Assessment of induction of cytochrome P450 by NO-1886 (ibrolipim), a lipoprotein lipase-promoting agent, in primary cultures of human hepatocytes and in female rat liver.

Drug metabolism and pharmacokinetics

Volumn 21, Issue 1, 2006, Pages 19-28

  Morioka, Yujiro ^a   Nishimura, Masuhiro ^a   Imai, Teruko ^a   Suzuki, Satoshi ^a   Harada, Miwa ^a   Satoh, Tetsuo ^a   Naito, Shinsaku ^a  

^a OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 [(4 BROMO 2 CYANOPHENYL)CARBAMOYL]BENZYLPHOSPHONIC ACID DIETHYL ESTER; 4-DIETHOXYPHOSPHORYLMETHYL-N-(4-BROMO-2-CYANOPHENYL)BENZAMIDE; BENZAMIDE DERIVATIVE; CYTOCHROME P450; ISOENZYME; LIPOPROTEIN LIPASE; MESSENGER RNA; ORGANOPHOSPHORUS COMPOUND;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECT; ENZYME INDUCTION; ENZYMOLOGY; FEMALE; GENETICS; HUMAN; IN VITRO STUDY; LIVER; LIVER CELL; LIVER MICROSOME; METABOLISM; POLYACRYLAMIDE GEL ELECTROPHORESIS; RAT; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

ANIMALS; BENZAMIDES; BLOTTING, WESTERN; CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INDUCTION; FEMALE; HEPATOCYTES; HUMANS; ISOENZYMES; LIPOPROTEIN LIPASE; LIVER; MICROSOMES, LIVER; ORGANOPHOSPHORUS COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 33645986147     PISSN: 13474367     EISSN: None     Source Type: Journal    
DOI: 10.2133/dmpk.21.19     Document Type: Article

References (0)