, 2002: 16-22
31. Matsumoto T, Komori R, Magara T, Ui T, Kawakami M, Hano H. A study on the normal structure of the human liver, with special reference to its angioarchitecture. Jikei Med J 1979; 26: 1-40
32. Ishida Y, Smith S, Wallace L, Sadamoto T, Okamoto M, Auth M, Strazzabosco M, Fabris L, Medina J, Prieto J, Strain A, Neuberger J, Joplin R. Ductular morphogenesis and functional polarization of normal human biliary epithelial cells in three-dimensional culture. J Hepatol 2001; 35: 2-9