Diagnosis and therapy of sepsis. Guidelines of the German Sepsis Society Inc. and the German Interdisciplinary Society for Intensive and Emergency Medicine;Diagnose und therapie der sepsis. S2-leitlinien der Deutschen Sepsis-Gesellschaft e.V. (DSG) und der Deutschen Interdisziplinären Vereinigung für Intensiv- und Notfallmedizin (DIVI)

Internist

Volumn 47, Issue 4, 2006, Pages 356-373

  Reinhart, K ^a   Brunkhorst, F ^a   Bone, H ^a   Gerlach, H ^a   Grundling M ^a   Kreymann, G ^a   Kujath, P ^a   Marggraf, G ^a   Mayer, K ^a   Meier Hellmann, A ^a   Peckelsen, C ^a   Putensen, C ^a   Quintel, M ^a   Ragaller, M ^a   Rossaint, R ^a   Stuber F ^a   Weiler, N ^a   Welte, T ^a   Werdan, K ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

Author keywords

Diagnosis; Germany; Guidelines; Sepsis; Treatment

Indexed keywords

ADRENALIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMPHOTERICIN B; ANTITHROMBIN; BETA LACTAM ANTIBIOTIC; CARBAPENEM; CASPOFUNGIN; CEFEPIME; CEFTAZIDIME; DOBUTAMINE; DOPAMINE; DOPEXAMINE; DROTRECOGIN; FLUCONAZOLE; FLUOCINOLONE; FOSFOMYCIN; FUSIDATE SODIUM; GLUCOCORTICOID; HYDROCORTISONE; HYPERTENSIVE AGENT; LINEZOLID; MEROPENEM; OXAZOLIDINONE DERIVATIVE; PIPERACILLIN; RIFAMPICIN; TEICOPLANIN; UNINDEXED DRUG; VANCOMYCIN; VASOPRESSIN; VORICONAZOLE;

ACUTE CHOLECYSTITIS; ACUTE HEART INFARCTION; ADJUVANT THERAPY; ANALGESIA; ANTIBIOTIC THERAPY; BACTERIAL INFECTION; BLOOD; CANDIDIASIS; CLINICAL TRIAL; COST BENEFIT ANALYSIS; DEATH; DISEASE SEVERITY; EMERGENCY CARE; GERMANY; HEALTH CARE SYSTEM; HEMODYNAMICS; HUMAN; HYPOTENSION; INFECTION CONTROL; INFECTION PREVENTION; INSULIN TREATMENT; INTENSIVE CARE; META ANALYSIS; MYCOSIS; NEUROMUSCULAR BLOCKING; PNEUMONIA; POSITIVE END EXPIRATORY PRESSURE; PRACTICE GUIDELINE; REVIEW; SEDATION; SEPSIS; SEPTIC SHOCK; SYSTEMATIC REVIEW; TREATMENT PLANNING;

DELIVERY OF HEALTH CARE, INTEGRATED; GERMANY; HUMANS; PHYSICIAN'S PRACTICE PATTERNS; PRACTICE GUIDELINES; PRACTICE GUIDELINES AS TOPIC; SEPSIS;

EID: 33645833029     PISSN: 00209554     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00108-006-1595-x     Document Type: Review

References (30)

