A novel 1-tert-butoxy-2-tert-butoxycarbonyl-1,2-dihydroisoquinoline (BBDI)-catalyzed esterification of N-protected amino acids with nearly equimolar amounts of alcohols in the presence of Boc2O

Tetrahedron Letters

Volumn 47, Issue 18, 2006, Pages 3099-3102

  Saito, Yukako ^a   Watanabe, Tomokazu ^a   Takahata, Hiroki ^a  

^a TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 TERT BUTOXY 2 TERT BUTOXYCARBONYL 1,2 DIHYDROISOQUINOLINE; ALCOHOL; AMINO ACID; ISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; ESTERIFICATION; PROTECTION;

EID: 33645842228     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2006.02.149     Document Type: Article

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14. 4) and the solvent evaporated to give the crude compound, which was purified by chromatography on a short column using a mixture of n-hexane and ethyl acetate as eluant to yield N-protected amino acid ester.
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