Mercury in dental amalgam - A neurotoxic risk?

JAMA

Volumn 295, Issue 15, 2006, Pages 1835-1836

  Needleman, Herbert L ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COPROPORPHYRINOGEN OXIDASE; DENTAL ALLOY; MERCURY;

ATTENTION; BEHAVIOR; CLINICAL FEATURE; COGNITION; DENTAL SURGERY; EDITORIAL; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; HIGH RISK POPULATION; HUMAN; LEAD POISONING; MEMORY; MERCURIALISM; NEUROPSYCHOLOGY; NEUROTOXICITY; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; TOOTH FILLING; URINARY EXCRETION; VISUOMOTOR COORDINATION; CHILD; NOTE;

CHILD; DENTAL AMALGAM; HUMANS; MERCURY POISONING, NERVOUS SYSTEM;

EID: 33645831395     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.295.15.1835     Document Type: Editorial

References (13)

1. Bellinger DC, Trachtenberg F, Barregard L, et al. Neuropsychological and renal effects of dental amalgam in children: a randomized clinical trial. JAMA. 2006;295:1775-1783.
2. DeRouen TA, Martin MD, Leroux BG, et al. Neurobehavioral effects of dental amalgam in children: a randomized clinical trial. JAMA. 2006;295:1784-1792.
3. Ratcliff HE, Swanson GM, Fisher LJ. Human exposure to mercury: a critical assessment of adverse health effects. J Toxicol Environ Health. 1996;49:221-270.
4. Vimy MJ, Lorscheider FL. Intra-oral air mercury released from dental amalgam. J Dent Res. 1985;64:1069-1071.
5. Shapiro IM, Cornblath DR, Sumner AJ, et al. Neurophysiological and neuropsychological function in mercury-exposed dentists. Lancet. 1982;1:1147-1150.
6. Thompson CM, Markesbery WR, Ehmann WD, Mao YX, Vance DE. Regional brain trace-element studies in Alzheimer's disease. Neurotoxicology. 1988;9:1-7.
7. Echeverria D, Woods JS, Heyer NJ, et al. The association between a genetic polymorphism of coproporphyrinogen oxidase, dental mercury exposure and neurobehavioral response in humans. Neurotoxicol Teratol. 2006;28:39-48.
8. Oshima H, Nakamura M, Yasuda K, Yamagishi N, Hatayama T. Stress protein assay for the evaluation of cytotoxicity of dental amalgam. J Mater Sci Mater Med. 2004;15:1-5.
9. Pendergrass JC, Haley BE, Vimy MJ, Winfield SA, Lorscheider FL. Mercury vapor inhalation inhibits binding of GTP to tubulin in rat brain: similarity to a molecular lesion in Alzheimer diseased brain. Neurotoxicology. 1997;18:315-324.
10. Needleman H. Lead poisoning. Annu Rev Med. 2004;55:209-222.
11. Needleman HL, Gunnoe C, Leviton A, et al. Deficits in psychological and classroom performance of children with elevated dentine lead levels [correction in N Engl J Med. 1994;331:616-617]. N Engl J Med. 1979;300:689-695.
12. Lanphear BP, Hornung R, Khoury J, et al. Low-level environmental lead exposure and children's intellectual function: an international pooled analysis. Environ Health Perspect. 2005;113:894-899.
13. Lorscheider FL, Vimy MJ, Summers AO. Mercury exposure from "silver" tooth fillings: emerging evidence questions a traditional dental paradigm. FASEB J. 1995;9:504-508.