Multiplex STR and mitochondrial DNA testing for paraffin embedded specimen of healthy and malignant tissue: Interpretation issues

International Congress Series

Volumn 1288, Issue , 2006, Pages 648-650

  Lu, C ^a,b   Budimlija, Z ^b,c   Popiolek, D ^c   Illei, P ^c   West, B ^c   Fogt, F ^d   Wei, J J ^c   Prinz, M ^b  

^a JOHN JAY COLLEGE OF CRIMINAL JUSTICE   (United States)

^b Department of Pathology ^*  (United States)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Allelic instability; Human identification; Loss of heterozygosity; Malignant tumors; mtDNA; STR

Indexed keywords

EID: 33645937003     PISSN: 05315131     EISSN: None     Source Type: Book Series    
DOI: 10.1016/j.ics.2005.10.010     Document Type: Article

References (4)

1. Popiolek D.A., et al. Multiplex DNA short tandem repeat analysis: a useful method for determining the provenance of minute fragments of formalin-fixed, paraffin-embedded tissue. Am. J. Clin. Pathol. 120 (2003) 746-751
2. Vauhkonen H., et al. Evaluation of gastrointestinal cancer tissues as a source for forensic investigations by using STRs. Forensic Sci. Int. 139 (2004) 159-167
3. Poetsch M., et al. Evaluation of allelic alterations in short tandem repeats in different kinds of solid tumors-possible pitfalls in forensic casework. Forensic Sci. Int. 145 (2004) 1-6
4. Calloway C.D., et al. The frequency of heteroplasmy in the HVII region of mtDNA differs across tissue types and increases with age. Am. J. Hum. Genet. 66 (2000) 1384-1397