Lipoblastic nerve sheath tumors: Report of a distinctive variant of neural soft tissue neoplasm with adipocytic differentiation

American Journal of Surgical Pathology

Volumn 30, Issue 3, 2006, Pages 337-344

  Plaza, Jose Antonio ^a   Wakely, Paul E ^a   Suster, Saul ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

Author keywords

Aberrant differentiation; Nerve sheath neoplasms; Signet ring cells; Signet ring lipoblasts

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CD34 ANTIGEN; CD56 ANTIGEN; CYTOKERATIN; DESMIN; EPITHELIAL MEMBRANE ANTIGEN; FAT DROPLET; MUCIN; PROTEIN BCL 2; PROTEIN S 100; SMOOTH MUSCLE ACTIN; VIMENTIN;

ADIPOCYTE; ADULT; ARTICLE; CELL DIFFERENTIATION; CELL ULTRASTRUCTURE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INGUINAL REGION; LIPOBLAST; MALE; NERVE SHEATH TUMOR; NEURILEMOMA; NEUROFIBROMA; NUCLEAR MAGNETIC RESONANCE IMAGING; RETROPERITONEUM; SHOULDER; SIGNET RING CARCINOMA; SOFT TISSUE TUMOR; SPINDLE CELL CARCINOMA; THIGH; ADENOCARCINOMA; ADIPOSE TISSUE; METABOLISM; MIDDLE AGED; PATHOLOGY; TRANSMISSION ELECTRON MICROSCOPY;

ADENOCARCINOMA; ADIPOSE TISSUE; ADULT; CARCINOMA, SIGNET RING CELL; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; MIDDLE AGED; NERVE SHEATH NEOPLASMS; SOFT TISSUE NEOPLASMS;

EID: 33645958575     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.pas.0000194297.81721.1c     Document Type: Article

References (42)

