Molecular mimicry, autoimmunity and infection in the pathogenesis of rheumatic fever

International Congress Series

Volumn 1289, Issue , 2006, Pages 14-19

  Cunningham, Madeleine W ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

Acute rheumatic fever; Molecular mimicry; Pathogenic mechanisms; Rheumatic heart disease; Sydenham chorea

Indexed keywords

EID: 33645926693     PISSN: 05315131     EISSN: None     Source Type: Book Series    
DOI: 10.1016/j.ics.2005.12.004     Document Type: Article

References (6)

1. Galvin J.E., et al. Cytotoxic monoclonal antibody from rheumatic carditis reacts with human endothelium: implications in rheumatic heart disease. J. Clin. Invest. 106 (2000) 217-224
2. Roberts S., et al. Immune mechanisms in rheumatic carditis: focus on valvular endothelium. J. Infect. Dis. 183 (2001) 507-511
3. Cunningham M.W. Autoimmunity and molecular mimicry in the pathogenesis of post-streptococcal heart disease. Front Biosci. 8 (2003) s533-s543
4. Quinn A., et al. Induction of autoimmune valvular heart disease by recombinant streptococcal M protein. Infect. Immun. 69 6 (2001) 4072-4078
5. Guilherme L., et al. Human heart-filtrating T cell clones from rheumatic heart disease patients recognize both streptococcal and cardiac proteins. Circulation 92 (1995) 415-420
6. Kirvan C.A., et al. Mimicry and autoantibody-mediated neuronal cell signaling in Sydenham chorea. Nat. Med. 9 (2003) 914-920