The association between the inducible costimulatory molecules, CD 28, CD24 gene polymorphisms and multiple sclerosis

Chinese Journal of Neurology

Volumn 39, Issue 1, 2006, Pages 27-31

  Cui, Yu Zhen ^a   Xiao, Bo ^b   Zhou, Wen Bing ^b   Lin, Ai Yu ^b   Yang, Huan ^b  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b NONE

Author keywords

Antigens, differentiation, T lymphocyte; Multiple sclerosis; Polymorphism, restriction fragment length

Indexed keywords

CD24 ANTIGEN; CD28 ANTIGEN; DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; RNA; T LYMPHOCYTE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; HAPLOTYPE; HUMAN; LYMPHOCYTE DIFFERENTIATION; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

EID: 33645909236     PISSN: 10067876     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Teutsch SM, Booth DR, Bennetts BH, et al. Association of common T cell activation gene polymorphisms with multiple sclerosis in Australian patients. J Neuroimmunol, 2004, 148: 218-230.
2. 28. Nature, 1999, 397: 263-266.
3. Richter G, Burdach S. ICOS: a new costimulatory ligand/receptor pair and its role in T-cell activation. Onkologie, 2004, 27: 91-95.
4. Rottman JB, Smith T, Tonra JR, et al. The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE. Nat Immunol, 2001, 2: 605-611.
5. Kenealy SJ, Pericak-Vance MA, Haines JL. The genetic epidemiology of multiple sclerosis. J Neuroimmunol, 2003, 143: 7-12.
6. Haaning Andersen AD, Lange M, Lillevang ST. Allelic variation of the inducible costimulator (ICOS) gene: detection of polymorphisms, analysis of the promoter region, and extended haplotype estimation. Tissue Antigens, 2003, 61: 276-285.
7. 24 is a genetic modifier for risk and progression of multiple sclerosis. Proc Natl Acad Sci U S A, 2003, 100: 15041-15046.
8. Pahan K, Schmid M. Activation of nuclear factor-κB in the spinal cord of experimental allergic encephalomyelitis. Neurosci Lett, 2000, 287: 17-20.
9. Eisenhaber B, Bork P, Eisenhaber F. Sequence properties of GPI-anchored proteins near the omega-site: constraints for the polypeptide binding site of the putative transamidase. Protein Eng, 1998, 11: 1155-1161.
10. 24 controls expansion and persistence of autoreactive T cells in the central nervous system during experimental autoimmune encephalomyelitis. J Exp Med, 2004, 200: 447-458.