1. Alguacil-Garcia A. Artifactual changes mimicking signet-ring cell carcinoma in transurethral prostatectomy specimens. Am J Surg Pathol. 1986;10:795-800.
2. Al-Talib RK, Theaker JM. Signet-ring cell melanoma: light microscopic, immunohistochemical and ultrastructural features. Histopathology. 1991;18:572-575.
3. Arista-Nasr J, Romero-Lagarza P, Pichrado-Bahena R. Artifactual signet-ring like cells in endoscopic biopsy of gastric lymphoma. Arch Pathol Lab Med. 1997;121:623-625.
4. Banerjee SS, Harris M. Morphological and immunophenotypic variations in malignant melanoma. Histopathology. 2000;36:387-402.
5. Brooks JJ, Wells G, Yeh I, et al. Bizarre epithelioid lipoleoimyoma of the uterus. Int J Gynecol Pathol. 1992;11:144-149.
6. Carney JA. Psammomatous melanotic schwannoma: a distinctive, heritable tumor with special associations, including cardiac myxoma and the Cushing syndrome. Am J Surg Pathol. 1990;14:206-222.
7. Dei Tos AP, Mentzel T, Newman PL, et al. Spindle cell liposarcoma, a hitherto unrecognized variant of liposarcoma: analysis of six cases. Am J Surg Pathol. 1994;18:913-921.
8. Demetrick DJ, Kneasfey PD, Hwang W-S. Signet-ring chondrosarcoma: a new morphologic entity. Hum Pathol. 1991;22:1175-1179.
9. Eyden BP, Banerjee SS. Multiple myeloma showing signet-ring cell change. Histopathology. 1990;7:170-172.
10. Folpe AL, Weiss SW. Lipoleiomyosarcoma (well-differentiated liposarcoma with leiomyosarcomatous differentiation): a clinicopathologic study of nine cases including one with dedifferentiation. Am J Surg Pathol. 2002;26:742-749.
11. Hanna W, Kahn HJ, From L. Signet ring lymphoma of the skin: ultrastructural and immunohistochemical features. J Am Acad Dermatol. 1986;2:344-350.
12. Heffner DK, Gnepp DR. Sinonasal fibrosarcomas, malignant schwannomas, and 'Triton' tumors: a clinicopathologic study of 67 cases. Cancer. 1992;70:1089-1101.
13. Henricks WH, Chu YC, Goldblum JR, et al. Dedifferentiated liposarcoma: a clinicopathological analysis of 155 cases with a proposal for an expanded definition of dedifferentiation. Am J Surg Pathol. 1997;21:271-281.
14. Humphrey CD, Pittman FE. A simple methylene blue-azure II-basic fuchsin stain for epoxy-embedded tissue sections. Stain Technol. 1974;49:9-14.
15. Jaffer S, Woodruff JM. Cytology of melanotic schwannoma in a fine needle aspirate and pleural fluid: a case report. Acta Cytol. 2000;44:1095-1100.
16. Kasantikul V, Brown WJ, Netsky MG. Mesenchymal differentiation in trigeminal neurilemmoma. Cancer. 1982;50:1568-1571.
17. Kilpatrick SE, Doyon J, Choong PF, et al. The clinicopathologic spectrum of myxoid and round cell liposarcoma: a study of 95 cases. Cancer. 1996;77:1450-1458.
18. Kim H, Dorfman RF, Rappaport H. Signet-ring cell lymphoma: a rare morphologic and functional expression of nodular (follicular) lymphoma. Am J Surg Pathol. 1978;2:119-132.
19. Klima M, Smith M, Spjut HJ, et al. Malignant mesenchymoma: case report with electron microscopic study. Cancer. 1975;36:1086-1094.
20. Lattes R, Bigotti G. Lipoblastic meningioma: 'vacuolated meningioma.' Hum Pathol. 1991;22:164-171.
21. McCormick D, Mentzel T, Beham A, et al. Dedifferentiated liposarcoma: clinicopathologic analysis of 32 cases suggesting a better prognostic subgroup among pleomorphic sarcomas. Am J Surg Pathol. 1994;18:1213-1223.
22. Moran CA, Suster S, Abbondanzo SL. Cutaneous B-cell lymphoma with signet ring-cell morphology: a clinicopathologic and immunohistochemical study of three cases. Am J Dermatopathol. 2001;23:181-184.
23. Morphopoulos GD, Banerjee SS, Ali HH, et al. Malignant peripheral nerve sheath tumour with vascular differentiation: a report of four cases. Histopathology. 1996;28:401-410.
24. Nascimento AF, Fletcher CDM. Spindle cell liposarcoma/atypical lipomatous tumor: a clinicopathologic study of 120 cases. Mod Pathol. 2005;18(suppl1):19A.
25. Navas-Palacios JJ, Valdes MD, Lahuerta-Palacios JJ. Signet-ring cell lymphoma: ultrastructural and immunohistochemical features of three varieties. Cancer. 1983;52:1613-1623.
26. Ordoñez NG, Sahin AA. CA 125 production in desmoplastic small round cell tumor: report of a case with elevated serum levels and prominent signet ring morphology. Hum Pathol. 1998;29:294-299.
27. Perez-Montiel DM, Plaza JA, Wakely P, et al. Metastases to soft tissue sites: review of 86 cases over a 30-year period. Mod Pathol. 2003;16:19A.
28. Raju U, Ma CK, Shaw A. Signet ring variant of lobular carcinoma of the breast: a clinicopathologic and immunohistochemical study. Mod Pathol. 1993;6:516-520.
29. Ramnani D, Lindberg G, Gokaslan T, et al. Signet-ring cell variant of small lymphocytic lymphoma with a prominent sinusoidal pattern. Ann Diagn Pathol. 1999;4:220-226.
30. Scheithauer BW, Woodruff JM, Erlandson RA. Tumors of the Peripheral Nerve System, fascicle 24, series 3. Washington, DC: Armed Forces Institute of Pathology, 1999:156-170.
31. Sheibani K, Battifora H. Signet-ring cell melanoma: a rare morphologic variant of malignant melanoma. Am J Surg Pathol. 1988;12:28-34.
32. Smith TA, Easley KA, Goldblum JR. Myxoid/round cell liposarcoma of the extremities: a clinicopathologic study of 29 cases with particular attention to extent of round cell liposarcoma. Am J Surg Pathol. 1996;2:171-180.
33. Suster S, Fletcher CDM. Gastrointestinal stromal tumors with prominent signet-ring cell features. Mod Pathol. 1996;9:609-613.
34. Suster S, Wong T-Y, Moran CA. Sarcomas with combined features of liposarcoma and leiomyosarcoma: study of 2 cases of an unusual soft tissue tumor showing dual lineage differentiation. Am J Surg Pathol. 1993;17:905-911.
35. Tallini G, Erlandson RA, Brennan MF, et al. Divergent myosarcomatous differentiation in retroperitoneal liposarcoma. Am J Surg Pathol. 1993;17:546-556.
36. Torenbeek R, Koot RA, Blomjous CE, et al. Primary signet-ring cell carcinoma of the urinary bladder. Histopathology. 1996;28:33-40.
37. Torbenson M, Dhir R, Nangia A, et al. Prostatic carcinoma with signet-ring cells: a clinicopathologic and immunohistochemical analysis of 12 cases, with review of the literature. Mod Pathol. 1998;11:552-559.
38. Van Dorpe J, Sciot R, Samson I, et al. Primary osteorhabdomyosarcoma (malignant mesenchymoma) of bone: a case report and review of the literature. Mod Pathol. 1997;10:1047-1053.
39. Van Veen S, Kluin PM, de Kezier RJ, et al. Granulocytic sarcoma (chloroma): presentation of an unusual case. Am J Clin Pathol. 1991;95:567-571.
40. Weiss LM, Wood GS, Dorfman RF. T-cell signet ring-cell lymphoma: a histologic, ultrastructural and immunohistochemical study of two cases. Am J Surg Pathol. 1985;9:273-280.
41. Woodruff JM, Chernik NL, Smith MC, et al. Peripheral nerve tumors with rhabdomyosarcomatous differentiation (malignant 'Triton' tumors). Cancer. 1973;32:426-439.
42. Yokota T, Kunii Y, Teshima S, et al. Signet-ring cell carcinoma of the stomach: a clinicopathological comparison with the other histological types. Tohoku J Exp Med. 1998;186:121-130.