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Volumn 2005, Issue 284, 2005, Pages
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A rationally designed small molecule that inhibits the HIF-1alpha-ARNT heterodimer from binding to DNA in vivo.
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Author keywords
[No Author keywords available]
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Indexed keywords
ANGIOGENESIS INHIBITOR;
ANTINEOPLASTIC AGENT;
ARNT PROTEIN, HUMAN;
CONGOCIDINE;
DISTAMYCIN A;
DNA;
HIF1A PROTEIN, HUMAN;
HYPOXIA INDUCIBLE FACTOR 1ALPHA;
HYPOXIA INDUCIBLE FACTOR 1BETA;
NYLON;
TRANSCRIPTION FACTOR;
VASCULOTROPIN A;
BIOSYNTHESIS;
CELL HYPOXIA;
CHEMICAL STRUCTURE;
CHEMISTRY;
CONFORMATION;
DRUG ANTAGONISM;
DRUG DESIGN;
DRUG EFFECT;
GENE EXPRESSION REGULATION;
GENETIC TRANSCRIPTION;
GENETICS;
HUMAN;
METABOLISM;
NEOVASCULARIZATION (PATHOLOGY);
NUCLEOTIDE SEQUENCE;
PROTEIN BINDING;
REPORTER GENE;
REVIEW;
STRUCTURE ACTIVITY RELATION;
SYNTHESIS;
ANGIOGENESIS INHIBITORS;
ANTINEOPLASTIC AGENTS;
ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR;
BASE SEQUENCE;
CELL HYPOXIA;
DISTAMYCINS;
DNA;
DNA, NEOPLASM;
DRUG DESIGN;
GENE EXPRESSION REGULATION;
GENE EXPRESSION REGULATION, NEOPLASTIC;
GENES, REPORTER;
HUMANS;
HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT;
MODELS, MOLECULAR;
MOLECULAR STRUCTURE;
NEOVASCULARIZATION, PATHOLOGIC;
NETROPSIN;
NUCLEIC ACID CONFORMATION;
NYLONS;
PROTEIN BINDING;
STRUCTURE-ACTIVITY RELATIONSHIP;
TRANSCRIPTION FACTORS;
TRANSCRIPTION, GENETIC;
VASCULAR ENDOTHELIAL GROWTH FACTOR A;
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EID: 33645821109
PISSN: None
EISSN: 15258882
Source Type: Journal
DOI: None Document Type: Review |
Times cited : (8)
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References (11)
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