메뉴 건너뛰기




Volumn 27, Issue 19, 2006, Pages 3652-3662

Drug loading onto ion-exchange microspheres: Modeling study and experimental verification

Author keywords

Drug loading kinetics; Equilibrium loading and efficiency; Exact analytical solution; Experimental verification; Ion exchange microspheres; Mathematical modeling

Indexed keywords

CONCENTRATION (PROCESS); DIFFUSION; ION EXCHANGE; MATHEMATICAL MODELS;

EID: 33645879234     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2006.02.011     Document Type: Article
Times cited : (32)

References (36)
  • 2
    • 0015131940 scopus 로고
    • Polycarboxylic acid ion-exchange resin: adsorbates for taste coverage in chewable tablets
    • Borodkin S., and Sundberg D.P. Polycarboxylic acid ion-exchange resin: adsorbates for taste coverage in chewable tablets. J Pharm Sci 60 (1971) 1523-1527
    • (1971) J Pharm Sci , vol.60 , pp. 1523-1527
    • Borodkin, S.1    Sundberg, D.P.2
  • 3
    • 0000811502 scopus 로고
    • Hydrophilic albumin and dextran ion-exchange microspheres for localized chemotherapy
    • Davis S.S., Illum L., McVie J.G., and Tomolinson E. (Eds), Elsevier Science, New York
    • Goldberg E.P., Iwata H., and Longo W. Hydrophilic albumin and dextran ion-exchange microspheres for localized chemotherapy. In: Davis S.S., Illum L., McVie J.G., and Tomolinson E. (Eds). Microsphere and drug therapy: pharmaceutical, immunological and medical aspects (1984), Elsevier Science, New York 309-325
    • (1984) Microsphere and drug therapy: pharmaceutical, immunological and medical aspects , pp. 309-325
    • Goldberg, E.P.1    Iwata, H.2    Longo, W.3
  • 4
    • 33645858418 scopus 로고    scopus 로고
    • Raghunathan Y, Controlled release pharmaceutical preparations. US Patent No. 4 847 077, 1989
  • 5
    • 0025651225 scopus 로고
    • Reduced toxicity of adriamycin by incorporation into ion exchange microsphere: a therapeutic study using a rat liver tumor model
    • Codde J.P., Burton M.A., Kelleher D.K., Archer S.G., and Gray B. Reduced toxicity of adriamycin by incorporation into ion exchange microsphere: a therapeutic study using a rat liver tumor model. Aticancer Res 10 (1990) 1715-1718
    • (1990) Aticancer Res , vol.10 , pp. 1715-1718
    • Codde, J.P.1    Burton, M.A.2    Kelleher, D.K.3    Archer, S.G.4    Gray, B.5
  • 6
    • 33645849097 scopus 로고    scopus 로고
    • Kogan PW, Rudnic EM, Sequeira JA, Chaudry IA. Sustained release oral suspensions. US Patent no. 4 999 189, 1991
  • 7
    • 0026588384 scopus 로고
    • Evaluation of ion-exchange microspheres as carrier for the anticancer drug doxorubicin: in vitro studies
    • Chen Y., Burton M.A., Codde J.P., Napoli S., Martins I.J., and Gray B.N. Evaluation of ion-exchange microspheres as carrier for the anticancer drug doxorubicin: in vitro studies. J Pharm Pharmacol 44 (1992) 211-215
    • (1992) J Pharm Pharmacol , vol.44 , pp. 211-215
    • Chen, Y.1    Burton, M.A.2    Codde, J.P.3    Napoli, S.4    Martins, I.J.5    Gray, B.N.6
  • 9
    • 0029563039 scopus 로고
    • Intragastric distribution of ion-exchange resins: a drug delivery systems for the topical treatment of the gastric mucosa
    • Burton S., Washington N., Steele R.J., Mussen R., and Feely L. Intragastric distribution of ion-exchange resins: a drug delivery systems for the topical treatment of the gastric mucosa. J Pharm Pharmacol 47 (1995) 901-906
