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Volumn 7, Issue 5, 2006, Pages 607-615

Sativex®: Clinical efficacy and tolerability in the treatment of symptoms of multiple sclerosis and neuropathic pain

Author keywords

Cannabis; Multiple sclerosis; Neuropathic pain; Sativex ; Spasticity

Indexed keywords

11 HYDROXYDRONABINOL; BACLOFEN; CANNABIDIOL; CANNABIS; DANTROLENE; DRONABINOL; PLACEBO; TETRAHYDROCANNABINOL; TIZANIDINE; ANALGESIC AGENT; CANNABINOID; PLANT EXTRACT; TETRAHYDROCANNABINOL CANNABIDIOL COMBINATION; TETRAHYDROCANNABINOL-CANNABIDIOL COMBINATION;

EID: 33645816506     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.7.5.607     Document Type: Article
Times cited : (137)

References (28)
  • 2
    • 0022531821 scopus 로고
    • Disability disease duration and rehabilitation service needs in multiple sclerosis: Patient perspectives
    • KRAFT GH, FREAL JE, CORYLL JK: Disability disease duration and rehabilitation service needs in multiple sclerosis: patient perspectives. Arch. Phys. Med. Rehabil. (1986) 67:164-178.
    • (1986) Arch. Phys. Med. Rehabil. , vol.67 , pp. 164-178
    • Kraft, G.H.1    Freal, J.E.2    Coryll, J.K.3
  • 4
    • 18444376760 scopus 로고    scopus 로고
    • International union of pharmacology. XXVII. Classification of cannabinoid receptors
    • HOWLETT AC, BARTH F, BONNER TI et al.: International union of pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacol. Rev. (2002) 54(2):161-202.
    • (2002) Pharmacol. Rev. , vol.54 , Issue.2 , pp. 161-202
    • Howlett, A.C.1    Barth, F.2    Bonner, T.I.3
  • 5
    • 0030611978 scopus 로고    scopus 로고
    • Pharmacology of cannabinoid CB1 and CB2 receptors
    • PERTWEE RG: Pharmacology of cannabinoid CB1 and CB2 receptors. Pharmacol. Ther.(1997) 74:129-180.
    • (1997) Pharmacol. Ther. , vol.74 , pp. 129-180
    • Pertwee, R.G.1
  • 6
    • 0035150352 scopus 로고    scopus 로고
    • Cannabinoid receptors and pain
    • PERTWEE RG: Cannabinoid receptors and pain. Prog. Neurobiol. (2001) 63:569-611.
    • (2001) Prog. Neurobiol. , vol.63 , pp. 569-611
    • Pertwee, R.G.1
  • 7
    • 14644445310 scopus 로고    scopus 로고
    • Development of cannabis-based medicines: Risk, benefit and serendipity
    • Guy GW, Whittle BA, Robson PJ (Eds). Pharmaceutical Press, London, UK
    • WHITTLE BA, GUY GW: Development of cannabis-based medicines: risk, benefit and serendipity. In: The medicinal use of cannabis and cannabinoids. Guy GW, Whittle BA, Robson PJ (Eds). Pharmaceutical Press, London, UK (2004):427-466.
    • (2004) The Medicinal Use of Cannabis and Cannabinoids , pp. 427-466
    • Whittle, B.A.1    Guy, G.W.2
  • 8
    • 85071447718 scopus 로고    scopus 로고
    • Cannabis and cannabis extracts: Greater than the sum of their parts?
    • MCPARTLAND JM, RUSSO EB: Cannabis and cannabis extracts: greater than the sum of their parts? J. Cannabis Therapeutics (2001) 1(3-4):103-132.
    • (2001) J. Cannabis Therapeutics , vol.1 , Issue.3-4 , pp. 103-132
    • Mcpartland, J.M.1    Russo, E.B.2
  • 10
    • 27444434456 scopus 로고    scopus 로고
    • The breeding of cannabis cultivars for pharmaceutical end uses
    • Guy GW, Whittle BA, Robson PJ (Eds). Pharmaceutical Press, London, UK
    • DE MEIJER E: The breeding of cannabis cultivars for pharmaceutical end uses. In: The medicinal use of cannabis and cannabinoids. Guy GW, Whittle BA, Robson PJ (Eds). Pharmaceutical Press, London, UK (2004):55-69.
    • (2004) The Medicinal Use of Cannabis and Cannabinoids , pp. 55-69
    • De Meijer, E.1
  • 11
    • 14844340153 scopus 로고    scopus 로고
