Severe hyperlipidemia causes impaired renin-angiotensin system function in apolipoprotein E deficient mice

Atherosclerosis

Volumn 186, Issue 1, 2006, Pages 86-91

  Mazzolai, Lucia ^a   Korber, Martine ^a   Bouzourene, Karima ^a   Aubert, Jean François ^a   Nussberger, Jürg ^a   Stamenkovic, Ivan ^a   Hayoz, Daniel ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

ApoE mice; Atherosclerosis; Blood pressure; Renin; Two kidney one clip

Indexed keywords

APOLIPOPROTEIN E; CHOLESTEROL; LIPID; RENIN; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE MEASUREMENT; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE SEVERITY; FOOD INTAKE; GLOMERULUS; HISTOPATHOLOGY; HYPERCHOLESTEROLEMIA; HYPERLIPIDEMIA; HYPERTRIGLYCERIDEMIA; HYPOTENSION; KIDNEY; KIDNEY PERFUSION; LIPID DIET; LIPID STORAGE; MOUSE; NONHUMAN; PHENOTYPE; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; RENIN ANGIOTENSIN DISORDER; RENIN RELEASE; RENOVASCULAR HYPERTENSION; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; TISSUE INJURY; VASCULARIZATION;

ANIMALS; APOLIPOPROTEINS E; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; HYPERLIPIDEMIAS; HYPERTENSION, RENAL; IMMUNOHISTOCHEMISTRY; KIDNEY; MICE; MICE, INBRED C57BL; PROGNOSIS; RENIN; RENIN-ANGIOTENSIN SYSTEM; RISK FACTORS;

EID: 33645868654     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2005.07.017     Document Type: Article

References (16)

1. - mice. Hypertension (2004)
2. Plump A.S., Smith J.D., Hayek T., et al. Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell 71 (1992) 343-353
3. Nakashima Y., Plump A.S., Raines E.W., Breslow J.L., and Ross R. ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler Thromb 14 (1994) 133-140
4. Ghiselli G., Schaefer E.J., Gascon P., and Breser Jr. H.B. Type III hyperlipoproteinemia associated with apolipoprotein E deficiency. Science 214 (1981) 1239-1241
5. Amatruda J.M., Margolis S., and Hutchins G.M. Type 3 hyperlipoproteinemia with mesangial foam cells in renal glomeruli. Arch Pathol 98 (1974) 51-54
6. Attman P.O., Alaupovic P., and Samuelsson O. Lipoprotein abnormalities as a risk factor for progressive nondiabetic renal disease. Kidney Int Suppl 71 (1999) S14-S17
7. Keane W.F. The role of lipids in renal disease: future challenges. Kidney Int Suppl 75 (2000) S27-S31
8. Fried L.F., Orchard T.J., and Kasiske B.L. Effect of lipid reduction on the progression of renal disease: a meta-analysis. Kidney Int 59 (2001) 260-269
9. Stevenson F.T., and Kaysen G.A. Hyperlipidemia and renal disease: the use of animal models in understanding pathophysiology and approaches to treatment. Wien Klin Wochenschr 111 (1999) 307-314
10. Majumdar A., and Wheeler D.C. Lipid abnormalities in renal disease. J R Soc Med 93 (2000) 178-182
11. Appel G. Lipid abnormalities in renal disease. Kidney Int 39 (1991) 169-183
12. Samuelsson O., Mulec H., Knight-Gibson C., et al. Lipoprotein abnormalities are associated with increased rate of progression of human chronic renal insufficiency. Nephrol Dial Transplant 12 (1997) 1908-1915
13. Hunsicker L.G., Adler S., Caggiula A., et al. Predictors of the progression of renal disease in the Modification of Diet in Renal Disease Study. Kidney Int 51 (1997) 1908-1919
14. Muntner P., Coresh J., Smith J.C., Eckfeldt J., and Klag M.J. Plasma lipids and risk of developing renal dysfunction: the atherosclerosis risk in communities study. Kidney Int 58 (2000) 293-301
15. Wiesel P., Mazzolai L., Nussberger J., and Pedrazzini T. Two-kidney, one clip and one-kidney, one clip hypertension in mice. Hypertension 29 (1997) 1025-1030
16. Nussberger J., Fasanella d.T., Porchet M., et al. Repeated administration of the converting enzyme inhibitor cilazapril to normal volunteers. J Cardiovasc Pharmacol 9 (1987) 39-44