Transmission-reducing immunity is inversely related to age in Plasmodium falciparum gametocyte carriers

Parasite Immunology

Volumn 28, Issue 5, 2006, Pages 185-190

  Drakeley, C J ^a,b,c,d   Bousema, J T ^b   Akim, N I J ^a   Teelen, K ^b   Roeffen, W ^b   Lensen, A H ^b   Bolmer, M ^b   Eling, W ^b   Sauerwein, R W ^b  

^a IFAKARA HEALTH INSTITUTE   (Tanzania)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^d Joint Malaria Programme   (Tanzania)

Author keywords

Gametocytes; P. falciparum malaria; Pfs230; Pfs48 45; Tanzania; Transmission blocking immunity

Indexed keywords

PROTOZOON ANTIBODY;

ADOLESCENT; AGE DISTRIBUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY AFFINITY; ANTIBODY BLOOD LEVEL; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; BIOASSAY; BLOOD SAMPLING; CHILD; CONTROLLED STUDY; CORRELATION ANALYSIS; GAMETOCYTE; HUMAN; INNATE IMMUNITY; LOGISTIC REGRESSION ANALYSIS; MOSQUITO; NONHUMAN; PARASITE TRANSMISSION; PARASITE VECTOR; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; SEROLOGY; TANZANIA;

ADOLESCENT; AGE FACTORS; ANIMALS; ANOPHELES; ANTIBODIES, PROTOZOAN; CARRIER STATE; CHILD; CHILD, PRESCHOOL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; INFANT; LINEAR MODELS; MALARIA, FALCIPARUM; MALE; PLASMODIUM FALCIPARUM;

ANIMALIA; PLASMODIUM FALCIPARUM; PROTOZOA;

EID: 33645854938     PISSN: 01419838     EISSN: 13653024     Source Type: Journal    
DOI: 10.1111/j.1365-3024.2005.00818.x     Document Type: Article

References (39)

