Expression of thyroid hormone receptor isoforms down-regulated by thyroid hormone in human medulloblastoma cells

Endocrine Journal

Volumn 53, Issue 2, 2006, Pages 181-187

  Monden, Tsuyoshi ^a   Nakajima, Yasuyo ^b   Hashida, Tetsu ^b   Ishii, Sumiyasu ^b   Tomaru, Takuya ^b   Shibusawa, Nobuyuki ^b   Hashimoto, Koshi ^b   Satoh, Teturou ^b   Yamada, Masanobu ^b   Mori, Masatomo ^b   Kasai, Kikuo ^a  

^a DOKKYO MEDICAL UNIVERSITY   (Japan)

^b GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Cerebellum; Medulloblastoma; mRNA; Thyroid hormone; Thyroid hormone receptor

Indexed keywords

CYCLOHEXIMIDE; DACTINOMYCIN; LIOTHYRONINE; MESSENGER RNA; THYROID HORMONE; THYROID HORMONE RECEPTOR; THYROID HORMONE RECEPTOR ALPHA; THYROID HORMONE RECEPTOR ALPHA 1; THYROID HORMONE RECEPTOR ALPHA 2; THYROID HORMONE RECEPTOR BETA; THYROID HORMONE RECEPTOR BETA 1; THYROID HORMONE RECEPTOR BETA 2; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GLIOMA CELL; HORMONE ACTION; HUMAN; HUMAN CELL; MEDULLOBLASTOMA; NORTHERN BLOTTING; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN STABILITY; PROTEIN SYNTHESIS; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; RNA STABILITY; RNA TRANSCRIPTION;

BRAIN NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; MEDULLOBLASTOMA; PROTEIN BIOSYNTHESIS; PROTEIN ISOFORMS; RECEPTORS, THYROID HORMONE; RNA, MESSENGER; THYROID HORMONE RECEPTORS ALPHA; THYROID HORMONE RECEPTORS BETA; TRIIODOTHYRONINE; TUMOR CELLS, CULTURED;

EID: 33645849219     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.53.181     Document Type: Article

References (35)

