Modelling germline mosaicism and different new mutation rates simultaneously for appropriate risk calculations in families with Duchenne muscular dystrophy

Annals of Human Genetics

Volumn 70, Issue 2, 2006, Pages 237-248

  Fischer, Christine ^a,d   Gross, W ^a   Kruger J ^a   Cremer, M ^b   Vogel, F ^a   Grimm, T ^c  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d NONE   (Germany)

Author keywords

Germline mosaicism; Model of X linked lethal disease; Mutation rate ratio; Risk estimation

Indexed keywords

ALLELE; ARTICLE; DUCHENNE MUSCULAR DYSTROPHY; FAMILIAL DISEASE; FEMALE; GENE DELETION; GENE FREQUENCY; GENE LOCUS; GENE SEGREGATION; GENETIC ALGORITHM; GENETIC MODEL; GENETIC PREDISPOSITION; GENETIC RISK; GENETIC SCREENING; GENOTYPE; GERM LINE; HETEROZYGOTE; HUMAN; MALE; MATHEMATICAL COMPUTING; MOSAICISM; MUTATION RATE; MUTATIONAL ANALYSIS; PEDIGREE ANALYSIS; POINT MUTATION; PRIORITY JOURNAL; RISK ASSESSMENT;

FEMALE; GERM CELLS; HETEROZYGOTE; HUMANS; MALE; MOSAICISM; MUSCULAR DYSTROPHY, DUCHENNE; MUTATION; PEDIGREE; RISK;

EID: 33645862569     PISSN: 00034800     EISSN: 14691809     Source Type: Journal    
DOI: 10.1111/j.1469-1809.2005.00226.x     Document Type: Article

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