Tertiary Gleason Pattern 5 is a Powerful Predictor of Biochemical Relapse in Patients With Gleason Score 7 Prostatic Adenocarcinoma

Journal of Urology

Volumn 175, Issue 5, 2006, Pages 1695-1699

  Hattab, Eyas M ^a   Koch, Michael O ^a   Eble, John N ^a   Lin, Haiqun ^b   Cheng, Liang ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY   (United States)

Author keywords

adenocarcinoma; neoplasm staging; prognosis; prostate; prostatectomy

Indexed keywords

PROSTATE SPECIFIC ANTIGEN;

ADULT; AGED; ARTICLE; CANCER RELAPSE; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CHEMICAL ANALYSIS; CONTROLLED STUDY; DISEASE COURSE; GLEASON SCORE; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PREDICTION; PREDICTOR VARIABLE; PRIORITY JOURNAL; PROBABILITY; PROGNOSIS; PROSTATE ADENOCARCINOMA; PROSTATE CANCER; PROSTATECTOMY; REGRESSION ANALYSIS; STATISTICAL SIGNIFICANCE;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; HUMANS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; PROSTATE-SPECIFIC ANTIGEN; PROSTATECTOMY; PROSTATIC NEOPLASMS;

EID: 33645977476     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(05)00998-5     Document Type: Article

References (20)

1. Bostwick D.G., Grignon D.J., Hammond M.E., Amin M.B., Cohen M., Crawford D., et al. Prognostic factors in prostate cancer. College of American Pathologists Consensus Statement 1999. Arch Pathol Lab Med 124 (2000) 995
2. Zincke H., Oesterling J.E., Blute M.L., Bergstralh E.J., Myers R.P., and Barrett D.M. Long-term (15 years) results after radical prostatectomy for clinically localized (stage T2c or lower) prostate cancer. J Urol, part 2 152 (1994) 1850
3. Lerner S.E., Blute M.L., Bergstralh E.J., Bostwick D.G., Eickholt J.T., and Zincke H. Analysis of risk factors for progression in patients with pathologically confined prostate cancers after radical retropubic prostatectomy. J Urol 156 (1996) 137
4. Cheng L., Sebo T.J., Slezak J., Pisansky T.M., Bergatrahl E.J., Neumann R.M., et al. Predictors of survival in prostate carcinoma patients treated with salvage prostatectomy after radiation therapy. Cancer 83 (1998) 2164
5. Epstein J.I., Partin A.W., Sauvageot J., and Walsh P.C. Prediction of progression following radical prostatectomy. A multivariate analysis of 721 men with long-term follow-up. Am J Surg Pathol 20 (1996) 286
6. Rasiah K.K., Stricker P.D., Haynes A.M., Delprado W., Turner J.J., Golovsky D., et al. Prognostic significance of Gleason pattern in patients with Gleason score 7 prostate carcinoma. Cancer 98 (2003) 2560
7. Tefilli M.V., Gheiler E.L., Tiguert R., Sakr W., Grignon D.J., Banerjee M., et al. Should Gleason score 7 prostate cancer be considered a unique category?. Urology 53 (1999) 372
8. Epstein J.I., Pound C.R., Partin A.W., and Walsh P.C. Disease progression following radical prostatectomy in men with Gleason score 7 tumor. J Urol 160 (1998) 97
9. Chan T.Y., Partin A.W., Walsh P.C., and Epstein J.I. Prognostic significance of Gleason score 3+4 versus Gleason score 4+3 tumor at radical prostatectomy. Urology 56 (2000) 823
10. Herman C.M., Kattan M.W., Ohori M., Scardino P.T., and Wheeler T.M. Primary Gleason pattern as a predictor of disease progression in Gleason score 7 prostate cancer. a multivariate analysis of 823 men treated with radical prostatectomy. Am J Surg Pathol 25 (2001) 657
11. Sakr W.A., Tefilli M.V., Grignon D.J., Banerjee M., Dey J., Gheiler E.L., et al. Gleason score 7 prostate cancer. a heterogeneous entity? Correlation with pathologic parameters and disease-free survival. Urology 56 (2000) 730
12. Lau W.K., Blute M.L., Bostwick D.G., Weaver A.L., Sebo T.J., and Zincke H. Prognostic factors for survival of patients with pathological Gleason score 7 prostate cancer. differences in outcome between primary Gleason grades 3 and 4. J Urol 166 (2001) 1692
13. Gleason D.F., and Mellinger G.T. Veterans, Administration Cooperative Urological Research Group. Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging. J Urol 111 (1974) 58
14. Mellinger G.T., Gleason D.F., and Bailar III J. The histology and prognosis of prostatic cancer. J Urol 97 (1967) 331
15. Pan C.C., Potter S.R., Partin A.W., and Epstein J.I. The prognostic significance of tertiary Gleason patterns of higher grade in radical prostatectomy specimens. a proposal to modify the Gleason grading system. Am J Surg Pathol 24 (2000) 563
16. Cheng L., Song S.Y., Pretlow T.G., Abdul-Karim F.W., Kung H.J., Dawson D.V., et al. Evidence of independent origin of multiple tumors from patients with prostate cancer. J Natl Cancer Inst 90 (1998) 233
17. Arora R., Koch M.O., Eble J.N., Ulbright T.M., Li L., and Cheng L. Heterogeneity of Gleason grade in multifocal adenocarcinoma of the prostate. Cancer 100 (2004) 2362
18. Cheng L., Koch M.O., Juliar B.E., Daggy J.K., Foster R.S., Bihrle R., et al. The combined percentage of Gleason patterns 4 and 5 is the best predictor of cancer progression after radical prostatectomy. J Clin Oncol 23 (2005) 2911
19. Aihara M., Wheeler T.M., Ohori M., and Scardino P.T. Heterogeneity of prostate cancer in radical prostatectomy specimens. Urology 43 (1994) 60
20. Mosse C.A., Magi-Galluzzi C., Tsuzuki T., and Epstein J.I. The prognostic significance of tertiary Gleason pattern 5 in radical prostatectomy specimens. Am J Surg Pathol 28 (2004) 394