Chemoprevention of Colorectal Neoplasia in Ulcerative Colitis: The Effect of 6-Mercaptopurine

Clinical Gastroenterology and Hepatology

Volumn 4, Issue 4, 2006, Pages 521-

  Allgayer, Hubert ^a   Kruis, Wolfgang ^b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

METHYLTESTOSTERONE;

ANTINEOPLASTIC ACTIVITY; CANCER GROWTH; CHEMOPROPHYLAXIS; COLORECTAL TUMOR; HEALTH SURVEY; HISTOLOGY; HUMAN; INFLAMMATION; LETTER; ULCERATIVE COLITIS;

6-MERCAPTOPURINE; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIMETABOLITES, ANTINEOPLASTIC; AZATHIOPRINE; COLITIS, ULCERATIVE; COLORECTAL NEOPLASMS; HUMANS; MESALAMINE;

EID: 33645831324     PISSN: 15423565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cgh.2005.12.030     Document Type: Letter

References (6)

1. Matula S., Croog V., Itzkowitz S., et al. Chemoprevention of colorectal neoplasia in ulcerative colitis. the effect of 6-mercaptopurine. Clin Gastroenterol Hepatol 3 (2005) 1015-1021
2. Pinczowski D., Ekbom A., Baron J., et al. Risk factors for colorectal cancer in patients with ulcerative colits. a case-control study. Gastroenterology 107 (1994) 1117-1120
3. Rutter M., Saunders B., Wilkinson K., et al. Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis. Gastroenterology 126 (2004) 451-459
4. Allgayer H., and Kruis W. Aminosalicylates. potential antineoplastic actions in colon cancer prevention. Scand J Gastroenterol 37 (2002) 125-131
5. Okayasu I., Ohkusa T., Kaijura K., et al. Promotion of colorectal neoplasia in experimental murine ulcerative colitis. Gut 39 (1996) 87-92
6. Eberhart C.E., Coffey R.J., Radhika A., et al. Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 107 (1994) 11183-11188