Upregulation of the α1-adrenoceptor-induced phosphoinositide and inotropic response in hypothyroid rat heart

Molecular and Cellular Biochemistry

Volumn 283, Issue 1-2, 2006, Pages 93-100

  Jalali, Shahrzad ^a   Durston, Melanie ^a   Panagia, Vincenzo ^a   Mesaeli, Nasrin ^a  

^a ST BONIFACE GENERAL HOSPITAL RESEARCH CENTRE   (Canada)

Author keywords

1 adrenoceptor; Heart; Hyperthyroidism; Hypothyroidism; Phosphoinositides; Phospholipase C; Positive inotropy; Sarcolemma

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ATENOLOL; BETA ADRENERGIC RECEPTOR; CATECHOLAMINE; DRINKING WATER; INOSITOL 1,4,5 TRISPHOSPHATE; ISOPRENALINE; PHENYLEPHRINE; PHOSPHATIDYLINOSITIDE; PHOSPHOLIPASE C; PROPYLTHIOURACIL; ANTITHYROID AGENT; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HEART; HEART MUSCLE CONTRACTILITY; HYPOTHYROIDISM; INOTROPISM; MALE; NONHUMAN; RAT; RECEPTOR DENSITY; RECEPTOR INTRINSIC ACTIVITY; SARCOLEMMA; SIGNAL TRANSDUCTION; ANIMAL; CELL MEMBRANE; DRUG EFFECT; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT; STIMULATION; UPREGULATION;

ANIMALIA;

ANIMALS; ANTITHYROID AGENTS; CELL MEMBRANE; HEART; HYPOTHYROIDISM; INOSITOL 1,4,5-TRISPHOSPHATE; MALE; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHOLIPASE C; PROPYLTHIOURACIL; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-1; SARCOLEMMA; SIGNAL TRANSDUCTION; STIMULATION, CHEMICAL; UP-REGULATION;

EID: 33645768790     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-006-2348-9     Document Type: Article

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