Cardiac efficiency and oxygen consumption measured with 11C-acetate PET after long-term cardiac resynchronization therapy

Journal of Nuclear Medicine

Volumn 47, Issue 3, 2006, Pages 378-383

  Lindner, Oliver ^a   Sörensen, Jens ^b   Vogt, Jürgen ^a   Fricke, Eva ^a   Baller, Detlev ^a   Horstkotte, Dieter ^a   Burchert, Wolfgang ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Bundle branch block; Cardiac output; Heart failure; Pacing

Indexed keywords

ACETIC ACID C 11; AMIODARONE; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; NITRIC ACID DERIVATIVE; ACETIC ACID DERIVATIVE; CARBON; CARBON 11 ACETATE; CARBON-11 ACETATE; DIAGNOSTIC AGENT; RADIOPHARMACEUTICAL AGENT;

ADULT; AGED; ARTICLE; CARDIAC RESYNCHRONIZATION THERAPY; CARDIOMYOPATHY; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION COEFFICIENT; DISEASE SEVERITY; DRUG CLEARANCE; FEMALE; HEART FAILURE; HEART HEMODYNAMICS; HEART LEFT BUNDLE BRANCH BLOCK; HEART MUSCLE METABOLISM; HEART PERFORMANCE; HEART STROKE VOLUME; HUMAN; IDIOPATHIC DISEASE; MALE; OUTCOME ASSESSMENT; OXYGEN CONSUMPTION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; TREATMENT DURATION; ADOLESCENT; CLINICAL TRIAL; CONGESTIVE HEART FAILURE; CONTROLLED CLINICAL TRIAL; CONVALESCENCE; HEART BUNDLE BRANCH BLOCK; HEART OUTPUT; HEART PACING; LONGITUDINAL STUDY; METHODOLOGY; MIDDLE AGED; TREATMENT OUTCOME;

ACETATES; ADOLESCENT; ADULT; AGED; BUNDLE-BRANCH BLOCK; CARBON; CARDIAC OUTPUT; CARDIAC PACING, ARTIFICIAL; FEMALE; HEART FAILURE, CONGESTIVE; HUMANS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; OXYGEN CONSUMPTION; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; RECOVERY OF FUNCTION; TREATMENT OUTCOME;

