Acetylornithine transcarbamylase: A novel enzyme in arginine biosynthesis

Journal of Bacteriology

Volumn 188, Issue 8, 2006, Pages 2974-2982

  Morizono, Hiroki ^a   Cabrera Luque, Juan ^a   Shi, Dashuang ^a   Gallegos, Rene ^b   Yamaguchi, Saori ^c   Yu, Xiaolin ^a   Allewell, Norma M ^c   Malamy, Michael H ^b   Tuchman, Mendel ^a  

^a CHILDREN S RESEARCH INSTITUTE   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLORNITHINE TRANSCARBAMYLASE; ARGININE; BACTERIAL DNA; CARBAMOYL PHOSPHATE; CARBAMOYLTRANSFERASE; CITRULLINE; ENZYME INHIBITOR; N ACETYLCITRULLINE; N ACETYLORNITHINE; NALPHA ACETYL N DELTA PHOSPHONOACETYLORNITHINE; ORNITHINE; UNCLASSIFIED DRUG;

AMINO ACID SYNTHESIS; ARGF GENE; ARTICLE; BACTERIAL GENE; BACTERIAL GENOME; BACTEROIDETES; CATALYSIS; CYTOPHAGA; DNA SEQUENCE; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME KINETICS; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENE OVEREXPRESSION; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; UREA CYCLE; XANTHOMONADACEAE; XANTHOMONAS CAMPESTRIS;

ARGININE; BACTEROIDETES; CARBAMYL PHOSPHATE; CARBOXYL AND CARBAMOYL TRANSFERASES; CLONING, MOLECULAR; CYTOPHAGA; ENZYME INHIBITORS; ESCHERICHIA COLI; GENE EXPRESSION; GENOME, BACTERIAL; MASS SPECTROMETRY; MOLECULAR STRUCTURE; ORNITHINE; XANTHOMONAS CAMPESTRIS;

BACTERIA (MICROORGANISMS); BACTEROIDETES; CYTOPHAGA; ESCHERICHIA; ESCHERICHIA COLI; XANTHOMONADACEAE; XANTHOMONAS CAMPESTRIS;

EID: 33645958863     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.188.8.2974-2982.2006     Document Type: Article

References (30)

1. Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
2. Caldovic, L., H. Morizono, X. Yu, M. Thompson, D. Shi, R. Gallegos, N. M. Allewell, M. H. Malamy, and M. Tuchman. 2002. Identification, cloning and expression of the mouse N-acerylglutamate synthase gene. Biochem. J. 364:825-831.
3. Eisen, J. A., K. E. Nelson, I. T. Paulsen, J. F. Heidelberg, M. Wu, R. J. Dodson, R. Deboy, M. L. Gwinn, W. C. Nelson, D. H. Haft, E. K. Hickey, J. D. Peterson, A. S. Durkin, J. L. Kolonay, F. Yang, I. Holt, L. A. Umayam, T. Mason, M. Brenner, T. P. Shea, D. Parksey, W. C. Nierman, T. V. Feldblyum, C. L. Hansen, M. B. Craven, D. Radune, J. Vamathevan, H. Khouri, O. White, T. M. Gruber, K. A. Ketchum, J. C. Venter, H. Tettelin, D. A. Bryant, and C. M. Fraser. 2002. The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium. Proc. Natl. Acad. Sci. USA 99:9509-9514.
4. Fiske, C. H., and Y. Subbarow. 1925. The colorimetic determination of phosphorus. J. Biol. Chem. 66:375-400.
5. Genetics Computer Group. Wisconsin Package version 10.2. Genetics Computer Group, Madison, Wis.
6. Javid-Majd, F., and J. S. Blanchard. 2000. Mechanistic analysis of the argE-encoded N-acetylornithine deacetylase. Biochemistry 39:1285-1293.
7. Labedan, B., A. Boyen, M. Baetens, D. Charlier, P. Chen, R. Cunin, V. Durbeco, N. Glansdorff, G. Hervé, C. Legrain, Z. Liang, C. Purcarea, M. Roovers, R. Sanchez, T. L. Toong, M. Van de Casteele, F. van Vliet, Y. Xu, and Y. F. Zhang. 1999. The evolutionary history of carbamoyltransferases: a complex set of paralogous genes was already present in the last universal common ancestor. J. Mol. Evol. 49:461-473.
8. Lee, Y., B. O. Jun, S. G. Kim, and Y. M. Kwon. 1998. Purification of ornithine carbamoyltransferase from kidney bean (Phaseolus vulgaris L.) leaves and comparison of the properties of the enzyme from canavanine-containing and -deficient plants. Planta 205:375-379.
9. Legrain, C., V. Stalon, J. P. Noullez, A. Mercenier, J. P. Simon, K. Broman, and J. M. Wiame. 1977. Structure and function of ornithine carbamoyltransferases. Eur. J. Biochem. 80:401-409.
10. Morizono, H., M. Tuchman, B. S. Rajagopal, M. T. McCann, C. D. Listrom, X. Yuan, D. Venugopal, G. Barany, and N. M. Allewell. 1997. Expression, purification and kinetic characterization of wild-type human ornithine transcarbamylase and a recurrent mutant that produces 'late onset' hyperammonaemia. Biochem. J. 322:625-631.
11. Naumoff, D. G., Y. Xu, N. Glansdorff, and B. Labedan. 2004. Retrieving sequences of enzymes experimentally characterized but erroneously annotated: the case of the putrescine carbamoyltransferase. BMC Genomics 5:52.
12. Pastra-Landis, S. C., J. Foote, and E. R. Kantrowitz. 1981. An improved colorimetric assay for aspartate and ornithine transcarbamylases. Anal. Biochem. 118:358-363.
13. Rice, P., I. Longden, and A Bleasby. 2000. EMBOSS: the European Molecular Biology Open Software Suite. Trends Genet. 16:276-277.
14. Roovers, M., C. Hethke, C. Legrain, M. Thomm, and N. Glansdorff. 1997. Isolation of the gene encoding Pyrococcus furiosus ornithine carbamoyltransferase and study of its expression profile in vivo and in vitro. Eur. J. Biochem. 247:1038-1045.
15. Sainz, G., C. Tricot, M. F. Foray, D. Marion, O. Dideberg, and V. Stalon. 1998. Kinetic studies of allosteric catabolic ornithine carbamoyltransferase from Pseudomonas aeruginosa. Eur. J. Biochem. 251:528-533.
16. Shi, D., R. Gallegos, J. DePonte III, H. Morizono, X. Yu, N. M. Allewell, M. Malamy, and M. Tuchman. 2002. Crystal structure of a transcarbamylase-like protein from the anaerobic bacterium Bacteroides fragilis at 2.0 A resolution. J. Mol. Biol. 320:899-908.
17. Shi, D., H. Morizono, Y. Ha, M. Aoyagi, M. Tuchman, and N. M. Allewell. 1998. 1.85- Å resolution crystal structure of human ornithine transcarbamoylase complexed with N-phosphonacetyl-L-ornithine. Catalytic mechanism and correlation with inherited deficiency. J. Biol. Chem. 273:34247-34254.
18. Shi, D., H. Morizono, X. Yu, L. Roth, L. Caldovic, N. M. Allewell, M. H. Malamy, and M. Tuchman. 2005. Crystal structure of N-acetylornithine transcarbamylase from Xanthomonas campestris: a novel enzyme in a new arginine biosynthetic pathway found in several eubacteria. J. Biol. Chem. 280:14366-14369.
19. Shi, D., H. Morizono, X. Yu, L. Tong, N. M. Allewell, and M. Tuchman. 2001. Human ornithine transcarbamylase: crystallographic insights into substrate recognition and conformational changes. Biochem. J. 354:501-509.
20. Spector, L., M. E. Jones, and F. Lipmann. 1957. Carbamyl phosphate. Methods Enzymol. 3:653-655.
21. Stalon, V., F. Ramos, A. Pierard, and J. M. Wiame. 1967. The occurrence of a catabolic and an anabolic ornithine carbamoyltransferase in Pseudomonas. Biochim. Biophys. Acta 139:91-97.
22. Staskawicz, B. J., and N. J. Panopoulos. 1980. Phaseolotoxin transport in Escherichia coli and Salmonella typhimurium via the oligopeptide permease. J. Bacteriol. 142:474-479.
23. Strandholm, J. J., N. R. Buist, N. G. Kennaway, and H. T. Curtis. 1971. Excretion of N-acetylcitrulline in citrullinaemia. Biochim. Biophys. Acta 244:214-216.
24. Tigier, H., and S. Grisolia. 1965. Induction of Carbamyl-P specific oxamate transcarbamylase by parabanic acid in a Streptococcus. Biochem. Biophys. Res. Commun. 19:209-214.
25. Tricot, C., J. L. De Coen, P. Momin, P. Falmagne, and V. Stalon. 1989. Evolutionary relationships among bacterial carbamoyltransferases. J. Gen. Microbiol. 135:2453-2464.
26. Tuchman, M., H. Morizono, O. Reish, X. Yuan, and N. M. Allewell. 1995. The molecular basis of ornithine transcarbamylase deficiency: modelling the human enzyme and the effects of mutations. J. Med. Genet. 32:680-688.
27. Venter, J. C., K. Remington, J. F. Heidelberg, A. L. Halpern, D. Rusch, J. A. Eisen, D. Wu, I. Paulsen, K. E. Nelson, W. Nelson, D. E. Fouts, S. Levy, A. H. Knap, M. W. Lomas, K. Nealson, O. White, J. Peterson, J. Hoffman, R. Parsons, H. Baden-Tillson, C. Pfannkoch, Y. H. Rogers, and H. O. Smith. 2004. Environmental genome shotgun sequencing of the Sargasso Sea. Science 304:66-74.
28. Vogel, H. J., and W. L. McLellan. 1971. Acetylornithinase (Escherichia coli). Methods Enzymol. 17A:265-269.
29. Wargnies, B., N. Lauwers, and V. Stalon. 1979. Structure and properties of the putrescine carbamoyltransferase of Streptococcus faecalis. Eur. J. Biochem. 101:143-152.
30. Wheeler, D. L., D. M. Church, S. Federhen, A. E. Lash, T. L. Madden, J. U. Pontius, G. D. Schuler, L. M. Schriml, E. Sequeira, T. A. Tatusova, and L. Wagner. 2003. Database resources of the National Center for Biotechnology. Nucleic Acids Res. 31:28-33.