A novel asymmetric synthesis of tritium and carbon-14 labeled (R)-ibuprofen

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 49, Issue 3, 2006, Pages 237-244

  Zhang, Yinsheng ^a   Hong, Yang ^b   Huang, Che C ^c   Belmont, Daniel ^a  

^a PFIZER INC   (United States)

^b Pharmaceutical Research Institute   (United States)

^c NONE   (United States)

Author keywords

Asymmetric synthesis; Carbon 14; Chiral auxiliary; R ibuprofen; Radioactive labeling; Tritium

Indexed keywords

CARBON;

2-OXAZOLIDINONE; ASYMMETRIC SYNTHESIS; CARBON 14; CHIRAL AUXILIARIES; R-IBUPROFEN; RADIOACTIVE LABELLING;

TRITIUM;

4 METHYL 5 PHENYL 2 OXAZOLIDINONE; CARBON 14; IBUPROFEN; NONSTEROID ANTIINFLAMMATORY AGENT; OXAZOLIDINONE DERIVATIVE; TRITIUM; UNCLASSIFIED DRUG;

ARTICLE; ASYMMETRIC SYNTHESIS; CARBON NUCLEAR MAGNETIC RESONANCE; CHIRALITY; DRUG ACTIVITY; DRUG EFFECT; ENANTIOMER; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE LABELING; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 33645785106     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1040     Document Type: Article

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