EID: 33645964338     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Hochleitner M, Hortnagl H, Fridrich L, Gschnitzer F. Long-term efficacy of physiologic dual-chamber pacing in the treatment of end-stage idiopathic dilated cardiomyopathy. Am J Cardiol. 1992;70:1320-1325.
2. Abraham WT, Hayes DL. Cardiac resynchronization therapy for heart failure. Circulation. 2003;108:2596-2603.
3. Abraham WT, Fisher WG, Smith AL, et al. Cardiac resynchronization in chronic heart failure. N Engl J Med. 2002;346:1845-1853.
4. Cazeau S, Leclercq C, Lavergne T, et al. Effects of multisite biventricular pacing in patients with heart failure and intraventricular conduction delay. N Engl J Med. 2001;344:873-880.
5. Linde C, Leclercq C, Rex S, et al. Long-term benefits of biventricular pacing in congestive heart failure: results from the multisite stimulation in cardiomyopathy (MUSTIC) study. J Am Coll Cardiol. 2002;40:111-118.
6. Cleland JG, Daubert JC, Erdmann E, et al. The effect of cardiac resynchronization on morbidity and mortality in heart failure. N Engl J Med. 2005;352:1539-1549.
7. Ezekowitz JA, Armstrong PW, McAlister FA. Implantable cardioverter defibrillators in primary and secondary prevention: a systematic review of randomized, controlled trials. Ann Intern Med. 2003;138:445-452.
8. Gregoratos G, Abrams J, Epstein AE, et al. ACC/AHA/NASPE 2002 guideline update for implantation of cardiac pacemakers and antiarrhythmia devices: summary article - a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/NASPE Committee to Update the 1998 Pacemaker Guidelines). Circulation. 2002;106:2145-2161.
9. Lindner O, Vogt J, Kammeier A, et al. Effect of cardiac resynchronization therapy on global and regional oxygen consumption and myocardial blood flow in patients with non-ischaemic and ischaemic cardiomyopathy. Eur Heart J. 2005;26:70-76.
10. Knaapen P, van Campen LM, de Cock CC, et al. Effects of cardiac resynchronization therapy on myocardial perfusion reserve. Circulation. 2004;110:646-651.
11. Nowak B, Sinha AM, Schaefer WM, et al. Cardiac resynchronization therapy homogenizes myocardial glucose metabolism and perfusion in dilated cardiomyopathy and left bundle branch block. J Am Coll Cardiol. 2003;41:1523-1528.
12. Nelson GS, Berger RD, Fetics BJ, et al. Left ventricular or biventricular pacing improves cardiac function at diminished energy cost in patients with dilated cardiomyopathy and left bundle-branch block. Circulation. 2000;102:3053-3059.
13. Ukkonen H, Beanlands RS, Burwash IG, et al. Effect of cardiac resynchronization on myocardial efficiency and regional oxidative metabolism. Circulation. 2003;107:28-31.
14. Sundell J, Engblom E, Koistinen J, et al. The effects of cardiac resynchronization therapy on left ventricular function, myocardial energetics, and metabolic reserve in patients with dilated cardiomyopathy and heart failure. J Am Coll Cardiol. 2004;43:1027-1033.
15. Auricchio A, Stellbrink C, Butter C, et al. Clinical efficacy of cardiac resynchronization therapy using left ventricular pacing in heart failure patients stratified by severity of ventricular conduction delay. J Am Coll Cardiol. 2003;42:2109-2116.
16. Stellbrink C, Auricchio A, Butter C, et al. Pacing therapies in congestive heart failure II study. Am J Cardiol. 2000;86:138K-143K.
17. Vogt J, Krahnefeld O, Lamp B, et al. Electrocardiographic remodeling in patients paced for heart failure. Am J Cardiol. 2000;86:152K-156K.
18. 11C]Acetate as a quantitative perfusion tracer in myocardial PET. J Nucl Med. 2001;42:1174-1182.
19. 11C-acetate and positron emission tomography: threshold criteria of reversible dysfunction. Circulation. 1997;95:1417-1424.
20. 11C-acetate PET verified in a pig model. J Nucl Med. 2003;44:1176-1183.
21. Stellbrink C, Auricchio A, Diem B, et al. Potential benefit of biventricular pacing in patients with congestive heart failure and ventricular tachyarrhythmia. Am J Cardiol. 1999;83:143D-150D.
22. St John Sutton MG, Plappert T, Abraham WT, et al. Effect of cardiac resynchronization therapy on left ventricular size and function in chronic heart failure. Circulation. 2003;107:1985-1990.
23. 11C-acetate. In: Schwaiger M, ed. Cardiac Positron Emission Tomography. Boston, MA: Kluwer Academic Publishers; 1995:297-309.
24. Henry PD, Eckberg D, Gault JH, Ross JJ. Depressed inotropic state and reduced myocardial oxygen consumption in the human heart. Am J Cardiol. 1973;31:300-306.
25. Pasternac A, Noble J, Streulens Y, et al. Pathophysiology of chest pain in patients with cardiomyopathies and normal coronary arteries. Circulation. 1982;65:778-789.
26. Beanlands RS, Bach DS, Raylman R, et al. Acute effects of dobutamine on myocardial oxygen consumption and cardiac efficiency measured using carbon-11 acetate kinetics in patients with dilated cardiomyopathy. J Am Coll Cardiol. 1993;22:1389-1398.
27. Baller D, Schenk H, Strauer BE, Hellige G. Comparison of myocardial oxygen consumption indices in man. Clin Cardiol. 1980;3:116-122.
28. Spragg DD, Leclercq C, Loghmani M, et al. Regional alterations in protein expression in the dyssynchronous failing heart. Circulation. 2003;108:929-932.
29. Auricchio A, Salo RW. Acute hemodynamic improvement by pacing in patients with severe congestive heart failure. Pacing Clin Electrophysiol. 1997;20:313-324.