Investigation of the factors affecting catabolism of antibodies raised against a vaccine candidate based on the conserved region of the M-protein

International Congress Series

Volumn 1289, Issue , 2006, Pages 336-339

  Pandey, Manisha ^a   Good, Michael F ^a,b   Batzloff, Michael R ^a,b  

^a ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^b The Cooperative Research Centre for Vaccine Technology   (Australia)

Author keywords

Antibody catabolism; Immunoglobulin aggregation; Passive transfer; Vaccine

Indexed keywords

EID: 33645934234     PISSN: 05315131     EISSN: None     Source Type: Book Series    
DOI: 10.1016/j.ics.2005.11.091     Document Type: Article

References (7)

1. Hayman W.A., et al. Mapping the minimal murine T-cell and B cell epitopes within a peptide vaccine candidate from the conserved region of the M-protein of group A streptococcus. Int. Immunol. 9 11 (1997) 1723-1733
2. Batzloff M.R., et al. Protection against group A streptococcus by immunisation with J8-diptheria toxoid: contribution of J8- and diphtheria toxoid-specific antibodies to protection. J. Inf. Dis. 187 (2003) 1598-1608
3. Brandt E.R., et al. Opsonic human antibodies from an endemic population specific for a conserved epitope on the M protein of group A streptococci. Immunol 89 (1996) 331-337
4. - induced, noncovalent self-aggregation upon storage at room temperature. Free Radic. Biol. Med. 20 3 (1996) 263-270
5. Hanson U.B. Aggregation of human immunogloblin G upon freezing. Acta Chem. Scand. 22 (1968) 483-489
6. Lobatto S., et al. Clearance of soluble aggregates of human immunoglobulin G in healthy volunteers and chimpanzees. Clin. Exp. Immunol. 69 1 (1987) 133-141
7. Leslie R.G.Q. Critical events in the irreversible uptake of soluble immune complexes by macrophages. Immunol. Lett. 11 (1985) 153-158