    • (1995) J Pharm Pharmacol , vol.47 , pp. 901-906
    • Burton, S.1    Washington, N.2    Steele, R.J.3    Mussen, R.4    Feely, L.5
  • 11
    • 0344177582 scopus 로고    scopus 로고
    • In vitro investigation of ionic polysaccharide for simultaneous delivery of chemosensitizer and antineoplastic agent to multidrug-resistant cells
    • Liu Z., Wu X.Y., and Bendayan R. In vitro investigation of ionic polysaccharide for simultaneous delivery of chemosensitizer and antineoplastic agent to multidrug-resistant cells. J Pharm Sci 88 (1999) 412-418
    • (1999) J Pharm Sci , vol.88 , pp. 412-418
    • Liu, Z.1    Wu, X.Y.2    Bendayan, R.3
  • 12
    • 0033812622 scopus 로고    scopus 로고
    • Synthetic and characterization of surface-hydrophobic ion-exchange microspheres and the effect of coating on drug release rate
    • Liu Z., Wu X.Y., Ballinger J.R., and Bendayan R. Synthetic and characterization of surface-hydrophobic ion-exchange microspheres and the effect of coating on drug release rate. J Pharm Sci 89 (2000) 807-817
    • (2000) J Pharm Sci , vol.89 , pp. 807-817
    • Liu, Z.1    Wu, X.Y.2    Ballinger, J.R.3    Bendayan, R.4
  • 13
    • 0035856846 scopus 로고    scopus 로고
    • A study of doxorubicin loading onto and release from sulfopropyl dextran ion-exchange microspheres
    • Liu Z., Cheung R., Wu X.Y., Ballinger J.R., Bendayan R., and Rauth A.M. A study of doxorubicin loading onto and release from sulfopropyl dextran ion-exchange microspheres. J Control Release 77 (2001) 213-224
    • (2001) J Control Release , vol.77 , pp. 213-224
    • Liu, Z.1    Cheung, R.2    Wu, X.Y.3    Ballinger, J.R.4    Bendayan, R.5    Rauth, A.M.6
  • 14
    • 0042526082 scopus 로고    scopus 로고
    • Delivery of an anticancer drug and a chemosensitizer to murine breast sarcoma by intratumoral injection of sulfopropyl dextran microspheres
    • Liu Z., Ballinger J., Rauth A.M., Bendayan B., and Wu X.Y. Delivery of an anticancer drug and a chemosensitizer to murine breast sarcoma by intratumoral injection of sulfopropyl dextran microspheres. J Pharm Pharmacol 55 (2003) 1063-1073
    • (2003) J Pharm Pharmacol , vol.55 , pp. 1063-1073
    • Liu, Z.1    Ballinger, J.2    Rauth, A.M.3    Bendayan, B.4    Wu, X.Y.5
  • 15
    • 7444229204 scopus 로고    scopus 로고
    • A new approach to the in vivo and in vitro investigation of drug release from locoregionally delivered microspheres
    • Cheung R.Y., Kuba R., Rauth A.M., Ying Y., and Wu X.Y. A new approach to the in vivo and in vitro investigation of drug release from locoregionally delivered microspheres. J Control Rel 100 (2004) 121-133
    • (2004) J Control Rel , vol.100 , pp. 121-133
    • Cheung, R.Y.1    Kuba, R.2    Rauth, A.M.3    Ying, Y.4    Wu, X.Y.5
  • 16
    • 15944377888 scopus 로고    scopus 로고
    • Cellulose acetate butyrate microcapsules containing dextran ion-exchange resins as self-propelled drug release system
    • Fundueanu G., Constantin M., Esposito E., Cortesi R., Nastruzzi C., and Menegatti E. Cellulose acetate butyrate microcapsules containing dextran ion-exchange resins as self-propelled drug release system. Biomaterials 26 (2005) 4337-4347
    • (2005) Biomaterials , vol.26 , pp. 4337-4347
    • Fundueanu, G.1    Constantin, M.2    Esposito, E.3    Cortesi, R.4    Nastruzzi, C.5    Menegatti, E.6
  • 17
    • 15944420733 scopus 로고    scopus 로고
    • Development of a microsphere system for the delivery of mitomycin C
