Anti-hyperglycaemic and anti-dyslipidaemic effect of dietary supplement of white Ocimum Sanctum Linnean before and after STZ-induced diabetes mellitus

International Journal of Diabetes and Metabolism

Volumn 13, Issue 1, 2005, Pages 18-23

  Suanarunsawat, Thamolwan ^a   Songsak, Thanapat ^a  

^a RANGSIT UNIVERSITY   (Thailand)

Author keywords

Diabetes mellitus; Ocimum sanctum Linnean; Serum lipid

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CREATININE; OCIMUM SANCTUM EXTRACT;

ANIMAL MODEL; ARTICLE; BASIL; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DATA ANALYSIS; DIABETES MELLITUS; DIET SUPPLEMENTATION; DIET THERAPY; DRUG EFFECT; DRUG SYNTHESIS; GLOMERULUS FILTRATION; GLUCOSE BLOOD LEVEL; LIVER FUNCTION; MEDICINAL PLANT; NONHUMAN; OCIMUM SANCTUM LINNEAN; RAT; STATISTICAL ANALYSIS; STREPTOZOCIN DIABETES; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 33645962485     PISSN: 16067754     EISSN: None     Source Type: Journal    
DOI: 10.1159/000497569     Document Type: Article

References (18)

1. Kacsoh B. The endocrine pancreas. In: Endocrine Physiology. Kacsoh B.(editor). McGraw-Hill, New York; 2000: pp 189-250.
2. American Diabetes Association. Clinical practice recommendation. Diabetes Care. 1997; 20 (suppl.1): S1-S70.
3. Baynes JW. Role of oxidative stress in development of complications in diabetes. Diabetes 1991; 40: 405-412.
4. Barnett A. Management of lipids in patients with diabetes. Diabetes Obes Metab 2003; 5 (suppl 1): S3-S9.
5. Neil A. Diabetes and cardiovascular disease. Diabetes Obes Metab 2003; 5 (suppl. 1): S11-S18.
6. Bunjob M, Chaiyalart S. The study of hypoglycemic effect of Thai herbals. The Ministry of Public Health of Thailand, 1997.
7. Chattopadhyay RR. A comparative evaluation of some blood sugar lowering agents of plant origin. J Ethnopharmacol 1999; 6: 367-372.
8. Rai V, Iyer U, Mani UV. Effect of Tulsi (Ocimum sanctum) leave powder supplementation on blood sugar levels, serum lipids and tissue lipids in diabetic rats. Plant Foods Human Nutrition 1997; 50: 9-16.
9. Janabai G, Suganthi B, Meera G. Effect of Tulsi (Ocimum sanctum) on diabetes mellitus. Ind J Nutr Diet 1987; 24: 337-341.
10. Sarkar A, Lavania SC, Pandey DN, Pant MC. Changes in the blood lipid profile after administration of Ocimum sanctum (Tulsi) leaves in the normal albino rabbits. Indian J Physiol Pharmacol 1994; 38: 311-312.
11. Pushpangadan P, Sobti SN. Medical properties of Ocimum (Tulsi) species and some recent investigations of their efficacy. Indian Drugs 1997; 14: 207-208.
12. Vats V, Grover JK, Rathi SS. Evaluation of anti-hyperglycemic and hypoglycemic effect of Trigonella foernum-graecum Linnean Ocimum sanctum Linnean and Pterocarpus marsupium Linnean in normal and alloxanized diabetic rats. J Ethnopharmacol 2002; 79: 95-100.
13. Vats V, Yadav SP, Grover JK. Ethanol extract of Ocimum sanctum leaves partially attenuates streptozotocin-induced alterations in glycogen content and carbohydrate metabolism in rats. J Ethnopharmacol 2004; 90: 155-160.
14. Bhattacharya SK, Satyan KS, Chakrabarti A. Effect of Trasina, an Ayurvedic herbal formulation, on pancreatic islet superoxide dismutase activity in hyperglycemic rats. Indian J Exp Biol 1997; 35: 297-299.
15. Abou-Seif MA, Youssef AA. Evaluation of some biochemical changes in diabetic patients. Clin Chim Acta 2004; 346: 161-170.
16. Nair AGR, Gunasegaran R. Chemical investigation of certain South Indian plants. Ind J Chem 1982; 21: 979.
17. Dey BB, Chaudhuri MA. Essential oil of Ocimum sanctum and its antimicrobial activity. Indian Perfum 1984; 28: 82-86.
18. Reddy AC, Lokesh BR. Effect of curcumin and eugenol on iron-induced hepatic toxicity in rats. Toxicology 1996; 107: 39-45.