    • The medicinal use of cannabis in the UK: Results of a nationwide survey
    • WARE MA, ADAMS H, GUY GW: The medicinal use of cannabis in the UK: results of a nationwide survey. Int. J. Clin. Pract. (2005) 59:291-295.
    • (2005) Int. J. Clin. Pract. , vol.59 , pp. 291-295
    • Ware, M.A.1    Adams, H.2    Guy, G.W.3
  • 12
    • 0035135376 scopus 로고    scopus 로고
    • Therapeutic aspects of cannabis and cannabinoids
    • ROBSON P: Therapeutic aspects of cannabis and cannabinoids. Br. J. Psychiatry (2001) 178:107-115.
    • (2001) Br. J. Psychiatry , vol.178 , pp. 107-115
    • Robson, P.1
  • 13
    • 0031135465 scopus 로고    scopus 로고
    • Medicinal marijuana and its use by the immunocompromised
    • MCPARTLAND JM, PRUITT PL: Medicinal marijuana and its use by the immunocompromised. Altern. Ther. Health Med. (1997) 3:39-45.
    • (1997) Altern. Ther. Health Med. , vol.3 , pp. 39-45
    • Mcpartland, J.M.1    Pruitt, P.L.2
  • 14
    • 23844510064 scopus 로고    scopus 로고
    • Smoked marijuana as a cause of lung injury
    • TASHKIN DP: Smoked marijuana as a cause of lung injury. Monald Arch. Chest Dis. (2005) 63:93-100.
    • (2005) Monald Arch. Chest Dis. , vol.63 , pp. 93-100
    • Tashkin, D.P.1
  • 15
    • 85007739660 scopus 로고    scopus 로고
    • Cannabis as medicine: Time for the phoenix to arise?
    • ROBSON P: Cannabis as medicine: time for the phoenix to arise? Br. Med. J. (1998) 316:1034-1035.
    • (1998) Br. Med. J. , vol.316 , pp. 1034-1035
    • Robson, P.1
  • 16
    • 16444368192 scopus 로고    scopus 로고
    • Pharmacological and therapeutic targets for delta-9-tetrahydrocannabinol and cannabidiol
    • PERTWEE RG: Pharmacological and therapeutic targets for delta-9-tetrahydrocannabinol and cannabidiol. Euphytica (2004) 140:73-82.
    • (2004) Euphytica , vol.140 , pp. 73-82
    • Pertwee, R.G.1
  • 17
    • 1642417657 scopus 로고    scopus 로고
    • The pharmacology and therapeutic potential of cannabidiol
    • Di Marzo V (Ed.). Kluwer Academic/Plenum Publishers, New York, US
    • PERTWEE RG: The pharmacology and therapeutic potential of cannabidiol. In: Cannabinoids. Di Marzo V (Ed.). Kluwer Academic/Plenum Publishers, New York, US (2004):32-83.
    • (2004) Cannabinoids , pp. 32-83
    • Pertwee, R.G.1
  • 18
    • 0026586613 scopus 로고
    • Human hepatic microsomal metabolism of delta 1-tetrahydrocannabinol
    • BORNHEIM LM, LASKER JM, RAUCY JL: Human hepatic microsomal metabolism of delta 1-tetrahydrocannabinol. Drug Metab. Dispos. (1992) 20(2):241-246.
    • (1992) Drug Metab. Dispos. , vol.20 , Issue.2 , pp. 241-246
    • Bornheim, L.M.1    Lasker, J.M.2    Raucy, J.L.3
  • 19
    • 84902353778 scopus 로고    scopus 로고
    • Metabolism and pharmacokinetics of cannabinoids
    • Guy GW, Whittle BA, Robson PJ (Eds). Pharmaceutical Press, London, UK
    • HAWKSWORTH GM, MCARDLE KE: Metabolism and pharmacokinetics of cannabinoids. In: The Medicinal Uses of Cannabis and Cannabinoids. Guy GW, Whittle BA, Robson PJ (Eds). Pharmaceutical Press, London, UK (2004):205-228.
    • (2004) The Medicinal Uses of Cannabis and Cannabinoids , pp. 205-228
    • Hawksworth, G.M.1    Mcardle, K.E.2
  • 20
    • 33645754286 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism of the plant cannabinoids, delta-9-tetrahydrocannabinol, cannabidiol and cannabinol
    • Pertwee RG (Ed.). Springer-Verlag, Heidelberg, Germany
    • HUESTIS MA: Pharmacokinetics and metabolism of the plant cannabinoids, delta-9-tetrahydrocannabinol, cannabidiol and cannabinol. In: Cannabinoids. Pertwee RG (Ed.). Springer-Verlag, Heidelberg, Germany (2005) 168:657-690.