1. Graves PM Carter R Burkot TR Quakyi IA Kumar N Antibodies to Plasmodium falciparum gamete surface antigens in Papua New Guinea sera Parasite Immunol 1988 10 209 218
2. Kaslow DC Transmission-blocking immunity against malaria and other vector-borne diseases Curr Opin Immunol 1993 5 557 565
3. Ponnudurai T van Gemert GJ Bensink T Lensen AH Meuwissen JH Transmission blockade of Plasmodium falciparum: its variability with gametocyte numbers and concentration of antibody Trans R Soc Trop Med Hyg 1987 81 491 493
4. Healer J McGuinness D Carter R Riley E Transmission-blocking immunity to Plasmodium falciparum in malaria-immune individuals is associated with antibodies to the gamete surface protein Pfs230 Parasitology 1999 119 425 433
5. Ong CS Zhang KY Eida SJ et al. The primary antibody response of malaria patients to Plasmodium falciparum sexual stage antigens which are potential transmission blocking vaccine candidates Parasite Immunol 1990 12 447 456
6. Drakeley C Eling W Teelen K et al. Parasite infectivity and immunity to Plasmodium falciparum gametocytes in Gambian children Parasite Immunol 2004 26 159 165
7. Boudin C Van Der Kolk M Tchuinkam T et al. Plasmodium falciparum transmission blocking immunity under conditions of low and high endemicity in Cameroon Parasite Immunol 2004 26 105 110
8. Smith T Charlwood JD Kitua AY et al. Relationships of malaria morbidity with exposure to Plasmodium falciparum in young children in a highly endemic area Am J Trop Med Hyg 1998 59 252 257
9. Rogier C Trape JF Malaria attacks in children exposed to high transmission: who is protected? Trans R Soc Trop Med Hyg 1993 87 245 246
10. Riley EM Bennett S Jepson A et al. Human antibody responses to Pfs 230, a sexual stage-specific surface antigen of Plasmodium falciparum: non-responsiveness is a stable phenotype but does not appear to be genetically regulated Parasite Immunol 1994 2/1994 16 55 62
11. Graves PM Doubrovsky A Beckers P Antibody responses to Plasmodium falciparum gametocyte antigens during and after malaria attacks in schoolchildren from Madang, Papua New Guinea Parasite Immunol 1991 13 291 299
12. Drakeley CJ Mulder L Tchuinkam T Gupta S Sauerwein R Targett GA Transmission-blocking effects of sera from malaria-exposed individuals on Plasmodium falciparum isolates from gametocyte carriers Parasitology 1998 116 417 423
13. Roeffen W Lensen T Mulder B et al. Transmission blocking immunity as observed in a feeder system and serological reactivity to PfS48/45 and Pfs230 in field sera Mem Inst Oswaldo Cruz 1994 89 Suppl. 2 13 15
14. Roeffen W Lensen T Mulder B et al. A comparison of transmission-blocking activity with reactivity in a Plasmodium falciparum 48/45-kD molecule-specific competition enzyme-linked immunosorbent assay Am J Trop Med Hyg 1995 52 60 65
15. Graves PM Doubrovsky A Sattabongkot J Battistutta D Human antibody responses to epitopes on the Plasmodium falciparum gametocyte antigen PFS 48/45 and their relationship to infectivity of gametocyte carriers Am J Trop Med Hyg 1992 46 711 719
16. Bustamante PJ Woodruff DC Oh J Keister DB Muratova O Williamson KC Differential ability of specific regions of Plasmodium falciparum sexual-stage antigen, Pfs230, to induce malaria transmission-blocking immunity Parasite Immunol 2000 22 373 380
17. Healer J McGuinness D Hopcroft P Haley S Carter R Riley E Complement-mediated lysis of Plasmodium falciparum gametes by malaria-immune human sera is associated with antibodies to the gamete surface antigen Pfs230 Infect Immun 1997 65 3017 3023
18. Baker DA Drakeley CJ Ong CS Lulat AG Greenwood BM Targett GA Humoral immune responses in Gambians to Pfs16, an immunodominant, Plasmodium falciparum integral membrane protein Parasite Immunol 1996 18 527 533
19. Mulder B Lensen T Tchuinkam T et al. Plasmodium falciparum: membrane feeding assays and competition ELISAs for the measurement of transmission reduction in sera from Cameroon Exp Parasitol 1999 92 81 86
20. Akim NI Drakeley C Kingo T et al. falciparum gametocytemia in symptomatic patients in an area of intense perennial transmission in Tanzania Am J Trop Med Hyg 2000 63 199 203
21. Shute N The Microscopic Diagnosis of Malaria Edinburgh Churchill Livingstone 1988
22. Ponnudurai T Lensen AH Leeuwenberg AD Meuwissen JH Cultivation of fertile Plasmodium falciparum gametocytes in semi-automated systems. 1. Static cultures Trans R Soc Trop Med Hyg 1982 76 812 818
23. Vermeulen AN Ponnudurai T Beckers PJ Verhave JP Smits MA Meuwissen JH Sequential expression of antigens on sexual stages of Plasmodium falciparum accessible to transmission-blocking antibodies in the mosquito J Exp Med 1985 162 1460 1476
24. Ponnudurai T Lensen AH Van Gemert GJ Bensink MP Bolmer M Meuwissen JH Infectivity of cultured Plasmodium falciparum gametocytes to mosquitoes Parasitology 1989 98 165 173
25. Lensen A van Druten J Bolmer M van Gemert G Eling W Sauerwein R Measurement by membrane feeding of reduction in Plasmodium falciparum transmission induced by endemic sera Trans R Soc Trop Med Hyg 1996 90 20 22
26. Del Giudice G Verdini AS Pinori M et al. Detection of human antibodies against Plasmodium falciparum sporozoites using synthetic peptides J Clin Microbiol 1987 25 91 96
27. Mendis C Del Giudice G Gamage-Mendis AC et al. Anti-circumsporozoite protein antibodies measure age related exposure to malaria in Kataragama Sri Lanka Parasite Immunol 1992 14 75 86
28. Mulder B Tchuinkam T Dechering K et al. Malaria transmission-blocking activity in experimental infections of Anopheles gambiae from naturally infected Plasmodium falciparum gametocyte carriers Trans R Soc Trop Med Hyg 1994 88 121 125
29. Piper KP Hayward RE Cox MJ Day KP Malaria transmission and naturally acquired immunity to PfEMP-1 Infect Immun 1999 67 6369 6374
30. Rogers NJ Hall BS Obiero J Targett GAT Sutherland CJ A model for sequestration of the transmission stages of Plasmodium falciparum: Adhesion of gametocyte-infected erythrocytes to human bone-marrow cells Infection Immunity 2000 68 3455 3462
31. Baird JK Age-dependent characteristics of protection v. susceptibility to Plasmodium falciparum Ann Trop Med Parasitol 1998 92 367 390
32. Bousema JT Gouagna LC Drakeley CJ et al. Plasmodium falciparum gametocyte carriage in asymptomatic children in western Kenya Malar J 2004 17 18
33. Premawansa S Gamage-Mendis A Perera L Begarnie S Mendis K Carter R Plasmodium falciparum malaria transmission-blocking immunity under conditions of low endemicity as in Sri Lanka Parasite Immunol 1994 16 35 42
34. Struik SS Riley EM Does malaria suffer from lack of memory? Immunol Rev 2004 201 268 290
35. Mendis KN Carter R Transmission blocking immunity may provide clues that antimalarial immunity is largely T-independent Res Immunol 1991 142 687 690
36. Taylor RR Egan A McGuinness D et al. Selective recognition of malaria antigens by human serum antibodies is not genetically determined but demonstrates some features of clonal imprinting Int Immunol 1996 8 905 915
37. Wang L Crouch L Richie TL Nhan DH Coppel RL Naturally acquired antibody responses to the components of the Plasmodium falciparum merozoite surface protein 1 complex Parasite Immunol 2003 25 403 412
38. Read D Lensen A Bergarnie S et al. Transmission-blocking antibodies against multiple, non-variant target epitopes of the Plasmodium falciparum gamete surface protein Pfs230 are all complement fixing Parasite Immunol 1994 16 511 519
39. Roeffen W Geeraedts F Eling W et al. Transmission blockade of Plasmodium falciparum malaria by anti-Pfs230-specific antibodies is isotype dependent Infect Immunol 1995 63 467 471