    • Cheung R.Y., Ying Y., Wu X.Y., Rauth A.M., and Marcon N. Development of a microsphere system for the delivery of mitomycin C. Biomaterials 26 (2005) 5375-5385
    • (2005) Biomaterials , vol.26 , pp. 5375-5385
    • Cheung, R.Y.1    Ying, Y.2    Wu, X.Y.3    Rauth, A.M.4    Marcon, N.5
  • 18
    • 0004292668 scopus 로고
    • Helfferich F. (Ed), McGraw-Hill, New York
    • In: Helfferich F. (Ed). Ion exchange (1962), McGraw-Hill, New York
    • (1962) Ion exchange
  • 19
    • 0026760517 scopus 로고
    • Comparative bioavailability of a sustained release ion-exchanged hydralizine product with a potassium (cation) challenge
    • Woodworth J.R., Ludden T.M., Ludden L.K., Shepherd A.M., and Rotenberg K.S. Comparative bioavailability of a sustained release ion-exchanged hydralizine product with a potassium (cation) challenge. J Pharm Sci 81 (1992) 541-542
    • (1992) J Pharm Sci , vol.81 , pp. 541-542
    • Woodworth, J.R.1    Ludden, T.M.2    Ludden, L.K.3    Shepherd, A.M.4    Rotenberg, K.S.5
  • 21
    • 0022563405 scopus 로고
    • A lumped model for multicomponent adsorption in fixed beds
    • Moon H., and Lee W.K. A lumped model for multicomponent adsorption in fixed beds. Chem Eng Sci 41 (1986) 1995-2004
    • (1986) Chem Eng Sci , vol.41 , pp. 1995-2004
    • Moon, H.1    Lee, W.K.2
  • 22
    • 0022862316 scopus 로고
    • Multicomponent interference phenomena in ion-exchange columns
    • Yu Q., and Wang N. Multicomponent interference phenomena in ion-exchange columns. Sep Purif Methods 15 (1986) 127-158
    • (1986) Sep Purif Methods , vol.15 , pp. 127-158
    • Yu, Q.1    Wang, N.2
  • 23
    • 0023447081 scopus 로고
    • Simulation and design models for adsorption process
    • Weber W.J., and Smith E.H. Simulation and design models for adsorption process. Environ Sci Tech 21 (1987) 1040-1050
    • (1987) Environ Sci Tech , vol.21 , pp. 1040-1050
    • Weber, W.J.1    Smith, E.H.2
  • 24
    • 0026112845 scopus 로고
    • An improved finite difference method for fixed bed multicomponent sorption
    • Sun L.M., and Meunier F. An improved finite difference method for fixed bed multicomponent sorption. A I Ch E J 37 (1991) 244-254
    • (1991) A I Ch E J , vol.37 , pp. 244-254
    • Sun, L.M.1    Meunier, F.2
  • 25
    • 0027341547 scopus 로고
    • Approximation of uptake rate of spherical absorbent pellets and their application to batch adsorption calculations
    • Yao C., and Tien C. Approximation of uptake rate of spherical absorbent pellets and their application to batch adsorption calculations. Chem Eng Sci 48 (1993) 187-198
    • (1993) Chem Eng Sci , vol.48 , pp. 187-198
    • Yao, C.1    Tien, C.2
  • 26
    • 0028671391 scopus 로고
    • Mass transfer mechanisms for zeolite ion-exchange in wastewater treatment
    • Robinson S.M., Arnold W.D., and Byers C.H. Mass transfer mechanisms for zeolite ion-exchange in wastewater treatment. A I Ch E J 40 (1994) 2045-2054
    • (1994) A I Ch E J , vol.40 , pp. 2045-2054
    • Robinson, S.M.1    Arnold, W.D.2    Byers, C.H.3
  • 27
    • 0030378707 scopus 로고    scopus 로고
    • Model for Sr-Cs-Ca-Mg-Na ion-exchange uptake kinetics on chabozite
    • De Paoli S.M., and Perona J.J. Model for Sr-Cs-Ca-Mg-Na ion-exchange uptake kinetics on chabozite. A I Ch E J 42 (1996) 3434-3441
    • (1996) A I Ch E J , vol.42 , pp. 3434-3441
    • De Paoli, S.M.1    Perona, J.J.2