    • (2005) Cannabinoids , vol.168 , pp. 657-690
    • Huestis, M.A.1
  • 21
    • 0022270590 scopus 로고
    • Excretion patterns of cannabinoid metabolites after last use in a group of chronic users
    • ELLIS GM, MANN MA, JUDSON BA et al.: Excretion patterns of cannabinoid metabolites after last use in a group of chronic users. Clin. Pharmacol. Ther. (1985) 38:572-578.
    • (1985) Clin. Pharmacol. Ther. , vol.38 , pp. 572-578
    • Ellis, G.M.1    Mann, M.A.2    Judson, B.A.3
  • 22
    • 0025257037 scopus 로고
    • Metabolites of cannabidiol identified in human urine
    • HARVEY DJ, MECHOULAM R: Metabolites of cannabidiol identified in human urine. Xenobiotica (1990) 20:303-320.
    • (1990) Xenobiotica , vol.20 , pp. 303-320
    • Harvey, D.J.1    Mechoulam, R.2
  • 23
    • 4344582253 scopus 로고    scopus 로고
    • Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients
    • WADE DT, MAKELA P, ROBSON P et al.: Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients. Mult. Scler. (2004) 10:434-441.
    • (2004) Mult. Scler. , vol.10 , pp. 434-441
    • Wade, D.T.1    Makela, P.2    Robson, P.3
  • 24
    • 0242654882 scopus 로고    scopus 로고
    • Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): Multicentre, randomized, plcacebo controlled trial
    • ZAJICEK J, FOX P, SANDERS H et al.: Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicentre, randomized, plcacebo controlled trial. Lancet (2003) 362:1517-1526.
    • (2003) Lancet , vol.362 , pp. 1517-1526
    • Zajicek, J.1    Fox, P.2    Sanders, H.3
  • 25
    • 0032836781 scopus 로고    scopus 로고
    • A review of the properties and limitations of the Ashworth & modified Ashworth Scales as measures of spasticity
    • PANDYAN AD, JOHNSON GR, PRICE CIM et al.: A review of the properties and limitations of the Ashworth & modified Ashworth Scales as measures of spasticity. Clin. Rehabil. (1999) 13:373-383.
    • (1999) Clin. Rehabil. , vol.13 , pp. 373-383
    • Pandyan, A.D.1    Johnson, G.R.2    Price, C.I.M.3
  • 26
    • 0037406468 scopus 로고    scopus 로고
    • A biomechanical investigation into the validity of the modified Ashworth Scale as a measure of elbow spasticity
    • PANDYAN AD, PRICE CIM, BARNES MP, JOHNSON GR: A biomechanical investigation into the validity of the modified Ashworth Scale as a measure of elbow spasticity. Clin. Rehabil. (2003) 17:290-294.
    • (2003) Clin. Rehabil. , vol.17 , pp. 290-294
    • Pandyan, A.D.1    Price, C.I.M.2    Barnes, M.P.3    Johnson, G.R.4
  • 27
    • 25444530723 scopus 로고    scopus 로고
    • Randomized controlled trial of cannabis-based medicine in central pain in multiple sclerosis
    • ROG DJ, NURMIKKO TJ, FRIEDE T, YOUNG CA: Randomized controlled trial of cannabis-based medicine in central pain in multiple sclerosis. Neurology (2005) 65:812-819.
    • (2005) Neurology , vol.65 , pp. 812-819
    • Rog, D.J.1    Nurmikko, T.J.2    Friede, T.3    Young, C.A.4
  • 28
    • 2442640362 scopus 로고    scopus 로고
    • Effect of Delta-9- tetrahydrocannabinol and cannabidiol on nocturnal sleep and early-morning behavior in young adults
    • NICHOLSON AN, TURNER C, STONE BM, ROBSON PJ: Effect of Delta-9- tetrahydrocannabinol and cannabidiol on nocturnal sleep and early-morning behavior in young adults. J. Clin. Psychopharmacol. (2004) 24:305-313.
    • (2004) J. Clin. Psychopharmacol. , vol.24 , pp. 305-313
    • Nicholson, A.N.1    Turner, C.2    Stone, B.M.3    Robson, P.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.