1. Oppenheimer JH, Schwartz HL (1997) Molecular basis of thyroid hormone-dependent brain development. Endocr Rev 18: 462-475.
2. Thompson CC, Weinberger C, Lebo R, Evans RM (1987) Identification of a novel thyroid hormone receptor expressed in the mammalian central nervous system. Science 237: 1610-1614.
3. Bradley DJ, Young WS 3rd, Weinberger C (1989) Differential expression of α and β thyroid hormone receptor genes in rat brain and pituitary. Proc Natl Acad Sci USA 86: 7250-7254.
4. Onate SA, Tsai SY, Tsai MJ, O'Malley WO (1995) Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270: 1354-1357.
5. Monden T, Wondisford FE, Hollenberg AN (1997) Isolation and characterization of a novel ligand-dependent thyroid hormone receptor-coactivating protein. J Biol Chem 272: 29834-29841.
6. Kariya Y, Moriya T, Suzuki T, Chiba M, Ishida K, Takeyama J, Endoh M, Watanabe M, Sasano H (2005) Sex steroid hormone receptors in human skin appendage and its neoplasms. Endocr J 52: 317-325.
7. Cook CB, Koenig RJ (1990) Expression of erbAα and β mRNAs in regions of adult rat brain. Mol Cell Endocrinol 70: 13-20.
8. Hodin RA, Lazar MA, Chin WW (1990) Differential and tissue-specific regulation of the multiple rat c-erbA messenger RNA species by thyroid hormone. J Clin Invest 85: 101-105.
9. Lechan RM, Qi Y, Berrodin TJ, Davis KD, Schwartz HL, Strait KA, Oppenheimer JH, Lazar MA (1993) Immunocytochemical delineation of the thyroid hormone receptor β2-like immunoreactivity in the rat central nervous system. Endocrinology 132: 2461-2469.
10. Sherer TT, Sylvester SR, Bull RJ (1993) Differential expression of c-erbA mRNAs in the developing cerebellum and cerebral cortex of the rat. Biol Neonate 63: 26-34.
11. Forrest D, Hallböök F, Persson H, Vennström B (1991) Distinct functions for thyroid hormone receptors α and β in brain development indicated by differential expression of receptor genes. EMBO J 10: 269-275.
12. Williams GR (2000) Cloning and characterization of two novel thyroid hormone receptor β isoforms. Mol Cell Biol 20: 8329-8342.
13. Strait KA, Schwartz HL, Seyhold VS, Ling NC, Oppenheimer JH (1991) Immunofluorescence localization of thyroid hormone receptor protein β1 and variant β2 in selected tissues: cerebellar Purkinje cells as a model for β1 receptor-mediated developmental effects of thyroid hormone in brain. Proc Natl Acad Sci USA 88: 3887-3891.
14. Heuer H, Mason CA (2003) Thyroid hormone induces cerebellar Purkinnje cell dendritic development via the thyroid hormone receptor α1. Neuroscience 23: 10604-10612.
15. Strait KA, Zou L, Oppenheimer JH (1992) β1 isoform-specific regulation of a triiodothyronine-induced gene during cerebellar development. Mol Endocrinol 6: 1874-1880.
16. Hashida T, Yamada M, Hashimoto K, Shibusawa N, Monden T, Satoh T, Mori M (2002) A novel TRH-PFTAIRE protein kinase 1 pathway in the cerebellum: subtractive hybridization analysis of TRH-deficient mice. Endocrinology 143: 2802-2811.
17. Koibuchi N, Jingu H, Iwasaki T, Chin WW (2003) Current perspectives on the role of thyroid hormone in growth and development of cerebellum. Cerebellum 2: 279-289.
18. Pastor R, Bernal J, Rodriguez-Peña A (1994) Unliganded c-erbA/thyroid hormone receptor induced trkB expression in neuroblastoma cells. Oncogene 9: 1081-1089.
19. Lebel JM, Dussault JH, Puymirat J (1994) Overexpression of the β1 thyroid hormone receptor induces differentiation in neuro-2a cells. Proc Natl Acad Sci USA 91: 2644-2648.
20. Li M, Boyages SC (1996) Detection of extended distribution of β2-thyroid hormone receptor messenger ribonucleic acid (RNA) in adult rat brain using complementary RNA in situ hybridization histochemistry. Endocrinology 137: 1272-1275.
21. Katz D, Lazar MA (1993) Dominant negative activity of an endogenous thyroid hormone receptor variant (a2) is due to competition for binding sites on target genes. J Biol Chem 268: 20904-20910.
22. Strait KA, Schwartz HL, Perez-Castillo A, Oppenheimer JH (1990) Relationship of c-erbA mRNA content to tissue triiodothyronine nuclear binding capacity and function in developing and adult rats. J Biol Chem 265: 10514-10521.
23. Hodin RA, Meng S, Chamberlain SM (1994) Thyroid hormone responsiveness is developmentally regulated in the rat small intestine: a possible role for the α-2 receptor variant. Endocrinology 135: 564-568.
24. Sadow PM, Chassande O, Koo EK, Gauthier K, Samarut J, Xu J, O'Malley BW, Weiss RE (2003) Regulation of expression of thyroid hormone receptor isoforms and coactivator in liver and heart by thyroid hormone. Mol Cell Endocrinol 203: 65-75.
25. Monden T, Yamada Y, Konaka S, Satoh T, Ezawa T, Iwasaki T, Mori M (1995) Transcriptional down-regulation by epidermal growth factor of TRH receptor mRNA in rat pituitary cells. J Mol Endocrinol 15: 73-79.
26. Guhaniyogi J, Brewer G (2001) Regulation of mRNA stability in mammalian cells. Gene 265: 11-23.
27. Aniello FA, Couchie D, Brioux A-M, Gripois D, Nunez J (1991) Proc Natl Acad Sci USA 88: 4035-4039.
28. Liu D, Waxman DJ (2002) Post-transcriptional regulation of hepatic NADPH-cytochrome P450 reductase by thyroid hormone: independent effects on poly(A) tail length and mRNA stability. Mol Pharmacol 61: 1089-1096.
29. Baas D, Puymirat J, Sarlieve LL (1998) Posttranscriptional regulation of oligodendroglial thyroid hormone (T3) receptor β1 by T3. Int J Dev Neurosci 16: 461-467.
30. Cuadrado A, Navarro-Yubero C, Furneaux H, Munoz A (2003) Neuronal HuD gene encoding a mRNA stability regulator is transcriptionally repressed by thyroid hormone. J Neurochem 86: 763-773.
31. Hastings ML, Ingle HA, Lazar MA, Munroe SH (2000) Post-transcriptional regulation of thyroid hormone receptor expression by cis-acting sequenced and a naturally occurring antisense RNA. J Biol Chem 275: 11507-11513.
32. Lazar MA, Chin WW (1988) Regulation of two c-erbA messenger ribonucleic acids in rat GH3 cells by thyroid hormone. Mol Endocrinol 2: 479-484.
33. Lebel JM, L'herault S, Dussault JH, Puymirat J (1993) Thyroid hormone up-regulates thyroid hormone receptor b gene expression in rat cerebral hemisphere astrocyte cultures. Glia 9: 105-112.
34. Frankton S, Harvey CB, Gleason LM, Fadel A, Williams GR (2004) Multiple messenger ribonucleic acid variants regulate cell-specific expression of human thyroid hormone receptor β1. Mol Endocrinol 18: 1631-1642.
35. Kenessey A, Ojamaa K (2005) Ligand-mediated decrease of thyroid hormone receptor-α1 in cardiomyocytes by proteosome-dependent degradation and altered mRNA stability. Am J Physiol Heart Circ Physiol 288: H813-H821.