Synthesis of symmetrical and unsymmetrical functionalized arylphosphines from chlorophosphines and organozinc reagents

Synlett

Volumn , Issue 6, 2006, Pages 954-956

  Le Gall, Erwan ^a   Ben Aïssi, Karima ^a   Lachaise, Isabelle ^a   Troupel, Michel ^a  

^a CNRS   (France)

Author keywords

Arylation; Chlorophosphines; Functionalized arylphosphines; Organometallic reagents; Phosphorus

Indexed keywords

PHOSPHINE DERIVATIVE; ZINC DERIVATIVE;

ARTICLE; ARYLATION; CHEMICAL REACTION; CHEMICAL STRUCTURE; SYNTHESIS;

EID: 33645760522     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-939056     Document Type: Article

References (18)

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14. 2O mixture as an eluent afforded the analytically pure phosphine derivative.
15. 3).
16. 4 has been removed from the procedure.
17. In order to add exactly the required amount of the organozinc compound, a titration was realized as follows: aliquots of the solution were exposed to iodine and analyzed using GC. The amount of aryl iodide so obtained was compared to the amount of the starting aryl bromide using dodecane as internal standard.
18. 31P NMR: δ = 29.08 ppm. MS: m/z (rel. intensity) = 322 (40) [M], 321 (100) [M - 1], 213 (21) [M - 109].