Loosening addiction's deadly grip

EMBO Reports

Volumn 7, Issue 2, 2006, Pages 140-142

  Brower, Vicki ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ARIPIPRAZOLE; CENTRAL DEPRESSANT AGENT; CENTRAL STIMULANT AGENT; COCAINE; DOPAMINE; DOPAMINE 3 RECEPTOR STIMULATING AGENT; ILLICIT DRUG; METHAMPHETAMINE; METHYLPHENIDATE; MODAFINIL; NALTREXONE; NICOTINE; OPIATE; PRAMIPEXOLE; TALAMPANEL; DRUG;

ALCOHOL CONSUMPTION; ALCOHOLISM; ANXIETY; ARTICLE; ATTENTION DEFICIT DISORDER; BRAIN DISEASE; CLINICAL TRIAL; COCAINE DEPENDENCE; DRUG ABUSE; DRUG DEPENDENCE; DRUG DOSE REDUCTION; HUMAN; HYPERSEXUALITY; MEDICAL RESEARCH; MENTAL DISEASE; NEUROLOGIC DISEASE; NONHUMAN; OVERNUTRITION; PARKINSON DISEASE; PATHOLOGICAL GAMBLING; PRESCRIPTION; PRIORITY JOURNAL; PUBLIC HEALTH; REINFORCEMENT; SOCIAL PROBLEM; ADDICTION; BRAIN LEVEL; CHEMICALLY INDUCED DISORDER; CHRONIC DISEASE; DRINKING BEHAVIOR; DRUG EFFECT;

ALCOHOL DRINKING; BEHAVIOR, ADDICTIVE; BIOMEDICAL RESEARCH; BRAIN CHEMISTRY; CHRONIC DISEASE; HUMANS; NERVOUS SYSTEM DISEASES; NICOTINE; PHARMACEUTICAL PREPARATIONS; SUBSTANCE-RELATED DISORDERS;

EID: 33645834104     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/sj.embor.7400635     Document Type: Article

References (19)

1. CASA (2005) Under the Counter: The Diversion and Abuse of Controlled Prescription Drugs in the US. New York, NY, USA: Columbia University. www.casacolumbia.org
2. Dodd ML, Klos KJ, Bower JH, Geda YE, Josephs KA, Ahlskog JE (2005) Pathological gambling caused by drugs used to treat Parkinson disease. Arch Neurol 62: 1377-1381
3. Hattori S, Naoi M, Nishino H (1994) Striatal dopamine turnover during treadmill running in the rat: Relation to the speed of running. Brain Res Bull 35: 41-49
4. Holden C (2003) Excited by glutamate. Science 300: 1866-1868
5. Kalivas PW, Volkow ND (2005) The neural basis of addiction: A pathology of motivation and choice. Am J Psychiatry 162: 1403-1413
6. Koob GF, Le Moal M (2001) Drug addiction, dysregulation of reward, and allostasis. Neuropsychopharmacology 24: 97-129
7. Kotler M, Cohen H, Segman R, Gritsenko I, Nemanov L, Lerer B, Kramer I, Zer-Zion M, Kletz I, Ebstein RP (1997) Excess dopamine D4 receptor (D4DR) exon III seven repeat allele in opioid-dependent subjects. Mol Psychiatry 2: 251-254
8. Kremer I, Bachner-Melman R, Reshef A, Broude L, Nemanov L, Gritsenko I, Heresco-Levy U, Elizur Y, Ebstein RP (2005) Association of the serotonin transporter gene with smoking behavior. Am J Psychiatry 162: 924-930
9. McFarland K, Lapish CC, Kalivas PW (2003) Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior. J Neurosci 23: 3531-3537
10. Morgan D, Grant KA, Gage HD, Mach RH, Kaplan JR, Prioleau O, Nader SH, Buchheimer N, Ehrenkaufer RL, Nader MA (2002) Social dominance in monkeys: Dopamine D2 receptors and cocaine self-administration. Nat Neurosci 5: 169-174
11. Nader MA, Czoty PW (2005) PET imaging of dopamine D2 receptors in monkey models of cocaine abuse: Genetic predisposition versus environmental modulation. Am J Psychiatry 162: 1473-1482
12. O'Brien CP (2005) Anticraving medications for relapse prevention: A possible new class of psychoactive medications. Am J Psychiatry 162: 1423-1431
13. Pandey SC, Zhang H, Roy A, Xu T (2005) Deficits in amygdaloid CAMP-responsive element-binding protein signaling play a role in genetic predisposition to anxiety and alcoholism. J Clin Invest 115: 2762-2773
14. Robinson TE, Berridge KC (1993) The neural basis of drug craving: An incentive-sensitization theory of addiction. Brain Res Rev 18: 247-291
15. Thanos PK et al (2004) DRD2 gene transfer into the nucleus accumbens core of the alcohol preferring and nonpreferring rats attenuates alcohol drinking. Alcohol Clin Exp Res 28: 720-728
16. Volkow ND, Swanson JM (2003) Variables that affect the clinical use and abuse of methylphenidate in the treatment of ADHD. Am J Psychiatry 160: 1909-1918
17. Volkow ND et al (2001) Low level of brain dopamine D2 receptors in methamphetamine abusers: Association with metabolism in the orbitofrontal cortex. Am J Psychiatry 158: 2015-2021
18. Wang GJ, Volkow ND, Logan J, Pappas NR, Wong CT, Zhu W, Netusil N, Fowler JS (2001) Brain dopamine and obesity. Lancet 357: 354-357
19. Wilson WM, Marsden CA (1995) Extracellular dopamine in the nucleus accumbens of the rat during treadmill running. Acta Physiol Scand 155: 465-466