  • 28
    • 0030299404 scopus 로고    scopus 로고
    • Whey protein extraction by fluidized ion-exchange chromatographi simplified modelindg and economical optimization
    • Carrere H., Bascoul A., Floquet P., Wilhelm A.M., and Delmas H. Whey protein extraction by fluidized ion-exchange chromatographi simplified modelindg and economical optimization. Chem Eng J 64 (1996) 307-317
    • (1996) Chem Eng J , vol.64 , pp. 307-317
    • Carrere, H.1    Bascoul, A.2    Floquet, P.3    Wilhelm, A.M.4    Delmas, H.5
  • 29
    • 0034061084 scopus 로고    scopus 로고
    • Modeling cesium ion-exchange on fixed bed columns on crystalline silicotitanate granules
    • Latheef I.M., Huckman M.E., and Anthony R.G. Modeling cesium ion-exchange on fixed bed columns on crystalline silicotitanate granules. Ind Eng Chem Res 39 (2000) 1356-1363
    • (2000) Ind Eng Chem Res , vol.39 , pp. 1356-1363
    • Latheef, I.M.1    Huckman, M.E.2    Anthony, R.G.3
  • 30
    • 0037018972 scopus 로고    scopus 로고
    • Adsorption of an ionizable drug onto microspheres: experimental and modeling studies
    • Boudy V., Voute N., Pradeau D., and Chaumeil J.C. Adsorption of an ionizable drug onto microspheres: experimental and modeling studies. Int J Pharm 239 (2002) 13-22
    • (2002) Int J Pharm , vol.239 , pp. 13-22
    • Boudy, V.1    Voute, N.2    Pradeau, D.3    Chaumeil, J.C.4
  • 31
    • 0022440732 scopus 로고
    • Adsorption of water from aqueous ethanol using 3-Å molecular sieves
    • Teo W.K., and Ruthven D.M. Adsorption of water from aqueous ethanol using 3-Å molecular sieves. Ind Eng Chem Progress Res Dev 25 (1986) 17-21
    • (1986) Ind Eng Chem Progress Res Dev , vol.25 , pp. 17-21
    • Teo, W.K.1    Ruthven, D.M.2
  • 32
    • 0024279009 scopus 로고
    • Solute diffusion in swollen membrane: IX. Scaling laws for solute diffusion in gel
    • Lustig S.R., and Peppas N.A. Solute diffusion in swollen membrane: IX. Scaling laws for solute diffusion in gel. J Appl Poly Sci 36 (1988) 735-747
    • (1988) J Appl Poly Sci , vol.36 , pp. 735-747
    • Lustig, S.R.1    Peppas, N.A.2
  • 33
    • 0016053262 scopus 로고
    • Mass transport phenomena and models: theoretical concepts
    • Flynn G.L., Yalkowsky S.H., and Roseman T.J. Mass transport phenomena and models: theoretical concepts. J Pharm Sci 63 (1974) 497-510
    • (1974) J Pharm Sci , vol.63 , pp. 497-510
    • Flynn, G.L.1    Yalkowsky, S.H.2    Roseman, T.J.3
  • 35
    • 0038399829 scopus 로고    scopus 로고
    • Modeling and analysis of dispersed-drug release into a finite medium from sphere ensembles with boundary layer effect
    • Zhou Y., and Wu X.Y. Modeling and analysis of dispersed-drug release into a finite medium from sphere ensembles with boundary layer effect. J Control Rel 90 (2003) 23-36
    • (2003) J Control Rel , vol.90 , pp. 23-36
    • Zhou, Y.1    Wu, X.Y.2
  • 36
    • 2942557097 scopus 로고    scopus 로고
    • Theoretical analysis of drug release into a finite medium from sphere ensembles with various size and concentration distributions
    • Zhou Y., Chu J.S., and Wu X.Y. Theoretical analysis of drug release into a finite medium from sphere ensembles with various size and concentration distributions. Eur J Pharm Sci 22 (2004) 251-259
    • (2004) Eur J Pharm Sci , vol.22 , pp. 251-259
    • Zhou, Y.1    Chu, J.S.2    Wu, X.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.