Characterization of porcine β1- and β2- adrenergic receptors in heart, skeletal muscle, and adipose tissue, and the identification of an atypical β-adrenergic binding site

Journal of Animal Science

Volumn 83, Issue 10, 2005, Pages 2339-2348

  Sillence, M N ^a,c   Hooper, J ^a   Zhou, G H ^b   Liu, Q ^b   Munn, K J ^a  

^a CHARLES STURT UNIVERSITY   (Australia)

^b NANJING AGRICULTURAL UNIVERSITY   (China)

^c NONE   (Australia)

Author keywords

Adipose Tissue; Heart; Muscle; Pigs; Adrenergic Receptors

Indexed keywords

SUIDAE; SUS SCROFA;

4 (3 TERT BUTYLAMINO 2 HYDROXYPROPOXY) 2 BENZIMIDAZOLONE; ADRENERGIC RECEPTOR STIMULATING AGENT; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; PROPANOLAMINE DERIVATIVE;

ADIPOSE TISSUE; ANIMAL; ANIMAL DISEASE; ARTICLE; BINDING SITE; CHO CELL; COMPARATIVE STUDY; CRICETULUS; DRUG EFFECT; HAMSTER; HEART MUSCLE; MALE; METABOLISM; PHYSIOLOGY; RADIOASSAY; SKELETAL MUSCLE; SWINE;

ADIPOSE TISSUE; ADRENERGIC AGONISTS; ANIMALS; BINDING SITES; CHO CELLS; CRICETINAE; CRICETULUS; MALE; MUSCLE, SKELETAL; MYOCARDIUM; PROPANOLAMINES; RADIOLIGAND ASSAY; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2; SWINE;

EID: 33645966815     PISSN: 00218812     EISSN: None     Source Type: Journal    
DOI: 10.2527/2005.83102339x     Document Type: Article

References (27)

1. 1-adrenergic receptor gene. J. Anim. Sci. 76:1720-1721.
2. Caron, M. G., and R. J. Lefkowitz. 1993. Catecholamine receptors: structure, function and regulation. Recent Prog. Horm. Res. 48:277-290.
3. Coutinho, L. L., W. G. Bergen, R. A. Merkel, and C. K. Smith. 1992. Quantitative characterization of beta-adrenergic receptor subtypes in porcine adipocytes. Comp. Biochem. Physiol. 101C(3):481-485.
4. 3-adrenergic receptor. Science 245:1118-1121.
5. 2-adrenoceptors induce muscle growth: Methodological development and a study of clenbuterol. Ph.D. Thesis. Central Queensland Univ., Rockhampton, Queensland, Australia.
6. Kaumann, A. J. 1997. Four β-adrenoceptor subtypes in the mammalian heart. Trends Pharmacol. Sci. 18:70-76.
7. 2-adrenergic receptor gene. J. Anim. Sci. 75:2824.
8. 2-adrenergic receptor. J. Anim. Sci. 79:877-883.
9. Liang, W., and S. E. Mills. 2002. Quantitative analysis of β-adrenergic receptor subtypes in pig tissues. J. Anim. Sci. 80:963-970.
10. Liu, C. Y., J. L. Boyer, and S. E. Mills. 1989. Acute effects of beta-adrenergic agonists on porcine adipocyte metabolism in vitro. J. Anim. Sci. 67:2930-2936.
11. 2-adrenergic receptors in E. coli as a new tool for ligand screening. Biotechnology (N.Y.) 7:923-927.
12. 1-antagonists. J. Lipid Res. 29:587-601.
13. McNeel, R. L., and H. J. Mersmann. 1995. β-Adrenergic receptor subtype transcripts in porcine adipose tissue. J. Anim. Sci. 73:1962-1971.
14. 3-adrenergic receptor subtype transcripts in porcine tissues. J. Anim. Sci. 77:611-621.
15. 3-adrenergic receptors in porcine adipocytes. J. Anim. Sci. 74:984-992.
16. Mersmann, H. J. 1998. Overview of the effects of β-adrenergic receptor agonists on animal growth including mechanisms of action. J. Anim. Sci. 76:160-172.
17. Mersmann, H. J. 2002. Beta adrenergic receptor modulation of adipocyte metabolism and growth. J. Anim. Sci. 80(Suppl. 1):E24-E29.
18. Mersmann, H. J., K. Akanabi, A. Shparber, and R. L. McNeel. 1993. Binding of agonists and antagonists to the porcine adipose tissue β-adrenergic receptor(s). Comp. Biochem. Physiol. 106C:725-732.
19. Mersmann, H. J., and R. L. McNeel. 1992. Ligand binding to the porcine adipose tissue β-adrenergic receptor. J. Anim. Sci. 70:787-797.
20. Munson, P. J., and D. Rodbard. 1980. LIGAND: a versatile computerized approach for characterization of ligand-binding systems. Anal. Biochem. 107:220-239.
21. Prengle, A. W., K. G. Lindner, T. Anhaupl, J. Vogt, and K. G. Lurie. 1996. Regulation of right atrial β-adrenoceptors after cardiopulmonary resuscitation in pigs. Resuscitation 31:271-278.
22. 125I]I-iodocyanopindolol binding sites in rat soleus muscle. Br. J. Pharmacol. 109:344-352.
23. Sato, S., N. Sato, R. J. Kudej, M. Uiechi, K. K. Asai, Y.-T. Shen, Y. Ishikawa, S. F. Vatner, and D. E. Vatner. 1997. β-Adrenergic receptor signalling in stunned myocardium of conscious pigs. J. Mol. Cell. Cardiol. 29:1387-1400.
24. Sillence, M. N., and M. L. Mathews. 1994. Classical and atypical binding sites for β-adrenoceptor ligands and activation of adenylyl cyclase in bovine skeletal muscle and adipose tissue membranes. Br. J. Pharmacol. 111:866-872.
25. 3-adrenoceptors compared in brown adipose tissue and in skeletal muscle membranes. Br. J. Pharmacol. 190:1157-1163.
26. 2-adrenoceptors in bovine skeletal muscle, and the effect of these compounds on urinary nitrogen excretion in female rats. Arch. Pharmacol. 344:442-448.
27. Williams, R. S., M. G. Caron, and D. Keifer. 1984. Skeletal muscle β-adrenergic receptors: variations due to fibre type and training. Am. J. Physiol. 246:E160-E167.