New cassaine diterpenoid amides with cytotoxic activities from the bark of Erythrophleum fordii

Planta Medica

Volumn 72, Issue 5, 2006, Pages 442-449

  Qu, Jing ^a   Hu, You Cai ^a   Yu, Shi Shan ^a,b   Chen, Xiao Guang ^a   Li, Yan ^a  

^a PEKING UNION MEDICAL COLLEGE   (China)

^b INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Cassaine diterpenoid amides; Cytotoxic activities; Erythrophleum fordii; Leguminosae

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 3BETA ACETYLNORERYTHROPHLAMIDE; 3BETA TIGLOYLNORERYTHROPHLAMIDE; 6ALPHA HYDROXYNORCASSAMIDE; 6ALPHA HYDROXYNORCASSAMIDE 22 O BETA DEXTRO GALACTOPYRANOSIDE; 7 DEHYDRONORERYTHROSUAMIDE; AMIDE; CASSAINE DITERPENOID AMIDE; CYTOTOXIC AGENT; DITERPENOID; ERYTHROPHLEUM FORDII EXTRACT; GALACTOSE; NEW DRUG; NORCASSAMIDE; NORERYTHROSUAMIDE; NORERYTHROSUAMIDE 22 O BETA DEXTRO GALACTOPYRANOSIDE; PLANT MEDICINAL PRODUCT; PYRANOSIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CHINESE HERB; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; ERYTHROPHLEUM FORDII; HUMAN; HUMAN CELL; IC 50; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; PHYTOCHEMISTRY;

ALKALOIDS; AMIDES; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; DITERPENES; FABACEAE; HUMANS; PHYTOTHERAPY; PLANT BARK; PLANT EXTRACTS;

ERYTHROPHLEUM; FABACEAE; MINK CELL FOCUS-FORMING VIRUS;

EID: 33645985840     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-916264     Document Type: Article

References (11)

1. Cronlund A. New alkaloids from Erythrophleum species. Planta Med 1973; 24: 371-4
2. Verotta L, Aburjai T, Rogers CB, Dorigo P, Maragno I, Fraccarollo D et al. Chemical and pharmacological characterization of Erythrophleum lasianthum alkaloids. Planta Med 1995; 61: 271-4
3. Yu F, Li N, Yu SS. A new diterpenoid glucopyranoside from Erythrophleum fordii. J Asian Nat Prod Res 2005; 7: 19-24
4. Li N, Yu F, Yu SS. Triterpenoids from Erythrophleum fordii. Acta Bot Si 2004; 46: 371-4
5. Oshima R, Kumanotani J. Determination of configuration of monosaccharides by HPLC on diastereoisomeric 1-deoxy-1-(N-acetyl-α-methylbenzylamino) alditol acetates. Chem Lett 1981; 10: 943-6
6. Alley MC, Scudiero DA, Monks A, Hursey ML, Czerwinski MJ, Fine DL et al. Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay. Cancer Res 1988; 48: 589-601
7. Clarke RL. Erythrophleum alkaloids. Phytochemistry 1971; 10: 851-6
8. Loder JW, Culvenor CCJ, Nearn RH, Russell GB, Stanton DW. Isolation of norcassamidide and authentic norcassamidine from Erythrophleum chlorostachys. Structural revision of the alkaloids previously known as norcassamidine, norcassamine, norethythrosuamine and dehydro-norerythrosuamine. Tetrahedron Lett 1972; 50: 5069-72
9. Yang XW, Zhao J, Cui YX, Liu XH, Ma CM, Hattori M et al. Anti-HIV-1 protease triterpenoid saponins from the seeds of Aesculus chinensis. J Nat Prod 1999; 62: 1510-3
10. Thorell A, Agurell S, Sandberg F, Norin T. Three new alkaloids from the bark of Erythrophleum guineense G. Don syn. E. suaveolens (Guill. & Perr) Brenan. Acta Chem Scan 1968; 22: 2835-44
11. Kitagawa I, Taniyama T, Nagahama Y, Okubo K, Yamauchi F, Yoshikawa M. Saponin and sapogenol. XLII. Structures of acetyl-sayasaponins A1, A2, and A3, astringent partially acetylated bisdesmasides of soyasapogenol A, from American soybean, the seeds of Glycine max Merrill. Chem Pharm Bull 1988; 36: 2819-28