1. ISIS-4 (Fourth International Study of Infarct Survival) Collaborative Group (1995) ISIS-4: a randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58,050 patients with suspected acute myocardial infarction. Lancet 345: 669-685
2. Sackett DL (1989) Rules of evidence and clinical recommendations on the use of antithrombotic agents. Chest 95 (Suppl): 2S-4S
3. Martin GS, Mannino DM, Eaton S, Moss M (2003) The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 348: 1546-1554
4. Vincent JL, Bihari DJ, Suter PM et al. (1995) The prevalence of nosocomial infection in intensive care units in Europe. Results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC International Advisory Committee. JAMA 274: 639-644
5. ACCP/SCCM Consensus Conference Committee (1992) Definition for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 20: 864-874
6. Zeni F, Freeman B, Natanson C (1997) Anti-inflammatory therapies to treat sepsis and septic shock: a reassessment. Crit Care Med 25: 1095-1100
7. Singh N, Rogers P, Atwood CW, Wagener MM, Yu VL (2000) Short-course empiric antibiotic therapy for patients with pulmonary infiltrates in the intensive care unit. A proposed solution for indiscriminate antibiotic prescription. Am J Respir Crit Care Med 162: 505-511
8. Luyt CE, Chastre J, Fagon JY (2004) Value of the clinical pulmonary infection score for the identification and management of ventilator-associated pneumonia. Intensive Care Med 30: 844-852
9. Llewelyn M, Cohen J (2001) Diagnosis of infection in sepsis. Intensive Care Med 27 (Suppl 1): S10-32
10. Heyland DK, Novak F, Drover JW, Jain M, Su X, Suchner U (2001) Should immunonutrition become routine in critically ill patients? A systematic review of the evidence. JAMA 286: 944-953
11. van den Berghe G, Wouters P, Weekers F et al. (2001) Intensive insulin therapy in the critically ill patients. N Engl J Med 345: 1359-1367
12. de Jonge E, Schultz MJ, Spanjaard L et al. (2003) Effects of selective decontamination of digestive tract on mortality and acquisition of resistant bacteria in intensive care: a randomised controlled trial. Lancet 362: 1011-1016
13. Dellinger RP, Carlet J, Masur H et al. (2004) Surviving sepsis campaign for management of severe sepsis and septic shock. Crit Care Med 32: 858-872
14. Paul M, Benuri-Silbiger I, Soares-Weiser K, Leibovici L (2004) Beta lactam monotherapy versus beta lactam-aminoglycoside combination therapy for sepsis in immunocompetent patients: systematic review and meta-analysis of randomised trials. BMJ 328: 668
15. Rivers E, Nguyen B, Havstad S et al. (2001) Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345: 1368-1377
16. Finfer S, Bellomo R, Boyce N, French J, Myburgh J, Norton R (2004) A comparison of albumin and saline for fluid resuscitation in the intensive care unit. N Engl J Med 350: 2247-2256
17. Schierhout G, Roberts I (1998) Fluid resuscitation with colloid or crystalloid solutions in critically ill patients: a systematic review of randomised trials. BMJ 316: 961-964
18. Meier-Hellmann A (2000) Hämodynamische Stabilisierung in der Sepsis. Anästhesiol Intensivmed 41: 601-613
19. Gattinoni L, Brazzi L, Pelosi P et al. (1995) A trial of goal-oriented hemodynamic therapy in critically ill patients. SvO2 Collaborative Group. N Engl J Med 333: 1025-1032
20. Bellomo R, Chapman M, Finfer S, Hickling K, Myburgh J (2000) Low-dose dopamine in patients with early renal dysfunction: a placebo-controlled randomised trial. Australian and New Zealand Intensive Care Society (ANZICS) Clinical Trials Group. Lancet 356: 2139-2143
21. Marik PE (2002) Low-dose dopamine: a systematic review. Intensive Care Med 28: 877-883
22. Acute Respiratory Distress Syndrome Network (2000) Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 342: 1301-1308
23. Ely EW, Baker AM, Dunagan DP et al. (1996) Effect on the duration of mechanical ventilation of identifying patients capable of breathing spontaneously. N Engl J Med 335: 1864-1869
24. Annane D, Sebille V, Charpentier C et al. (2002) Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 288: 862-871
25. Bernard GR, Vincent JL, Laterre PF et al. (2001) Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 344: 699-709
26. European Medicines Agency (2005) Committee for Medicinal Products for Human Use.http://www. emea.eu.int/pdfs/human/press/pr/12130705en.pdf
27. Pildal J, Gotzsche PC (2004) Polyclonal immunoglobulin for treatment of bacterial sepsis: a systematic review. Clin Infect Dis 39: 38-46
28. Heyland DK, Dhaliwal R, Suchner U, Berger MM (2005) Antioxidant nutrients: a systematic review of trace elements and vitamins in the critically ill patient. Intensive Care Med 31: 327-337
29. Kellum JA, Angus DC, Johnson JP et al. (2002) Continuous versus intermittent renal replacement therapy: a meta-analysis. Intensive Care Med 28: 29-37
30. Hébert PC, Wells G, Blajchman MA et al. (1999) A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. N Engl J Med 340: 409-417